10 research outputs found

    Semi-automatic algorithm for construction of the left ventricular area variation curve over a complete cardiac cycle

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    <p>Abstract</p> <p>Background</p> <p>Two-dimensional echocardiography (2D-echo) allows the evaluation of cardiac structures and their movements. A wide range of clinical diagnoses are based on the performance of the left ventricle. The evaluation of myocardial function is typically performed by manual segmentation of the ventricular cavity in a series of dynamic images. This process is laborious and operator dependent. The automatic segmentation of the left ventricle in 4-chamber long-axis images during diastole is troublesome, because of the opening of the mitral valve.</p> <p>Methods</p> <p>This work presents a method for segmentation of the left ventricle in dynamic 2D-echo 4-chamber long-axis images over the complete cardiac cycle. The proposed algorithm is based on classic image processing techniques, including time-averaging and wavelet-based denoising, edge enhancement filtering, morphological operations, homotopy modification, and watershed segmentation. The proposed method is semi-automatic, requiring a single user intervention for identification of the position of the mitral valve in the first temporal frame of the video sequence. Image segmentation is performed on a set of dynamic 2D-echo images collected from an examination covering two consecutive cardiac cycles.</p> <p>Results</p> <p>The proposed method is demonstrated and evaluated on twelve healthy volunteers. The results are quantitatively evaluated using four different metrics, in a comparison with contours manually segmented by a specialist, and with four alternative methods from the literature. The method's intra- and inter-operator variabilities are also evaluated.</p> <p>Conclusions</p> <p>The proposed method allows the automatic construction of the area variation curve of the left ventricle corresponding to a complete cardiac cycle. This may potentially be used for the identification of several clinical parameters, including the area variation fraction. This parameter could potentially be used for evaluating the global systolic function of the left ventricle.</p

    Effects of Biofeedback in Preventing Urinary Incontinence and Erectile Dysfunction after Radical Prostatectomy

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    In this study, we present a biofeedback method for the strengthening of perineal muscles during the preoperative procedures for radical prostatectomy, and we evaluate this technique as a prevention measure against complications such as urinary incontinence (UI) and erectile dysfunction (ED), which affect prostatectomy patients after surgery. In the experimental protocol, the patients performed specific exercises with the help of a device that provided the patient with visual biofeedback, based on a plot of the anal pressure. For the experimental protocol, we selected 20 male patients, with an average age of 64.0 years, and submitted them to ten therapeutic sessions each. A control group consisting of 32 men with an average age of 66.3 years, who were treated with the same surgical procedure but not with the preoperative procedures, also took part in the experiment. To evaluate UI and ED after the surgery in both control and experimental groups, we used two validated questionnaires—to assess UI, we used the King’s Health Questionnaire (KHQ) and, for ED, we used the International Index of Erectile Function (IIEF-5) Questionnaire. We compared the variables associated with UI and ED after the surgery for the control and experimental groups. The occurrence of UI after radical prostatectomy in the control group (100% of the patients) was higher than that for the experimental group (5% of the patients), with p &lt; 0.0001. Likewise, the occurrence of erectile dysfunction after prostatectomy in the control group (48.6% of the patients) was higher than that for the experimental group (5% of the patients), with p &lt; 0.0001. The number of nocturia events also decreased as a consequence of the intervention (p &lt; 0.0001), as did the number of disposable underwear units for urinary incontinence (p &lt; 0.0001). Furthermore, we compared, only for the experimental group, the anal pressure before the biofeedback intervention and after the surgery, and we verified that the anal pressure after surgery was significantly higher (p &lt; 0.0001). The results strongly suggest that the preoperative biofeedback procedure was effective in decreasing urinary incontinence and erectile dysfunction after radical prostatectomy. As future work, we intend to extend this analysis for larger samples and considering a broader age range

    Analysis of the heat propagation during cardiac ablation with cooling of the esophageal wall : a bidimensional computational modeling

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    Atrial fibrillation (AF) is a cardiac arrhythmia that affects around 33 million people worldwide. A standard form of treatment for AF is cardiac ablation with the radiofrequency catheter (RFCA). RFCA generates heat through the ablation electrode, and this process can cause severe lesions in the atrial and esophageal tissues. This work presents a two-dimensional computational model that uses geometry and boundary conditions that approximate cardiac ablation conditions with a non-irrigated catheter. The paper’s objective is to simulate the RFCA and analyze the heat propagation during cardiac ablation when the esophageal wall is cooled down. The esophagus, the connective tissue, and the heart wall were simulated, assuming laminar blood flow in the heart wall. The simulated electrode temperatures were 60, 70, and 80 °C for 60 seconds with constant peak voltage. The cooling temperature was 0 °C. The results showed that cooling decreases the temperature between tissues. The temperature in connective-cardiac tissue dropped by approximately 6.51%. In the esophageal-connective tissue, the temperature decreased by about 28.22%. In all cases, there was also a slowing in temperature increase, which can help prevent tissue damage. The results suggest that the method has significant potential for improving the safety of RFCA

    Semi-automatic detection of the left ventricular border

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    Two semi-automatic methods for the detection of the left ventricular border in two-dimensional short axis echocardiographic images are presented and compared. In these methods, the left ventricular area variation curve is calculated during a complete cardiac cycle after the segmentation of several frames. This allows the evaluation of the cardiovascular dynamics and the identification of important clinical parameters. The algorithms are proposed as several independent modules. The results are validated through the comparison between the semi-automatic continuous boundaries and manuals boundaries sketched by a medical specialist
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