66 research outputs found

    Major trends in efficiency upgrading of the economic activity in the Arctic zone of Russian Federation

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    Organization of efficient economic activity in the Arctic zone requires development of human potential, transport infrastructure, exploitation of natural resources under the conditions of greatest possible environmental safety. In order to choose preferable trends of economic development and to provide efficiency of operations in the Arctic zone it is crucial to perform research in the areas of industrial efficiency upgrading and rational use of fuel, energy, mineral, chemical and biological resources of the Ocean and littoral areas of Russian Arctic.The paper analyzes major trends in the research on increasing economic efficiency of operations aimed at territory development in the Arctic zone. The authors justify the need to examine economic problems of rational resource use in the Arctic zone of Russia based on the proposed system of resource-estimation indicators and their application in establishing a mechanism of rational resource use with a due regard to protection of the marine environment. The paper also focuses on methodological problems of the target programme approach to complex development of the Arctic zone, creation of target programmes, industrial development and rational use of natural resources. The authors give rationale for the key task in this area – development of methodological principles of forming federal and regional target programmes, aimed at exploration, exploitation and rational use of natural resources in the Arctic zone of Russian Federation. An analysis is provided that focuses on the problems of creating a scientifically justified hierarchical system of programmes and regional regulations, creation of a scientific information data bank and other methodological issues

    Infiornativity lacrimal fluid interleukins in diagnostics and development of angle-closure glaucoma in elderly subjects

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    An increased percentage of the elderly subjects in pattern of contemporary society, along with other causes and risk factors, is accompanied by rise in the incidence of glaucoma. By 2020, according to international studies it is expected that prevalence of glaucoma patients in the world would increase up to 80 million subjects. Among the elderly, glaucoma is a common pathology, which development is associated with local disturbances in interleukin profile. However, the features of the latter in patients with primary closed-angle glaucoma in the elderly were poorly examined. Studies of local interleukin status were conducted mainly in patients with suspected or initial manifestations of primary open-angle glaucoma. The features of lacrimal fluid interleukin shift in a target group of elderly patients suffering from stage II primary closed-angle glaucoma virtually gained no attention. In addition, a limited range of local interleukins in patients with such pathology in previous studies was examined. In addition, informativity of lacrimal fluid interleukins in elderly glaucoma patients was not assessed too based on objective methods. The aim of the current study was to outline features and informativity of local interleukin profile indicators in 58 elderly patients with primary closed-angle glaucoma stage II, aged 60β€”74 years (main group) and 27 age-matched elderly subjects lacking such pathology. The level of interleukins in the lacrimal fluid was determined with the enzyme immunoassay β€œMultiscan” analyzer (Finland) by using sandwich ELISA (R&D Diagnostic Inc., USA). Informativity of measuring various interleukins was calculated according to the generally accepted formula. It was found that local interleukin profile in elderly patients with primary closed-angle glaucoma was mainly featured with increased amount of IL-2, IL-17, IL-8, but decreased IL-10. Hence, such local interleukins displayed peak informativity. The data obtained should be used in the diagnostics and treatment of such pathology, as well as of applied importance to unveil novel mechanisms behind development, diagnostics and corroboration for selective immuno-tropic therapy of primary closed-angle glaucoma

    Applying Financial Information to Manage Corporate Risks from the COVID‑19 Pandemic

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    The COVID-19 pandemic has had a significant impact on the economy at all levels, from global markets to micro-enterprises. At the same time, the pandemic and its consequences have left a wide digital footprint. Its study seems to be extremely relevant, since approaches to the analysis of the digital footprint of a pandemic and the use of its results for risk management can be successfully applied in the event of similar threats. The relevance of the problem is also recognized by economists who note the significant impact of the pandemic on the economy and economic theory in general. The aim of the study is to develop approaches to the rapid quantitative assessment of the impact of the pandemic on the university based on the data of accounting financial systems, their testing and generation of proposals for minimizing the risks of financial and economic activities. The scientific hypothesis of the study is that based on the analysis of data transmitted to the social insurance fund on the disability of employees, the effectiveness of risk management of financial and economic activities in a pandemic at the university level can be improved. Growth in efficiency is ensured by adjusting plans to minimize risks, taking into account the heterogeneity of the impact of the pandemic on employees depending on age, gender, and belonging to the category of personnel. For data integration and analysis, the authors used Data Science approaches. Using the data of Ural Federal University as an example, the information content of the analyzed data is shown and what management decisions to minimize risks can be made on their basis. An approach to the quantitative analysis of the impact of the pandemic on employees of a legal entity is proposed. The effectiveness of using distance learning to counter the pandemic, the vulnerability to the pandemic of certain categories of employees, the gender structure of disability are demonstrated. The theoretical significance of the work lies in the development of approaches to the use of financial information to improve risk management. The information obtained can be applied in practice, in particular, to clarify the calculation of reserves, improve technical specifications in the development of information systems.ПандСмия COVID-19 ΠΎΠΊΠ°Π·Π°Π»Π° сущСствСнноС влияниС Π½Π° экономику Π½Π° всСх уровнях, ΠΎΡ‚ Π³Π»ΠΎΠ±Π°Π»ΡŒΠ½Ρ‹Ρ… Ρ€Ρ‹Π½ΠΊΠΎΠ² Π΄ΠΎ микропрСдприятий. ΠŸΡ€ΠΈ этом пандСмия ΠΈ Π΅Π΅ послСдствия оставили ΡˆΠΈΡ€ΠΎΠΊΠΈΠΉ Ρ†ΠΈΡ„Ρ€ΠΎΠ²ΠΎΠΉ слСд. Π•Π³ΠΎ ΠΈΠ·ΡƒΡ‡Π΅Π½ΠΈΠ΅ прСдставляСтся Ρ‡Ρ€Π΅Π·Π²Ρ‹Ρ‡Π°ΠΉΠ½ΠΎ Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹ΠΌ, Ρ‚Π°ΠΊ ΠΊΠ°ΠΊ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Ρ‹ ΠΊ Π°Π½Π°Π»ΠΈΠ·Ρƒ Ρ†ΠΈΡ„Ρ€ΠΎΠ²ΠΎΠ³ΠΎ слСда ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ ΠΈ использованиС Π΅Π³ΠΎ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΎΠ² для управлСния рисками ΠΌΠΎΠ³ΡƒΡ‚ Π±Ρ‹Ρ‚ΡŒ ΡƒΡΠΏΠ΅ΡˆΠ½ΠΎ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½Ρ‹ Π² случаС возникновСния Π°Π½Π°Π»ΠΎΠ³ΠΈΡ‡Π½Ρ‹Ρ… ΡƒΠ³Ρ€ΠΎΠ·. ΠΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ признаСтся ΠΈ ΡƒΡ‡Π΅Π½Ρ‹ΠΌΠΈ-экономистами, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ ΠΎΡ‚ΠΌΠ΅Ρ‡Π°ΡŽΡ‚ сущСствСнноС влияниС ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ Π½Π° экономику ΠΈ ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡ‡Π΅ΡΠΊΡƒΡŽ Ρ‚Π΅ΠΎΡ€ΠΈΡŽ Π² Ρ†Π΅Π»ΠΎΠΌ. ЦСлью исслСдования являСтся Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ° ΠΏΠΎΠ΄Ρ…ΠΎΠ΄ΠΎΠ² ΠΊ ΠΎΠΏΠ΅Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΎΠΉ количСствСнной ΠΎΡ†Π΅Π½ΠΊΠ΅ влияния ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ Π½Π° унивСрситСт Π½Π° основС Π΄Π°Π½Π½Ρ‹Ρ… ΡƒΡ‡Π΅Ρ‚Π½Ρ‹Ρ… финансовых систСм, ΠΈΡ… апробация ΠΈ гСнСрация ΠΏΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½ΠΈΠΉ ΠΏΠΎ ΠΌΠΈΠ½ΠΈΠΌΠΈΠ·Π°Ρ†ΠΈΠΈ рисков финансово-хозяйствСнной Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ. Научная Π³ΠΈΠΏΠΎΡ‚Π΅Π·Π° исслСдования состоит Π² Ρ‚ΠΎΠΌ, Ρ‡Ρ‚ΠΎ Π½Π° основС Π°Π½Π°Π»ΠΈΠ·Π° Π΄Π°Π½Π½Ρ‹Ρ…, ΠΏΠ΅Ρ€Π΅Π΄Π°Π²Π°Π΅ΠΌΡ‹Ρ… Ρ„ΠΎΠ½Π΄Ρƒ ΡΠΎΡ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ страхования, ΠΎ нСтрудоспособности сотрудников ΠΌΠΎΠΆΠ΅Ρ‚ Π±Ρ‹Ρ‚ΡŒ ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½Π° ΡΡ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ управлСния рисками финансово-хозяйствСнной Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ Π² условиях ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ Π½Π° ΡƒΡ€ΠΎΠ²Π½Π΅ унивСрситСта. Рост эффСктивности обСспСчиваСтся ΠΊΠΎΡ€Ρ€Π΅ΠΊΡ†ΠΈΠ΅ΠΉ ΠΏΠ»Π°Π½ΠΎΠ² ΠΏΠΎ ΠΌΠΈΠ½ΠΈΠΌΠΈΠ·Π°Ρ†ΠΈΠΈ рисков с ΡƒΡ‡Π΅Ρ‚ΠΎΠΌ нСоднородности влияния ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ Π½Π° сотрудников Π² зависимости ΠΎΡ‚ возраста, Π³Π΅Π½Π΄Π΅Ρ€Π°, принадлСТности ΠΊ ΠΊΠ°Ρ‚Π΅Π³ΠΎΡ€ΠΈΠΈ пСрсонала. Для ΠΈΠ½Ρ‚Π΅Π³Ρ€Π°Ρ†ΠΈΠΈ ΠΈ Π°Π½Π°Π»ΠΈΠ·Π° Π΄Π°Π½Π½Ρ‹Ρ… Π°Π²Ρ‚ΠΎΡ€Π°ΠΌΠΈ использовались ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Ρ‹ Data Science. На ΠΏΡ€ΠΈΠΌΠ΅Ρ€Π΅ Π΄Π°Π½Π½Ρ‹Ρ… Π£Ρ€Π°Π»ΡŒΡΠΊΠΎΠ³ΠΎ Ρ„Π΅Π΄Π΅Ρ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ унивСрситСта ΠΏΠΎΠΊΠ°Π·Π°Π½Π° ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ Π°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΡƒΠ΅ΠΌΡ‹Ρ… Π΄Π°Π½Π½Ρ‹Ρ… ΠΈ ΠΊΠ°ΠΊΠΈΠ΅ управлСнчСскиС Ρ€Π΅ΡˆΠ΅Π½ΠΈΡ ΠΏΠΎ ΠΌΠΈΠ½ΠΈΠΌΠΈΠ·Π°Ρ†ΠΈΠΈ рисков ΠΌΠΎΠ³ΡƒΡ‚ Π±Ρ‹Ρ‚ΡŒ приняты Π½Π° ΠΈΡ… основС. ΠŸΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄ ΠΊ количСствСнному Π°Π½Π°Π»ΠΈΠ·Ρƒ воздСйствия ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ Π½Π° сотрудников ΡŽΡ€ΠΈΠ΄ΠΈΡ‡Π΅ΡΠΊΠΎΠ³ΠΎ Π»ΠΈΡ†Π°. ΠŸΡ€ΠΎΠ΄Π΅ΠΌΠΎΠ½ΡΡ‚Ρ€ΠΈΡ€ΠΎΠ²Π°Π½Π° ΡΡ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ примСнСния дистанционного обучСния для противодСйствия ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ, ΡƒΡΠ·Π²ΠΈΠΌΠΎΡΡ‚ΡŒ для ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ ΠΎΡ‚Π΄Π΅Π»ΡŒΠ½Ρ‹Ρ… ΠΊΠ°Ρ‚Π΅Π³ΠΎΡ€ΠΈΠΉ сотрудников, гСндСрная структура нСтрудоспособности. ВСорСтичСская Π·Π½Π°Ρ‡ΠΈΠΌΠΎΡΡ‚ΡŒ Ρ€Π°Π±ΠΎΡ‚Ρ‹ состоит Π² Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ΅ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄ΠΎΠ² ΠΊ использованию финансовой ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΈ для ΡΠΎΠ²Π΅Ρ€ΡˆΠ΅Π½ΡΡ‚Π²ΠΎΠ²Π°Π½ΠΈΡ управлСния рисками. ΠŸΠΎΠ»ΡƒΡ‡Π΅Π½Π½Π°Ρ информация ΠΌΠΎΠΆΠ΅Ρ‚ Π±Ρ‹Ρ‚ΡŒ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½Π° Π½Π° ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΠ΅, Π² частности, для уточнСния расчСта Ρ€Π΅Π·Π΅Ρ€Π²ΠΎΠ², ΡΠΎΠ²Π΅Ρ€ΡˆΠ΅Π½ΡΡ‚Π²ΠΎΠ²Π°Π½ΠΈΠ΅ тСхничСских Π·Π°Π΄Π°Π½ΠΈΠΉ ΠΏΡ€ΠΈ Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ΅ ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… систСм.ПандСмия COVID-19 ΠΎΠΊΠ°Π·Π°Π»Π° сущСствСнноС влияниС Π½Π° экономику Π½Π° всСх уровнях, ΠΎΡ‚ Π³Π»ΠΎΠ±Π°Π»ΡŒΠ½Ρ‹Ρ… Ρ€Ρ‹Π½ΠΊΠΎΠ² Π΄ΠΎ микропрСдприятий. ΠŸΡ€ΠΈ этом пандСмия ΠΈ Π΅Π΅ послСдствия оставили ΡˆΠΈΡ€ΠΎΠΊΠΈΠΉ Ρ†ΠΈΡ„Ρ€ΠΎΠ²ΠΎΠΉ слСд. Π•Π³ΠΎ ΠΈΠ·ΡƒΡ‡Π΅Π½ΠΈΠ΅ прСдставляСтся Ρ‡Ρ€Π΅Π·Π²Ρ‹Ρ‡Π°ΠΉΠ½ΠΎ Π°ΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½Ρ‹ΠΌ, Ρ‚Π°ΠΊ ΠΊΠ°ΠΊ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Ρ‹ ΠΊ Π°Π½Π°Π»ΠΈΠ·Ρƒ Ρ†ΠΈΡ„Ρ€ΠΎΠ²ΠΎΠ³ΠΎ слСда ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ ΠΈ использованиС Π΅Π³ΠΎ Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚ΠΎΠ² для управлСния рисками ΠΌΠΎΠ³ΡƒΡ‚ Π±Ρ‹Ρ‚ΡŒ ΡƒΡΠΏΠ΅ΡˆΠ½ΠΎ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½Ρ‹ Π² случаС возникновСния Π°Π½Π°Π»ΠΎΠ³ΠΈΡ‡Π½Ρ‹Ρ… ΡƒΠ³Ρ€ΠΎΠ·. ΠΠΊΡ‚ΡƒΠ°Π»ΡŒΠ½ΠΎΡΡ‚ΡŒ ΠΏΡ€ΠΎΠ±Π»Π΅ΠΌΡ‹ признаСтся ΠΈ ΡƒΡ‡Π΅Π½Ρ‹ΠΌΠΈ-экономистами, ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Π΅ ΠΎΡ‚ΠΌΠ΅Ρ‡Π°ΡŽΡ‚ сущСствСнноС влияниС ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ Π½Π° экономику ΠΈ ΡΠΊΠΎΠ½ΠΎΠΌΠΈΡ‡Π΅ΡΠΊΡƒΡŽ Ρ‚Π΅ΠΎΡ€ΠΈΡŽ Π² Ρ†Π΅Π»ΠΎΠΌ. ЦСлью исслСдования являСтся Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ° ΠΏΠΎΠ΄Ρ…ΠΎΠ΄ΠΎΠ² ΠΊ ΠΎΠΏΠ΅Ρ€Π°Ρ‚ΠΈΠ²Π½ΠΎΠΉ количСствСнной ΠΎΡ†Π΅Π½ΠΊΠ΅ влияния ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ Π½Π° унивСрситСт Π½Π° основС Π΄Π°Π½Π½Ρ‹Ρ… ΡƒΡ‡Π΅Ρ‚Π½Ρ‹Ρ… финансовых систСм, ΠΈΡ… апробация ΠΈ гСнСрация ΠΏΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½ΠΈΠΉ ΠΏΠΎ ΠΌΠΈΠ½ΠΈΠΌΠΈΠ·Π°Ρ†ΠΈΠΈ рисков финансово-хозяйствСнной Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ. Научная Π³ΠΈΠΏΠΎΡ‚Π΅Π·Π° исслСдования состоит Π² Ρ‚ΠΎΠΌ, Ρ‡Ρ‚ΠΎ Π½Π° основС Π°Π½Π°Π»ΠΈΠ·Π° Π΄Π°Π½Π½Ρ‹Ρ…, ΠΏΠ΅Ρ€Π΅Π΄Π°Π²Π°Π΅ΠΌΡ‹Ρ… Ρ„ΠΎΠ½Π΄Ρƒ ΡΠΎΡ†ΠΈΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ страхования, ΠΎ нСтрудоспособности сотрудников ΠΌΠΎΠΆΠ΅Ρ‚ Π±Ρ‹Ρ‚ΡŒ ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½Π° ΡΡ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ управлСния рисками финансово-хозяйствСнной Π΄Π΅ΡΡ‚Π΅Π»ΡŒΠ½ΠΎΡΡ‚ΠΈ Π² условиях ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ Π½Π° ΡƒΡ€ΠΎΠ²Π½Π΅ унивСрситСта. Рост эффСктивности обСспСчиваСтся ΠΊΠΎΡ€Ρ€Π΅ΠΊΡ†ΠΈΠ΅ΠΉ ΠΏΠ»Π°Π½ΠΎΠ² ΠΏΠΎ ΠΌΠΈΠ½ΠΈΠΌΠΈΠ·Π°Ρ†ΠΈΠΈ рисков с ΡƒΡ‡Π΅Ρ‚ΠΎΠΌ нСоднородности влияния ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ Π½Π° сотрудников Π² зависимости ΠΎΡ‚ возраста, Π³Π΅Π½Π΄Π΅Ρ€Π°, принадлСТности ΠΊ ΠΊΠ°Ρ‚Π΅Π³ΠΎΡ€ΠΈΠΈ пСрсонала. Для ΠΈΠ½Ρ‚Π΅Π³Ρ€Π°Ρ†ΠΈΠΈ ΠΈ Π°Π½Π°Π»ΠΈΠ·Π° Π΄Π°Π½Π½Ρ‹Ρ… Π°Π²Ρ‚ΠΎΡ€Π°ΠΌΠΈ использовались ΠΏΠΎΠ΄Ρ…ΠΎΠ΄Ρ‹ Data Science. На ΠΏΡ€ΠΈΠΌΠ΅Ρ€Π΅ Π΄Π°Π½Π½Ρ‹Ρ… Π£Ρ€Π°Π»ΡŒΡΠΊΠΎΠ³ΠΎ Ρ„Π΅Π΄Π΅Ρ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ унивСрситСта ΠΏΠΎΠΊΠ°Π·Π°Π½Π° ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ Π°Π½Π°Π»ΠΈΠ·ΠΈΡ€ΡƒΠ΅ΠΌΡ‹Ρ… Π΄Π°Π½Π½Ρ‹Ρ… ΠΈ ΠΊΠ°ΠΊΠΈΠ΅ управлСнчСскиС Ρ€Π΅ΡˆΠ΅Π½ΠΈΡ ΠΏΠΎ ΠΌΠΈΠ½ΠΈΠΌΠΈΠ·Π°Ρ†ΠΈΠΈ рисков ΠΌΠΎΠ³ΡƒΡ‚ Π±Ρ‹Ρ‚ΡŒ приняты Π½Π° ΠΈΡ… основС. ΠŸΡ€Π΅Π΄Π»ΠΎΠΆΠ΅Π½ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄ ΠΊ количСствСнному Π°Π½Π°Π»ΠΈΠ·Ρƒ воздСйствия ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ Π½Π° сотрудников ΡŽΡ€ΠΈΠ΄ΠΈΡ‡Π΅ΡΠΊΠΎΠ³ΠΎ Π»ΠΈΡ†Π°. ΠŸΡ€ΠΎΠ΄Π΅ΠΌΠΎΠ½ΡΡ‚Ρ€ΠΈΡ€ΠΎΠ²Π°Π½Π° ΡΡ„Ρ„Π΅ΠΊΡ‚ΠΈΠ²Π½ΠΎΡΡ‚ΡŒ примСнСния дистанционного обучСния для противодСйствия ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ, ΡƒΡΠ·Π²ΠΈΠΌΠΎΡΡ‚ΡŒ для ΠΏΠ°Π½Π΄Π΅ΠΌΠΈΠΈ ΠΎΡ‚Π΄Π΅Π»ΡŒΠ½Ρ‹Ρ… ΠΊΠ°Ρ‚Π΅Π³ΠΎΡ€ΠΈΠΉ сотрудников, гСндСрная структура нСтрудоспособности. ВСорСтичСская Π·Π½Π°Ρ‡ΠΈΠΌΠΎΡΡ‚ΡŒ Ρ€Π°Π±ΠΎΡ‚Ρ‹ состоит Π² Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ΅ ΠΏΠΎΠ΄Ρ…ΠΎΠ΄ΠΎΠ² ΠΊ использованию финансовой ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΈ для ΡΠΎΠ²Π΅Ρ€ΡˆΠ΅Π½ΡΡ‚Π²ΠΎΠ²Π°Π½ΠΈΡ управлСния рисками. ΠŸΠΎΠ»ΡƒΡ‡Π΅Π½Π½Π°Ρ информация ΠΌΠΎΠΆΠ΅Ρ‚ Π±Ρ‹Ρ‚ΡŒ ΠΏΡ€ΠΈΠΌΠ΅Π½Π΅Π½Π° Π½Π° ΠΏΡ€Π°ΠΊΡ‚ΠΈΠΊΠ΅, Π² частности, для уточнСния расчСта Ρ€Π΅Π·Π΅Ρ€Π²ΠΎΠ², ΡΠΎΠ²Π΅Ρ€ΡˆΠ΅Π½ΡΡ‚Π²ΠΎΠ²Π°Π½ΠΈΠ΅ тСхничСских Π·Π°Π΄Π°Π½ΠΈΠΉ ΠΏΡ€ΠΈ Ρ€Π°Π·Ρ€Π°Π±ΠΎΡ‚ΠΊΠ΅ ΠΈΠ½Ρ„ΠΎΡ€ΠΌΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹Ρ… систСм

    Single-Stage Extracranial and Intracranial Stenting of the Internal Carotid Artery in a Patient with Open Circle of Willis and Associated Renovascular Hypertension

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    We describe a case of 72-year-old patient with recurrent transient ischemic attacks in the right internal carotid artery (ICA) territory associated with uncontrolled hypertension. Duplex ultrasonography und carotid angiography showed a 60% stenosis with signs of a vulnerable plaque in the cervical segment, as well as a 90% stenosis in the cavernous segment of the right ICA. After further examination the patient was diagnosed with an 80% renal artery stenosis. First, the patient had a single-stage stenting for extracranial and intracranial stenoses of the right ICA, then left renal artery stenting. No intraoperative and postoperative complications were observed. These results show that this surgical treatment is minimally invasive, safe, and effective in symptomatic patients and may be considered for the disease

    АллостатичСская Π½Π°Π³Ρ€ΡƒΠ·ΠΊΠ° Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ с Ρ€Π°ΠΊΠΎΠΌ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹

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    Breast cancer is the most common cancer in women worldwide. However, the allostatic load in breast cancer patients has not been sufficiently studied. Objective: to study the allostatic load in middle-aged and elderly patients with breast cancer. Material and methods. The study included 65 middle-aged and 60 elderly patients with histologically confirmed breast cancer and 45 people aged 60-74 years, who had no breast cancer. The allostatic load was studied in these three groups according to the level: systolic and diastolic blood pressure, total cholesterol, triglycerides, high and low density lipoproteins, glucose, albumins and waist circumference. Results. The allostatic load score was significantly higher in elderly breast cancer patients than in middle-aged breast cancer patients (4.3 Β± 0.3 points versus 2.9 Β± 0.2 points, p<0.01). In addition, the allostatic load score in the middle-aged patients with breast cancer was significantly higher (2.7 Β± 0.2 points) than in people of the same age, who had no breast cancer (1.6 Β± 0.1 points). In elderly patients, the allostatic load score was also significantly higher in patients with breast cancer than in people without breast cancer (4.3 Β± 0.3 points and 2.9 Β± 0.2 points, respectively; p<0.001). Significant differences in the allostatic load parameters, such as the levels of total cholesterol (5.8 Β± 1.3 mmol/l versus 4.0 Β± 0.8 mmol/l), and albumin (45.1 Β± 7.4 % versus 61.4 Β± 7.6 %) were found between breast cancer patients aged 60-74 years and people of an identical age, who had no breast cancer. statistically significant differences in allostatic load biomarkers, such as systolic blood pressure, diastolic blood pressure, blood levels of triglycerides and glucose, and waist circumference were found between elderly patients with breast cancer and age controls (without breast cancer). The content of triglycerides in the blood of patients aged 60-74 years with breast cancer was 1.8 times higher than that in patients of the same age with no breast cancer (p<0.001). The blood glucose level was significantly higher in patients with breast cancer than in the age controls (5.8 Β± 1.2 g/l versus 4.4 Β± 1.1 g/l, p<0.01). Conclusion. The allostatic load and its variables should be used as biomarkers of increased risk of breast cancer.Π Π°ΠΊ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ являСтся Π²Π΅Π΄ΡƒΡ‰Π΅ΠΉ Ρ„ΠΎΡ€ΠΌΠΎΠΉ Π½ΠΎΠ²ΠΎΠΎΠ±Ρ€Π°Π·ΠΎΠ²Π°Π½ΠΈΠΉ срСди ΠΆΠ΅Π½Ρ‰ΠΈΠ½ трудоспособного ΠΈ ΠΏΠΎΠΆΠΈΠ»ΠΎΠ³ΠΎ возраста. Однако Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ с Π΄Π°Π½Π½ΠΎΠΉ ΠΏΠ°Ρ‚ΠΎΠ»ΠΎΠ³ΠΈΠ΅ΠΉ нСдостаточно ΠΈΠ·ΡƒΡ‡Π΅Π½Π° аллостатичСская Π½Π°Π³Ρ€ΡƒΠ·ΠΊΠ°. ЦСль исслСдования – ΠΈΠ·ΡƒΡ‡Π΅Π½ΠΈΠ΅ аллостатичСской Π½Π°Π³Ρ€ΡƒΠ·ΠΊΠΈ Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ срСднСго ΠΈ ΠΏΠΎΠΆΠΈΠ»ΠΎΠ³ΠΎ возраста с Ρ€Π°ΠΊΠΎΠΌ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹. ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π» ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹. ΠŸΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΎ обслСдованиС 65 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ срСднСго ΠΈ 60 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ ΠΏΠΎΠΆΠΈΠ»ΠΎΠ³ΠΎ возраста с диагностированным гистологичСски Ρ€Π°ΠΊΠΎΠΌ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ ΠΈ 45 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ Π² возрастС 60–74 Π»Π΅Ρ‚ с отсутствиСм Ρ€Π°ΠΊΠ° ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹. АллостатичСская Π½Π°Π³Ρ€ΡƒΠ·ΠΊΠ° ΠΈΠ·ΡƒΡ‡Π΅Π½Π° Π² Π½Π°Π·Π²Π°Π½Π½Ρ‹Ρ… Ρ‚Ρ€Π΅Ρ… Π³Ρ€ΡƒΠΏΠΏΠ°Ρ… ΠΏΠΎ ΡƒΡ€ΠΎΠ²Π½ΡŽ систоличСского ΠΈ диастоличСского Π°Ρ€Ρ‚Π΅Ρ€ΠΈΠ°Π»ΡŒΠ½ΠΎΠ³ΠΎ давлСния, ΠΎΠ±Ρ‰Π΅Π³ΠΎ холСстСрина, Ρ‚Ρ€ΠΈΠ³Π»ΠΈΡ†Π΅Ρ€ΠΈΠ΄ΠΎΠ², Π»ΠΈΠΏΠΎΠΏΡ€ΠΎΡ‚Π΅ΠΈΠ΄ΠΎΠ² высокой ΠΈ Π½ΠΈΠ·ΠΊΠΎΠΉ плотности, Π³Π»ΡŽΠΊΠΎΠ·Ρ‹, Π°Π»ΡŒΠ±ΡƒΠΌΠΈΠ½ΠΎΠ² ΠΈ Π²Π΅Π»ΠΈΡ‡ΠΈΠ½Π΅ окруТности Ρ‚Π°Π»ΠΈΠΈ. Π Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹. УстановлСна статистичСски Π·Π½Π°Ρ‡ΠΈΠΌΠΎ ΠΏΡ€Π΅Π²Ρ‹ΡˆΠ°ΡŽΡ‰Π°Ρ Π²Π΅Π»ΠΈΡ‡ΠΈΠ½Π° аллостатичСской Π½Π°Π³Ρ€ΡƒΠ·ΠΊΠΈ Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ ΠΏΠΎΠΆΠΈΠ»ΠΎΠ³ΠΎ возраста с Ρ€Π°ΠΊΠΎΠΌ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ (4,3 Β± 0,3 Π±Π°Π»Π»Π°) ΠΏΠΎ ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ с ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΊΠ°ΠΌΠΈ срСднСго возраста с Ρ€Π°ΠΊΠΎΠΌ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ (2,9 Β± 0,2 Π±Π°Π»Π»Π°) (p<0,01). ΠšΡ€ΠΎΠΌΠ΅ Ρ‚ΠΎΠ³ΠΎ, Π²Π΅Π»ΠΈΡ‡ΠΈΠ½Π° аллостатичСской Π½Π°Π³Ρ€ΡƒΠ·ΠΊΠΈ Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ срСднСго возраста с диагностированным Ρ€Π°ΠΊΠΎΠΌ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ достовСрно Π²Ρ‹ΡˆΠ΅ (2,7 Β± 0,2 Π±Π°Π»Π»Π°), Ρ‡Π΅ΠΌ срСди ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ Ρ‚ΠΎΠ³ΠΎ ΠΆΠ΅ возраста Π±Π΅Π· новообразования – 1,6 Β± 0,1 Π±Π°Π»Π»Π°. Аналогичная Π·Π°ΠΊΠΎΠ½ΠΎΠΌΠ΅Ρ€Π½ΠΎΡΡ‚ΡŒ установлСна ΠΈ Π² Π³Ρ€ΡƒΠΏΠΏΠ΅ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ ΠΏΠΎΠΆΠΈΠ»ΠΎΠ³ΠΎ возраста, срСди ΠΊΠΎΡ‚ΠΎΡ€Ρ‹Ρ… ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΡŒ аллостатичСской Π½Π°Π³Ρ€ΡƒΠ·ΠΊΠΈ сущСствСнно Π²Ρ‹ΡˆΠ΅ Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ с Π½Π°Π»ΠΈΡ‡ΠΈΠ΅ΠΌ Ρ€Π°ΠΊΠ° ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ (4,3 Β± 0,3 Π±Π°Π»Π»Π°), Ρ‡Π΅ΠΌ ΠΏΡ€ΠΈ Π΅Π³ΠΎ отсутствии – 2,9 Β± 0,2 Π±Π°Π»Π»Π° (Ρ€<0,001). НаиболСС сущСствСнно ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΊΠΈ 60–74 Π»Π΅Ρ‚ с Ρ€Π°ΠΊΠΎΠΌ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ ΠΎΡ‚Π»ΠΈΡ‡Π°ΡŽΡ‚ΡΡ ΠΎΡ‚ возрастного контроля ΠΏΠΎ Ρ‚Π°ΠΊΠΈΠΌ показатСлям аллостатичСской Π½Π°Π³Ρ€ΡƒΠ·ΠΊΠΈ, ΠΊΠ°ΠΊ ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ ΠΎΠ±Ρ‰Π΅Π³ΠΎ холСстСрина – 5,8 Β± 1,3 ммоль/Π» ΠΏΡ€ΠΎΡ‚ΠΈΠ² 4,0 Β± 0,8 ммоль/Π», Π°Π»ΡŒΠ±ΡƒΠΌΠΈΠ½ΠΎΠ² 45,1 Β± 7,4 % ΠΏΡ€ΠΎΡ‚ΠΈΠ² 61,4 Β± 7,6 % соотвСтствСнно. БтатистичСски Π·Π½Π°Ρ‡ΠΈΠΌΡ‹Π΅ различия Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ ΠΏΠΎΠΆΠΈΠ»ΠΎΠ³ΠΎ возраста с Ρ€Π°ΠΊΠΎΠΌ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ ΠΏΠΎ ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ с возрастным ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»Π΅ΠΌ (Π±Π΅Π· Ρ€Π°ΠΊΠ° ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹) выявлСны Ρ‚Π°ΠΊΠΆΠ΅ ΠΏΠΎ Ρ‚Π°ΠΊΠΈΠΌ Π±ΠΈΠΎΠΌΠ°Ρ€ΠΊΠ΅Ρ€Π°ΠΌ аллостатичСской Π½Π°Π³Ρ€ΡƒΠ·ΠΊΠΈ, ΠΊΠ°ΠΊ систоличСскоС Π°Ρ€Ρ‚Π΅Ρ€ΠΈΠ°Π»ΡŒΠ½ΠΎΠ΅ Π΄Π°Π²Π»Π΅Π½ΠΈΠ΅, диастоличСскоС Π°Ρ€Ρ‚Π΅Ρ€ΠΈΠ°Π»ΡŒΠ½ΠΎΠ΅ Π΄Π°Π²Π»Π΅Π½ΠΈΠ΅, ΡƒΡ€ΠΎΠ²Π΅Π½ΡŒ Π² ΠΊΡ€ΠΎΠ²ΠΈ Ρ‚Ρ€ΠΈΠ³Π»ΠΈΡ†Π΅Ρ€ΠΈΠ΄ΠΎΠ² ΠΈ Π³Π»ΡŽΠΊΠΎΠ·Ρ‹, ΠΎΠΊΡ€ΡƒΠΆΠ½ΠΎΡΡ‚ΡŒ Ρ‚Π°Π»ΠΈΠΈ. Π‘ΠΎΠ΄Π΅Ρ€ΠΆΠ°Π½ΠΈΠ΅ Ρ‚Ρ€ΠΈΠ³Π»ΠΈΡ†Π΅Ρ€ΠΈΠ΄ΠΎΠ² Π² ΠΊΡ€ΠΎΠ²ΠΈ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ 60–74 Π»Π΅Ρ‚ с Ρ€Π°ΠΊΠΎΠΌ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹ Π² 1,8 Ρ€Π°Π·Π° Π²Ρ‹ΡˆΠ΅, Ρ‡Π΅ΠΌ Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ Π°Π½Π°Π»ΠΎΠ³ΠΈΡ‡Π½ΠΎΠ³ΠΎ возраста с отсутствиСм новообразования (Ρ€<0,001). Π£Ρ€ΠΎΠ²Π΅Π½ΡŒ Π³Π»ΡŽΠΊΠΎΠ·Ρ‹ Π² ΠΊΡ€ΠΎΠ²ΠΈ Π² сравниваСмых Π³Ρ€ΡƒΠΏΠΏΠ°Ρ… ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ достовСрно Π²Ρ‹ΡˆΠ΅ Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠΊ с Ρ€Π°ΠΊΠΎΠΌ ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹, ΠΎΠ½ составляСт 5,8 Β± 1,2 Π³/Π» ΠΏΡ€ΠΎΡ‚ΠΈΠ² 4,4 Β± 1,1 Π³/Π» Π² возрастном ΠΊΠΎΠ½Ρ‚Ρ€ΠΎΠ»Π΅ (Ρ€<0,01). Π’Ρ‹Π²ΠΎΠ΄Ρ‹. ΠΠ»Π»ΠΎΡΡ‚Π°Ρ‚ΠΈΡ‡Π΅ΡΠΊΡƒΡŽ Π½Π°Π³Ρ€ΡƒΠ·ΠΊΡƒ ΠΈ Π΅Π΅ ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ слСдуСт ΠΈΡΠΏΠΎΠ»ΡŒΠ·ΠΎΠ²Π°Ρ‚ΡŒ Π² качСствС Π±ΠΈΠΎΠΌΠ°Ρ€ΠΊΠ΅Ρ€ΠΎΠ² ΠΏΠΎΠ²Ρ‹ΡˆΠ΅Π½Π½ΠΎΠ³ΠΎ риска развития Ρ€Π°ΠΊΠ° ΠΌΠΎΠ»ΠΎΡ‡Π½ΠΎΠΉ ΠΆΠ΅Π»Π΅Π·Ρ‹

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    It has been substantiated that development of the Arctic should be regarded as a large-scale and long-term investment in the maintenance of the resource potential of Russia being the exclusive owner of the resource potential of the global economy for a long time. A number of scientifically based military and political, socio-economic, organizational and legal measures to protect the national interests of Russia in the Arctic as well as the development of the Arctic sea communications taking into account trends in the global economy have been recommended
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