Leishmaniasis Cutánea: panorama epidemiológico en la región Nordeste brasileña, Región Metropolitana del Gran São Luís (2010-2020)

Introdução: Leishmaniose Tegumentar é uma doença parasitária que apresenta alta incidência em regiões de clima tropical e subtropical. Ao longo dos anos apresenta alta expansão em todas as regiões brasileiras, com destaque para o Norte e Nordeste que evidencia populações vulneráveis como as mais atingidas. Investigar a epidemiologia destas doenças são fundamentais para a formulação e implementação de políticas públicas de saúde com o objetivo de prevenção e combate ao inseto vetor. Objetivo: Descrever os dados epidemiológicos e sua relação com variáveis sociodemográficas em relação à incidência de Leishmaniose Tegumentar na Região Metropolitana da Grande São Luís entre os anos de 2010 a 2020. Metodologia: Estudo epidemiológico de abordagem quantitativa e retrospectiva que utilizou dados secundários em relação aos casos confirmados da doença entre os anos de 2010 a 2020 para a região de estudo e variáveis qualitativas. Resultados: Os dados mostraram maior incidência da doença em indivíduos do sexo masculino, de cor parda e com ensino fundamental incompleto. Conclusão: Ações desenvolvidas por parte das esferas públicas com o objetivo de divulgação de campanhas preventivas associadas a investimento financeiro e técnico às universidades e centros de pesquisa contribuem para o desenvolvimento de pesquisas e elaboração de medidas que atuem nas interfaces de prevenção, tratamento, controle e erradicação das principais doenças tropicais negligenciadas.info:eu-repo/semantics/publishedVersio

EPIDEMIOLOGICAL PROFILE OF ARBOVIROSIS IN THE STATE OF MARANHÃO: DENGUE FROM 2010 TO 2020

Dengue is an arbovirus considered a growing problem in relation to public health worldwide. With this, the objective of this work is to describe, in a retrospective and analytical way, the epidemiological profile and the spatial distribution of dengue cases in the state of Maranhão between the years 2010 to 2020. This quantitative and retrospective study used secondary data provided by the State Department of Health (SES-MA) of confirmed and notified cases of the disease in a time frame between 2010 and 2020. In addition, geoprocessing techniques were also used to spatialize the data. The results indicate that there were oscillations in relation to confirmed and reported cases throughout this period in the state, especially in the north and southwest regions. Thus, Maranhão reveals a critical state in relation to the occurrence of the disease, which is possibly associated with environmental factors, infrastructure and lack of public policies related to basic sanitation.info:eu-repo/semantics/publishedVersio

Systematic Review of Treatment Failure and Clinical Relapses in Leishmaniasis from a Multifactorial Perspective: Clinical Aspects, Factors Associated with the Parasite and Host

Leishmaniasis is a disease caused by protozoa of the genus Leishmania. Treatment options are limited, and there are frequent cases of treatment failure and clinical relapse. To understand these phenomena better, a systematic review was conducted, considering studies published between 1990 and 2021 in Portuguese, English, and Spanish. The review included 64 articles divided into three categories. Case reports (26 articles) focused on treatment failure and clinical relapse in cutaneous leishmaniasis patients (47.6%), primarily affecting males (74%) and children (67%), regardless of the clinical manifestation. Experimental studies on the parasite (19 articles), particularly with L. major (25%), indicated that alterations in DNA and genic expression (44.82%) played a significant role in treatment failure and clinical relapse. Population data on the human host (19 articles) identified immunological characteristics as the most associated factor (36%) with treatment failure and clinical relapse. Each clinical manifestation of the disease presented specificities in these phenomena, suggesting a multifactorial nature. Additionally, the parasites were found to adapt to the drugs used in treatment. In summary, the systematic review revealed that treatment failure and clinical relapse in leishmaniasis are complex processes influenced by various factors, including host immunology and parasite adaptation

Resumos concluídos - Saúde Coletiva

Resumos concluídos - Saúde Coletiv

NEOTROPICAL ALIEN MAMMALS: a data set of occurrence and abundance of alien mammals in the Neotropics

Biological invasion is one of the main threats to native biodiversity. For a species to become invasive, it must be voluntarily or involuntarily introduced by humans into a nonnative habitat. Mammals were among first taxa to be introduced worldwide for game, meat, and labor, yet the number of species introduced in the Neotropics remains unknown. In this data set, we make available occurrence and abundance data on mammal species that (1) transposed a geographical barrier and (2) were voluntarily or involuntarily introduced by humans into the Neotropics. Our data set is composed of 73,738 historical and current georeferenced records on alien mammal species of which around 96% correspond to occurrence data on 77 species belonging to eight orders and 26 families. Data cover 26 continental countries in the Neotropics, ranging from Mexico and its frontier regions (southern Florida and coastal-central Florida in the southeast United States) to Argentina, Paraguay, Chile, and Uruguay, and the 13 countries of Caribbean islands. Our data set also includes neotropical species (e.g., Callithrix sp., Myocastor coypus, Nasua nasua) considered alien in particular areas of Neotropics. The most numerous species in terms of records are from Bos sp. (n = 37,782), Sus scrofa (n = 6,730), and Canis familiaris (n = 10,084); 17 species were represented by only one record (e.g., Syncerus caffer, Cervus timorensis, Cervus unicolor, Canis latrans). Primates have the highest number of species in the data set (n = 20 species), partly because of uncertainties regarding taxonomic identification of the genera Callithrix, which includes the species Callithrix aurita, Callithrix flaviceps, Callithrix geoffroyi, Callithrix jacchus, Callithrix kuhlii, Callithrix penicillata, and their hybrids. This unique data set will be a valuable source of information on invasion risk assessments, biodiversity redistribution and conservation-related research. There are no copyright restrictions. Please cite this data paper when using the data in publications. We also request that researchers and teachers inform us on how they are using the data

Brazilian Flora 2020: Leveraging the power of a collaborative scientific network

International audienceThe shortage of reliable primary taxonomic data limits the description of biological taxa and the understanding of biodiversity patterns and processes, complicating biogeographical, ecological, and evolutionary studies. This deficit creates a significant taxonomic impediment to biodiversity research and conservation planning. The taxonomic impediment and the biodiversity crisis are widely recognized, highlighting the urgent need for reliable taxonomic data. Over the past decade, numerous countries worldwide have devoted considerable effort to Target 1 of the Global Strategy for Plant Conservation (GSPC), which called for the preparation of a working list of all known plant species by 2010 and an online world Flora by 2020. Brazil is a megadiverse country, home to more of the world's known plant species than any other country. Despite that, Flora Brasiliensis, concluded in 1906, was the last comprehensive treatment of the Brazilian flora. The lack of accurate estimates of the number of species of algae, fungi, and plants occurring in Brazil contributes to the prevailing taxonomic impediment and delays progress towards the GSPC targets. Over the past 12 years, a legion of taxonomists motivated to meet Target 1 of the GSPC, worked together to gather and integrate knowledge on the algal, plant, and fungal diversity of Brazil. Overall, a team of about 980 taxonomists joined efforts in a highly collaborative project that used cybertaxonomy to prepare an updated Flora of Brazil, showing the power of scientific collaboration to reach ambitious goals. This paper presents an overview of the Brazilian Flora 2020 and provides taxonomic and spatial updates on the algae, fungi, and plants found in one of the world's most biodiverse countries. We further identify collection gaps and summarize future goals that extend beyond 2020. Our results show that Brazil is home to 46,975 native species of algae, fungi, and plants, of which 19,669 are endemic to the country. The data compiled to date suggests that the Atlantic Rainforest might be the most diverse Brazilian domain for all plant groups except gymnosperms, which are most diverse in the Amazon. However, scientific knowledge of Brazilian diversity is still unequally distributed, with the Atlantic Rainforest and the Cerrado being the most intensively sampled and studied biomes in the country. In times of “scientific reductionism”, with botanical and mycological sciences suffering pervasive depreciation in recent decades, the first online Flora of Brazil 2020 significantly enhanced the quality and quantity of taxonomic data available for algae, fungi, and plants from Brazil. This project also made all the information freely available online, providing a firm foundation for future research and for the management, conservation, and sustainable use of the Brazilian funga and flora