Upaya Mengembangkan Kreativitas Anak Melalui Bermain Balok Pada Anak Kelompok B Di TK Geneng Ii Gatak, Sukoharjo Tahun Ajaran 2013/2014

Penelitian ini bertujuan untuk mengembangkan kreativitas anak melalui bermain balok pada anak kelompok B di TK Geneng II Gatak, Sukoharjo Tahun Ajaran 2013/2014. Penelitian ini dilaksanakan dengan menggunakan media balok dengan subyak 30 anak. Jenis penelitian ini adalah Penelitian Tindakan Kelas (PTK), teknik pengumpulan data menggunakan metode observasi, catatan lapangan, dan dokumentasi. Observasi adalah mengamati kemampuan kreativitas anak mulai dari sebelum ada tindakan, pada saat proses pembelajaran setelah ada tindakan, hingga pada akhir proses pembelajaran. Catatan lapangan dilakukan untuk mengetahui proses kegiatan pembelajaran bermain balok yang dilakukan guru dan respon anak saat guru menyampaikan kegiatan pembelajaran pada anak kelompok B di TK Genen II Gatak, Sukoharjo, sedangkan dokumentasi digunakan untuk melihat keaktifan anak saat kegiatan bermain balok. Analisis data yang digunakan adalah deskritif komparatif yaitu perbandingan hasil prosentase pencapaian setiap anak dengan skor maksimum yang telah ditentukan melalui siklus-siklus. Berdasarkan hasil perhitungan tiap siklus tindakan pengembangan kreativitas melalui media balok diperoleh hasil pada sebelum dilakukan tindakan 35,23%, siklus I mencapai 48,44%, siklus II mencapai 67%, siklus III mencapai 81,32%. Dengan demikian upaya mengembangkan kreativitas anak pada anak kelompok B di TK Geneng II Gatak, Sukoharjo Tahun Ajaran 2013/2014 dikatakan berhasil karena hasil pada siklus III mencapai 81,32% melebihi target keberhasilan yaitu 75%

Testing the diffusion hypothesis as a mechanism of self-healing in Disperse orange 11 doped in PMMA

In this work, we show that reversible photodegradation of Disperse Orange 11 doped in PMMA is not due to dye diffusion - a common phenomenon observed in many dye-doped polymers. The change in linear absorbance due to photodegradation of the material shows an isobestic point, which is consistent with the formation of a quasi-stable damaged species. Spatially-resolved amplified spontaneous emission and fluorescence, both related to the population density, are measured by scanning the pump beam over a burn mark. A numerical model of the time evolution of the population density due to diffusion is inconsistent with the experimental data suggesting that diffusion is not responsible.Comment: 5 pages, 6 figure

The role of ribonucleases in regulating global mRNA levels in the model organism Thermus thermophilus HB8

BACKGROUND: RNA metabolism, including RNA synthesis and RNA degradation, is one of the most conserved biological systems and has been intensively studied; however, the degradation network of ribonucleases (RNases) and RNA substrates is not fully understood. RESULTS: The genome of the extreme thermophile, Thermus thermophilus HB8 includes 15 genes that encode RNases or putative RNases. Using DNA microarray analyses, we examined the effects of disruption of each RNase on mRNA abundance. Disruption of the genes encoding RNase J, RecJ-like protein and RNase P could not be isolated, indicating that these RNases are essential for cell viability. Disruption of the TTHA0252 gene, which was not previously considered to be involved in mRNA degradation, affected mRNA abundance, as did disruption of the putative RNases, YbeY and PhoH-like proteins, suggesting that they have RNase activity. The effects on mRNA abundance of disruption of several RNase genes were dependent on the phase of cell growth. Disruption of the RNase Y and RNase HII genes affected mRNA levels only during the log phase, whereas disruption of the PhoH-like gene affected mRNA levels only during the stationary phase. Moreover, disruption of the RNase R and PNPase genes had a greater impact on mRNA abundance during the stationary phase than the log phase, whereas the opposite was true for the TTHA0252 gene disruptant. Similar changes in mRNA levels were observed after disruption of YbeY or PhoH-like genes. The changes in mRNA levels in the bacterial Argonaute disruptant were similar to those in the RNase HI and RNase HII gene disruptants, suggesting that bacterial Argonaute is a functional homolog of RNase H. CONCLUSION: This study suggests that T. thermophilus HB8 has 13 functional RNases and that each RNase has a different function in the cell. The putative RNases, TTHA0252, YbeY and PhoH-like proteins, are suggested to have RNase activity and to be involved in mRNA degradation. In addition, PhoH-like and YbeY proteins may act cooperatively in the stationary phase. This study also suggests that endo-RNases function mainly during the log phase, whereas exo-RNases function mainly during the stationary phase. RNase HI and RNase HII may have similar substrate selectivity

Successful Treatment of Epilepsy by Resection of Periventricular Nodular Heterotopia

We report on a case of successful surgical treatment of drug-resistant epilepsy associated with a solitary lesion of periventricular nodular heterotopia (PNH). In the reported patient, intracranial ictal electroencephalography disclosed that seizures did not originate from the heterotopic nodules. However, the seizures were completely suppressed by lesionectomy of PNH alone. Epileptogenesis associated with PNH likely involves a very complex network between PNH and the surrounding cortex, and the disruption of this network may be an effective means of curing intractable, PNH-associated epilepsy

Significance of High-frequency Electrical Brain Activity

　Electroencephalogram (EEG) data include broadband electrical brain activity ranging from infra-slow bands (200 / 250 Hz, respectively) are particularly of note due to their very close relationship to epileptogenicity, with the possibility that they could function as a surrogate biomarker of epileptogenicity. In contrast, physiological high-frequency activity plays an important role in higher brain functions, and the differentiation between pathological / epileptic and physiological HFOs is a critical issue, especially in epilepsy surgery. HFOs were initially recorded with intracranial electrodes in patients with intractable epilepsy as part of a long-term invasive seizure monitoring study. However, fast oscillations (FOs) in the ripple and gamma bands (40-80 Hz) are now noninvasively detected by scalp EEG and magnetoencephalography, and thus the scope of studies on HFOs /FOs is rapidly expanding