Parametric investigation of fixed-tray, semi-continuous distillation column for ethanol separation from water

This work was aimed to evaluate the parameters affecting the separation of model fermentation broth (7 mole% ethanol) using 10-tray, semi-continuous distillation column. Ethanol compositions in distillate and bottoms were determined at different reflux ratios and feed locations. Results show that the distillation of lower ethanol concentration is better carried out at higher reflux ratio with feed charged at the middle or bottom tray for good overall tray efficiency. The distillation unit is able to purify the feed to 78 mole% ethanol in distillate. Through trial-and-error stepping off, about 81 mole% was predicted as optimum ethanol purity at reflux ratio of 2.33, while a lower reflux ratio of 1.44 was estimated for 78 mole%. Fixed-tray, semi-continuous distillation is a suitable option to concentrate fermentation broth with sufficient ethanol purity

Dynamic Mechanical Analysis of Bio-Based and Synthetic Petroleum Based Polymer Foams with Powder Type Organic Filler at Prolonged Ultra-Violet Exposure

Wood powder filler that have been added in the bio-based and epoxy polymer foams can be proved that it have ability to strengthen the structure of polymer foams. In this study, ‘Meranti’ type wood filler has been used as the filler. This study was developed to observe the pore size of each sample when expose to different hours of UV irradiation exposure using Optical Microscopy (OM). This study was also to compare the mechanical properties of every sample with different ratio filler of 0 wt%, 5 wt%, 10 wt%, 15wt% and 20 wt% at different hours of UV irradiation exposure which is 0 hour until 6,000 hours with increment of 2,000 hours. The testing was run by DMA Q800 TA machine. The samples that have 40 x 10 x 5 mm size were clamped in the machine to get the result of their mechanical properties. From the DMA testing, the results will show the value of tan delta, loss modulus and storage modulus. The value of tan delta shows that higher ratio filler will give the high value of tan delta. The epoxy polymer foams with powder filler have the highest value of tan delta compare to bio-based polymer foams. It proves that the higher filler ratio, the lower value of tan delta can be recorded.  The result of storage and loss modulus was found to increase as the more filler ratio filler in the polymer foams. The higher the loss modulus and storage modulus, the lower the temperature. Bio-based polymer foams with high powder filler ratio can dissipate more energy as energy are lost as heat during UV irradiation exposure

Strain Sensor Based on Embedded Fiber Bragg Grating in Thermoplastic Polyurethane Using the 3D Printing Technology for Improved Sensitivity

A new and easy-to-fabricate strain sensor has been developed, based on fiber Bragg grating (FBG) technology embedded into a thermoplastic polyurethane filament using a 3-dimensional (3D) printer. Taking advantage of the flexibility and elastic properties of the thermoplastic polyurethane material, the embedding of the FBG provides durable protection with enhanced flexibility and sensitivity, as compared to the use of a bare FBG. Results of an evaluation of its performance have shown that the FBG sensors embedded in this way can be applied effectively in the measurement of strain, with an average wavelength responsivity of 0.013 5 nm/cm of displacement for tensile strain and −0.014 2 nm/cm for compressive strain, both showing a linearity value of up to 99%. Furthermore, such an embedded FBG-based strain sensor has a sensitivity of ∼1.74 times greater than that of a bare FBG used for strain measurement and is well protected and suitable for in-the-field use. It is also observed that the thermoplastic polyurethane based (TPU-based) FBG strain sensor carries a sensitivity value of ∼2.05 times higher than that of the polylactic acid based (PLA-based) FBG strain sensor proving that TPU material can be made as the material of choice as a “sensing” pad for the FBG

Biaxial 3D-Printed Inclinometer Based on Fiber Bragg Grating Technology

A Fiber Bragg Grating (FBG)-based inclinometer has been developed for field use, designed to incorporate biaxial 3-dimensional (3D) printed tilt sensors (in which four FBGs were used). The inclinometer was characterized by examining its response to a wide range of tilts, over the range from 0° to 90°, towards the inclination axes. An excellent linear correlation between the wavelength shifts and the inclination angle (up to the 90° used) was obtained, showing an average sensitivity of 0.01 nm per degree of inclination angle, for each of the FBGs used. In addition to the four FBGs that form the basis of the inclination measurement, a further FBG was included in the design to allow compensation for any temperature changes experienced during the measurements. The device was calibrated over the range from -25°C to 80°C (corresponding to the extremes of cold and hot weather conditions likely to be experienced in-the-field), and a sensitivity to temperature change of 0.011nm/°C was achieved, allowing an effective temperature correction to be applied. The data obtained from a full characterization of the performance of the sensor system, carried out in a stable, controlled environment, indicate that this inclinometer yields good sensitivity, making it highly applicable for use in monitoring rapid ground movements and deformations with its compact design allowing its wide use

Surface-Mounted Tilt Sensor Using Fiber Bragg Grating Technology for Engineered Slope Monitoring With Temperature Compensation

A surface-mounted tilt sensor was designed and fabricated to measure the inclination angle of engineered structures or slopes in two directions. The device utilizes two strain-sensitive fiber Bragg gratings (FBGs) for tilt angle measurement bidirectionally and one strain-free FBG to provide temperature compensation. In this work, a tilt sensor prototype was fabricated using a 3-D printer, with a robust enclosure and a miniature actuator with dimensions of 115×65×30 mm and 45×20× 3 mm, respectively. The device was first calibrated in the laboratory for tilt and temperature parameters. For tilt calibration, the device yields a sensitivity value of 0.0135 and 0.0123 nm/° for + x- and– x -directions. On the other hand, the device delivers a sensitivity value of 0.0105 nm/°C as the response to temperature changes. The tilt sensor was also tested for suitability in a real-field deployment where it was installed on a retaining wall and was left for four weeks. The field test data indicate no vertical displacement of the wall since the device exhibits zero inclination changes during the test period. This compact, robust, and easy-to-install tilt sensor has excellent potential for various geotechnical applications, mainly in landslide detections, ground movement, and engineered slope monitoring

Optical fiber Bragg grating-based pressure sensor for soil monitoring applications

An optical-based pressure sensor for a 150 × 150 mm surface was designed and fabricated. The sensor utilizes a fiber Bragg grating (FBG) attached to a 30 × 30 × 30 mm actuator as the pressure sensing mechanism. The middle section of the actuator, which is circular, can bend into an elliptical form and, in the process, pull the FBGP via both ends when force or pressure is applied, thus converting the pressure applied to its surface into a wavelength shift. In laboratory testing, a sensitivity of 0.152 nm∕kPa was obtained. Subsequently, the pressure sensor was tested in the field by burying it 20 cm underground to measure soil pressure, while another FBG was spliced in series to the FBGP to compensate for temperature variations. Testing shows that the proposed design can realize a compact optical-based pressure sensor with enhanced soil monitoring applications such as dynamic soil pressure caused by soil movement

Arthropods-mediated green synthesis of zinc oxide nanoparticles using cellar spider extract: a biocompatible remediation for environmental approach

This study presents an eco-friendly approach to synthesizing zinc oxide nanoparticles (ZnO NPs) using extracts from cellar spiders, addressing environmental and health concerns associated with conventional methods. The spider extract efficiently reduced zinc acetate dihydrate, and the synthesized ZnO NPs underwent comprehensive quantitative characterization, including size, shape, morphology, surface chemistry, thermal stability, and optical properties using Fourier-transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), zeta potential measurements, thermogravimetric analysis (TGA), and UV-vis spectroscopy. The nanoparticles exhibited intended characteristics, and their adsorption capability for methylene blue (MB) was quantitatively assessed using the Freundlich isotherm model and pseudo-second-order kinetic model, providing numerical insights into MB removal efficiency. The study demonstrates the potential of these green-synthesized ZnO NPs for applications in environmental remediation, wastewater treatment, and antibacterial therapies, contributing to both sustainable nanomaterial development and quantitative understanding of their functional properties

Impact of primary kidney disease on the effects of empagliflozin in patients with chronic kidney disease: secondary analyses of the EMPA-KIDNEY trial

Background: The EMPA KIDNEY trial showed that empagliflozin reduced the risk of the primary composite outcome of kidney disease progression or cardiovascular death in patients with chronic kidney disease mainly through slowing progression. We aimed to assess how effects of empagliflozin might differ by primary kidney disease across its broad population. Methods: EMPA-KIDNEY, a randomised, controlled, phase 3 trial, was conducted at 241 centres in eight countries (Canada, China, Germany, Italy, Japan, Malaysia, the UK, and the USA). Patients were eligible if their estimated glomerular filtration rate (eGFR) was 20 to less than 45 mL/min per 1·73 m2, or 45 to less than 90 mL/min per 1·73 m2 with a urinary albumin-to-creatinine ratio (uACR) of 200 mg/g or higher at screening. They were randomly assigned (1:1) to 10 mg oral empagliflozin once daily or matching placebo. Effects on kidney disease progression (defined as a sustained ≥40% eGFR decline from randomisation, end-stage kidney disease, a sustained eGFR below 10 mL/min per 1·73 m2, or death from kidney failure) were assessed using prespecified Cox models, and eGFR slope analyses used shared parameter models. Subgroup comparisons were performed by including relevant interaction terms in models. EMPA-KIDNEY is registered with ClinicalTrials.gov, NCT03594110. Findings: Between May 15, 2019, and April 16, 2021, 6609 participants were randomly assigned and followed up for a median of 2·0 years (IQR 1·5–2·4). Prespecified subgroupings by primary kidney disease included 2057 (31·1%) participants with diabetic kidney disease, 1669 (25·3%) with glomerular disease, 1445 (21·9%) with hypertensive or renovascular disease, and 1438 (21·8%) with other or unknown causes. Kidney disease progression occurred in 384 (11·6%) of 3304 patients in the empagliflozin group and 504 (15·2%) of 3305 patients in the placebo group (hazard ratio 0·71 [95% CI 0·62–0·81]), with no evidence that the relative effect size varied significantly by primary kidney disease (pheterogeneity=0·62). The between-group difference in chronic eGFR slopes (ie, from 2 months to final follow-up) was 1·37 mL/min per 1·73 m2 per year (95% CI 1·16–1·59), representing a 50% (42–58) reduction in the rate of chronic eGFR decline. This relative effect of empagliflozin on chronic eGFR slope was similar in analyses by different primary kidney diseases, including in explorations by type of glomerular disease and diabetes (p values for heterogeneity all >0·1). Interpretation: In a broad range of patients with chronic kidney disease at risk of progression, including a wide range of non-diabetic causes of chronic kidney disease, empagliflozin reduced risk of kidney disease progression. Relative effect sizes were broadly similar irrespective of the cause of primary kidney disease, suggesting that SGLT2 inhibitors should be part of a standard of care to minimise risk of kidney failure in chronic kidney disease. Funding: Boehringer Ingelheim, Eli Lilly, and UK Medical Research Council