Controversies regarding mobilisation and rehabilitation following acute spinal cord injury

Spinal cord injury is a debilitating condition associated with significant physical and emotional burden for the patients and families involved. Despite advances in care of patients following spinal cord injury, rehabilitation following injury remains an underfunded area of research that is in need of significant change. Although bed rest has been suggested to improve spinal cord perfusion after acute cord injury, there is no data to suggest that long periods of bed rest following spinal cord injury (in the absence of haemodynamic or biomechanical instability) leads to better outcome. Despite paucity of evidence, prolonged flat bed rest is still practiced in many spinal cord injury rehabilitation units across United Kingdom with no consensus on timing of mobilisation. Here we review some of the controversies on mobilisation and rehabilitation following spinal cord injury with the aim to emphasise on the benefits of early mobilisation following spinal cord injury and to challenge the old practice of long periods of flat bed rest

Concept note : a democratisation programme in Georgia

A technical report identifying optimal ways of engagement with the Georgian civil society to promote democracy and human rights as part of development programmes funded by DANIDA - the development arm of the Ministry of Foreign Affairs of Denmark

Concept note : a democratisation programme in Ukraine

A technical report on field research in Ukraine identifying the most promising areas in the sphere of the media and civil society for deployment of DANIDA resources in future development and democratisaton programmes funded by the Danish Foreign Ministry

In vitro and in vivo assessment of free radical scavenging and antioxidant activities of Veronica persica Poir

With the appearance of new disorders along with inability of some conventional therapies for the treatment of diseases without any side effects, the discovery of safe and efficient therapeutic agents is of utmost importance in the medical area. In this context, medicinal plants as promising therapeutic candidates can provide a reliable and efficient profile. Since free radicals are at the center of various disorder pathways, reducing their production or complete removal of these chemical species could be advantageous for prevention and treatment of many diseases. In this experiment, free radical scavenging and antioxidant activities of Veronica persica Poir., a known medicinal plant, were evaluated using in vitro and in vivo assays. Chemical characterization results showed a high phenolic content in the V. persica methanol extract. In addition, in vitro assays including DPPH radical-scavenging assay, nitric oxide-scavenging activity assay, hydrogen peroxide scavenging test and bleomycin-dependent DNA damage test revealed significant antioxidant power and radical scavenging capacity of this plant. In accordance, in vivo experiments showed inhibitory effects of the methanol extract on lipid peroxidation, a main cause of cell damage. Our findings revealed the promising potential of this plant in reducing free radicals through different pathways. Moreover, our data suggested a correlation between the high phenolic content of the V. persica extract and its free radical scavenging and antioxidant activities

Integration of Digital Dentistry into a Predoctoral Implant Program: Program Description, Rationale, and Utilization Trends

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/153697/1/jddjde017050.pd