Endocrine disorders and fertility and pregnancy: An update

It is estimated that more and more couples suffer from fertility and pregnancy maintenance disorders. It is associated with impaired androgen secretion, which is influenced by many factors, ranging from genetic to environmental. It is also important to remember that fertility disorders can also result from abnormal anatomy of the reproductive male and female organ (congenital uterine anomalies – septate, unicornuate, bicornuate uterus; acquired defects of the uterus structure – fibroids, polyps, hypertrophy), disturbed hormonal cycle and obstruction of the fallopian tubes resulting from the presence of adhesions due to inflammation, endometriosis, and surgery, abnormal rhythm of menstrual bleeding, the abnormal concentration of hormones. There are many relationships between the endocrine organs, leading to a chain reaction when one of them fails to function properly. Conditions in which the immune system is involved, including infections and autoimmune diseases, also affect fertility. The form of treatment depends on infertility duration and the patient’s age. It includes ovulation stimulation with clomiphene citrate or gonadotropins, metformin use, and weight loss interventions. Since so many different factors affect fertility, it is important to correctly diagnose what is causing the problem and to modify the treatment regimen if necessary. This review describes disturbances in the hormone secretion of individual endocrine organs in the context of fertility and the maintenance of pregnancy

Local geometric structure of selected Banach function spaces

Wydział Matematyki i InformatykiW rozprawie przedstawione są wyniki dotyczące pewnych lokalnych własności geometrycznych w wybranych klasach krat Banacha, tj. symetrycznych przestrzeniach Banacha wraz z ich szczególnymi przypadkami - przestrzeniami Lorentza, a także uogólnionych przestrzeniach Calderona-Łozanowskiego. Wyniki dotyczą m.in. punktów monotoniczności, punktów porządkowej ciągłości i punktów niekwadratowości. Podane są również wnioski dla szczególnych przypadków przestrzeni, a także wywnioskowane są analogiczne własności globalne. Omówiony jest ponadto problem najlepszej lokalnej zdominowanej aproksymacji dla siatek Banacha i przestrzeni symetrycznych.The dissertation presents results concerning some local geometric properties of such classes of Banach lattices as symmetric spaces, together with Lorentz spaces, and generalized Calderon-Lozanovskii spaces. The results are mainly about monotonicity points, order continuous points and nonsquare points. Applications to other special cases of discussed spaces as well as conclusions of analogical global space properties are also given. In addition, the local best dominated approximation problems in Banach lattices and symmetric spaces are discussed

Local geometric structure of selected Banach function spaces

Wydział Matematyki i InformatykiW rozprawie przedstawione są wyniki dotyczące pewnych lokalnych własności geometrycznych w wybranych klasach krat Banacha, tj. symetrycznych przestrzeniach Banacha wraz z ich szczególnymi przypadkami - przestrzeniami Lorentza, a także uogólnionych przestrzeniach Calderona-Łozanowskiego. Wyniki dotyczą m.in. punktów monotoniczności, punktów porządkowej ciągłości i punktów niekwadratowości. Podane są również wnioski dla szczególnych przypadków przestrzeni, a także wywnioskowane są analogiczne własności globalne. Omówiony jest ponadto problem najlepszej lokalnej zdominowanej aproksymacji dla siatek Banacha i przestrzeni symetrycznych.The dissertation presents results concerning some local geometric properties of such classes of Banach lattices as symmetric spaces, together with Lorentz spaces, and generalized Calderon-Lozanovskii spaces. The results are mainly about monotonicity points, order continuous points and nonsquare points. Applications to other special cases of discussed spaces as well as conclusions of analogical global space properties are also given. In addition, the local best dominated approximation problems in Banach lattices and symmetric spaces are discussed

The Effect of Long-Term Frozen Storage on the Quality of Meat (Longissimus thoracis et Lumborum) from Female Roe Deer (Capreolus capreolus L.)

The objective of this study was to determine the quality of meat (Longissimus thoracis et lumborum) from 10 female roe deer (Capreolus capreolus L.), which was vacuum-packaged, frozen-stored (−26°C) for 6, 10, and 12 months, and compared with fresh, nonfrozen meat. Roe deer (aged 3 to 5 years) were hunter-harvested in north-eastern Poland in December and January during the same hunting season. Frozen storage did not affect the proximate chemical composition of meat (except for ash content). An analysis of the physicochemical properties of meat revealed that frozen-stored meat was characterized by a darker color, a higher hue angle, lower ability to bind its own and added water, and lower cooking loss compared with nonfrozen meat. The values noted for meat samples that were stored in the freezer for 12 months (increase in pH, considerable decrease in water-holding capacity, and first symptoms of flavor deterioration) indicate that frozen roe deer meat should be stored for no more than 10 to 12 months to maintain its high quality

The Impact of Surgical Treatment with Adjuvant Chemotherapy for Ovarian Cancer on Disorders in the Urinary System and Quality of Life in Women

Ovarian cancer is the fourth-most-common cause of death among all malignant cancers in women in Poland. This study aimed to compare the functioning of the urinary system and quality of life in women in the 12-month period following the completion of surgery or adjuvant treatment for ovarian cancer, with patients who underwent a hysterectomy for non-oncological reasons (control group). The study group consisted of 50 patients diagnosed with stage I–III ovarian cancer. Among 38 patients with type II ovarian cancer (group A), surgery followed by first-line chemotherapy was performed. Within this group of patients, 20 had stage I ovarian cancer, while 18 had stage II ovarian cancer. The study was performed at least 6 months after the final chemotherapy cycle, with no clinical, marker or radiological recurrence determined. On the other hand, in 12 patients with stage I type I ovarian cancer, oncological treatment consisted of only surgery, without the need for adjuvant chemotherapy, due to the low stage of the lesions (group B). In turn, the control group consisted of 50 women who underwent uterine removal for non-oncological reasons (group C). The assessment of quality of life was conducted using the questionnaires: Satisfaction with Life Scale (SWLS); Incontinence Impact Questionnaire, short form (IIQ-7); Urogenital Distress Inventory (UDI-6); and the Sexual Satisfaction Scale for 3, 6, 9, and 12 months after the conclusion of oncological treatment. During the follow-up, a significant reduction in the quality of everyday life and sexual life was noted among patients with ovarian cancer, more pronounced in group B, compared to the control group (p < 0.05). The risk of urinary incontinence is independent of the treatment regimen chosen for ovarian cancer. It is necessary to consider comprehensive psychological care and sexual therapy in patients with ovarian cancer and their families