Natural Solid Shampoo: Pashoo

Pashoo es una empresa que se creó gracias a la idea de cinco estudiantes que se encuentran cursando el décimo ciclo en la Universidad Peruana de Ciencias Aplicadas (UPC), la cual está orientada a la industria de cuidado de belleza y salud mediante la fabricación y comercialización de shampoo en barra 100% naturales a base de ingredientes seleccionados de acuerdo con sus valores nutricionales que estos le brindan al cabello. Contamos con shampoos de distintos olores y para todo tipo de cabellos como por ejemplo shampoo a base de aceite de jojoba, coco, almendras, argán y palta combinados con esencias naturales que le brindan al cliente una sensación de relajación. Por otro lado, hemos segmentado a nuestros clientes de manera que nuestro producto pueda solucionar sus problemas. Para este proyecto, nos estamos fijando en las mujeres que tienen problemas de caída de cabello e irritación en el cuero cabelludo y que estén buscando productos orgánicos y naturales que tengan conciencia sobre el cuidado del medio ambiente. Vamos a distribuir nuestros productos mediante ferias y por delivery utilizando como canales de comunicación las redes sociales y nuestra página web en donde los clientes podrán encontrar información necesaria sobre nosotros y nuestros productos. De la misma forma, mostrar las validaciones del modelo de negocio, el desarrollo del negocio, el plan financiero y de marketing, así como las operaciones que se realizaron a lo largo de este proyecto dejando por último nuestras conclusiones y recomendaciones por la realización del proyecto de negocio.Pashoo is a company that was created thanks to the idea of five students who are studying the tenth cycle at the Universidad Peruana de Ciencias Aplicadas (UPC), which is oriented to the beauty and health care industry through manufacturing and marketing 100% natural bar shampoo based on selected ingredients according to their nutritional values that they provide to the hair. We have shampoos of different scents and for all types of hair such as jojoba oil, coconut, almond, argan and avocado shampoo combined with natural essences that give the client a feeling of relaxation. On the other hand, we have segmented our customers so that our product can solve their problems. For this project, we are looking at women who have problems with hair loss and irritation on the scalp and who are looking for organic and natural products that are aware of the care of the environment. We will distribute our products through fairs and by delivery using social media and our webpage as communication channels where customers can find necessary information about us and our products. In the same way, show the validations of the business model, the development of the business, the financial and marketing plan, as well as the operations that were carried out throughout this project, finally leaving our conclusions and recommendations for the completion of the project of business.Trabajo de investigació

Correction to: Comparative effectiveness and safety of non-vitamin K antagonists for atrial fibrillation in clinical practice: GLORIA-AF Registry

International audienceIn this article, the name of the GLORIA-AF investigator Anastasios Kollias was given incorrectly as Athanasios Kollias in the Acknowledgements. The original article has been corrected

Patterns of oral anticoagulant use and outcomes in Asian patients with atrial fibrillation: a post-hoc analysis from the GLORIA-AF Registry

Background: Previous studies suggested potential ethnic differences in the management and outcomes of atrial fibrillation (AF). We aim to analyse oral anticoagulant (OAC) prescription, discontinuation, and risk of adverse outcomes in Asian patients with AF, using data from a global prospective cohort study. Methods: From the GLORIA-AF Registry Phase II-III (November 2011-December 2014 for Phase II, and January 2014-December 2016 for Phase III), we analysed patients according to their self-reported ethnicity (Asian vs. non-Asian), as well as according to Asian subgroups (Chinese, Japanese, Korean and other Asian). Logistic regression was used to analyse OAC prescription, while the risk of OAC discontinuation and adverse outcomes were analysed through Cox-regression model. Our primary outcome was the composite of all-cause death and major adverse cardiovascular events (MACE). The original studies were registered with ClinicalTrials.gov, NCT01468701, NCT01671007, and NCT01937377. Findings: 34,421 patients were included (70.0 ± 10.5 years, 45.1% females, 6900 (20.0%) Asian: 3829 (55.5%) Chinese, 814 (11.8%) Japanese, 1964 (28.5%) Korean and 293 (4.2%) other Asian). Most of the Asian patients were recruited in Asia (n = 6701, 97.1%), while non-Asian patients were mainly recruited in Europe (n = 15,449, 56.1%) and North America (n = 8378, 30.4%). Compared to non-Asian individuals, prescription of OAC and non-vitamin K antagonist oral anticoagulant (NOAC) was lower in Asian patients (Odds Ratio [OR] and 95% Confidence Intervals (CI): 0.23 [0.22-0.25] and 0.66 [0.61-0.71], respectively), but higher in the Japanese subgroup. Asian ethnicity was also associated with higher risk of OAC discontinuation (Hazard Ratio [HR] and [95% CI]: 1.79 [1.67-1.92]), and lower risk of the primary composite outcome (HR [95% CI]: 0.86 [0.76-0.96]). Among the exploratory secondary outcomes, Asian ethnicity was associated with higher risks of thromboembolism and intracranial haemorrhage, and lower risk of major bleeding. Interpretation: Our results showed that Asian patients with AF showed suboptimal thromboembolic risk management and a specific risk profile of adverse outcomes; these differences may also reflect differences in country-specific factors. Ensuring integrated and appropriate treatment of these patients is crucial to improve their prognosis. Funding: The GLORIA-AF Registry was funded by Boehringer Ingelheim GmbH