A prospective study to evaluate the role of routine early third trimester ultrasound in the diagnosis of intrauterine growth restriction and prediction of adverse perinatal outcome using color Doppler

Background: Intrauterine growth restriction (IUGR) is a major and silent cause of perinatal morbidity and mortality. Rate of IUGR in developing countries is 6 times higher than that of developed countries. 14 to 20 million infants are affected with IUGR in developing countries annually. The highest incidence is found in south central Asia (33%) and India (21%). Aim of study was to evaluate the role of early 3rd trimester ultrasound in diagnosis and role of color Doppler in prediction of adverse perinatal outcome in IUGR.Methods: A prospective case-control study was conducted on 720 women admitted in GMH Rewa for one year. 360 antenatal cases diagnosed as IUGR on ultrasound were taken as study group, same number of non IUGR cases were taken as control. Study cases were followed with Doppler. The umbilical artery pulsatility index (UA PI), middle cerebral artery pulsatility index (MCA PI) and cerebro-placental ratio were calculated and the results were analysed.Results: Inferences drawn from the study were: rate of caesarean section was significantly higher (31%) in study group, perinatal outcome was poor in more number of cases (10.8%) in study group than the control group (3.4%), and the sensitivity and specificity of cerebroplacental ratio was more reliable indicator in comparison to that of UA PI and MCA PI in prediction of adverse perinatal outcome.Conclusions: Looking at the high burden of IUGR cases in our country and its adverse effects on perinatal outcome, if early third trimester ultrasound is made mandatory for all pregnant women, most of the IUGR cases can be detected and managed timely and perinatal outcome can be significantly improved

A retrospective study of the comparison of maternal outcomes in in-vitro-fertilization pregnancy versus spontaneous conception

Background: The adverse maternal outcomes of newer technology of IVF have not been studied so far, especially in India.  The aim of the study was to compare maternal near miss and mortality between IVF-conceived and spontaneously conceived pregnancies, at a tertiary-level hospital, in Delhi. Methods: We conducted a retrospective cohort study from 2018-2020. The demographic, obstetrics, past history, obstetric-related morbidity, mode of delivery, details of maternal near miss and mortality, and their reasons were recorded. Similar data from spontaneous conceptions were compiled. Comparison of maternal characteristics was tested using chi-square test, p<0.05 was considered significant.  Results: Mean age of women in the study group was 33.16±5.58 years and in controls was 26.16±4.28 years. The risk of multiple pregnancy (58.5% versus 2%, p<0.0001), pre-eclampsia (62.8% versus 17.1%, p<0.0001), gestational diabetes mellitus (23.5% versus 14.2%, p=0.0493), intrahepatic cholestasis of pregnancy (32.8% versus 10%, p<0.0001), antepartum haemorrhage (12.1% versus 2.85%, p=0.0066), preterm deliveries (66.4% versus 5.7%, <0.0001), and maternal near miss (12.8% versus 0.7%, OR 20.50, 95% CI-2.6979 to 155.8916, p=0.0035) were much higher in the study group as compared to the control group and was statistically significant. The odds of maternal mortality were 4.0882, 95% CI 0.4512 to 37.0465, p=0.2105 in the study group as compared to the control group. Conclusions: There is a need to counsel couples wanting to conceive with IVF about not just the procedure and success rates of it, but also the potential for pregnancy complications

Decline of Professional Ethics in Indian Education System

Recently there is an increasing awareness and more importantly, an increasing interest in the field of professional ethics. In fact, perhaps there has not been any time in the history of education development where the concepts and an understanding of the nature of professional ethics have been so urgently needed. The popular concept that if it is education then it will be ethical and if it is ethical, it can be only education and this concept has been declined in last few decades. In higher and technical education the ethical consideration has lost its value and place, in real life ethics cannot be learned by books or by any other source of information, therefore it is really difficult to find ethical people around us, whereas it is very easy to find large number of unethical managers, bureaucrats, educationalist, corporate heads, politicians and elected representatives. This paper describes about ethics, professional ethics and its importance, professional code of ethics for teachers, factors affecting ethical standards in education, lack of ethical education in teachers training programmes and need to re-introduce value based education, spiritual education, ethical education and need based education in the curriculum which should deal with increase in human values, ethical values, rational thinking, learning, research and moral development in education system. DOI: 10.17762/ijritcc2321-8169.15078

HMOS: Head Control Mouse Person with Disability

This paper presents an idea to build a human machine interface for disable persons. The purposed idea is very economical and useful for those disable persons who cannot use their hands to control computers.The main focus is to control the mouse through their head movements by using head-tilt sensor and air blow sensor. The system uses dual axis accelerometer based tilt sensor for detecting the movement of the head which is mounted on the headset and clicking of the mouse is activated by the 2 air blow sensor which are placed near the mouth to detect the left and right click of the mouse from the effect of the air blow in to the sensors. Since the device relies only on the user?s head and air blow, so it can be used easily without requiring too much energy neither in the head movement nor in the air blow for clicking. This system encourage the disable person to start their independent professional life

A Survey on Android Malware Detection

Malwares are spreading around the world and infecting not only the end users but also large organizations and service providers. Android operating system seems to have attracted the most attention from Malicious code writer due to its popularity. Earlier, Signature based detection techniques were used to detect unknown malwares. But it was insufficient because these techniques were not able to detect unknown malwares (0-day attack). To analyze the malwares, static and dynamic techniques are used. Static analysis has advantage of being undetectable, as malware cannot modify its behavior during analysis. Despite number of detections and analysis techniques are in place, high detection accuracy of new malwares are still a critical issue. This survey paper highlights the existing detection and existing analysis methods used for the android Malicious code

Low Power Design for D Flip Flop

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EST-SSRs Provide a Good Measure of Genetic Diversity for Improvement of Gum Content in Cluster Bean

Cyamopsis tetragonoloba (L.) Taub., commonly known as guar is an important multipurpose arid leguminous crop of India, mainly cultivated in north-western parts of India. The pods of the guar plant grow in clusters giving guar the common name of clusterbean. It is mainly grown for feed, green fodder, vegetable and green manuring. Its seeds are also an important source of galactomannan (guar gum) which is used as a food ingredient and more recently as a neutraceutical. Guar gum is also having pharmaceutical importance and found to be effective in osteoarthritis, as artificial cervical mucus and for anticancer medicine in the treatment of colorectal cancer. Particularly in 2012, world demand for guar gum has skyrocketed and the price of guar has increased by approximately 230 per cent and even more, mainly because of increased oilfield shale gas demand. As a consequence, there has been a 75 per cent jump in exports from India, the largest guar producing country (Gresta et al., 2013) due to which India’s much neglected and little-known galactomannan became its biggest agricultural item of export. To fulfill all these purposes, the increasing demand of the guar seeds cannot be compensated by present resources. Therefore, new varieties with higher gum content are urgently needed. For this, knowledge of genetic diversity among the varieties has immense importance for plant breeders. Larger variability in the initial breeding material ensures better chances of producing new desired forms of a crop (Pathak et al., 2011). Molecular markers offer a promising tool for plant breeding efforts. SSRs are highly valued molecular markers for studying genetic diversity in crop plants. But unfortunately, clusterbean is a genomically poor crop as no genomic SSRs have been developed. Literature available on the nature and magnitude of diversity in clusterbean indicates that the studies of this kind are scanty and not properly documented. Studies were therefore, required to assess the extent of genetic variability in association with the galactomannan content using reliable EST-SSRs

Comparison of the various diagnostic criteria used in polycystic ovary syndrome

Background: Polycystic Ovary Syndrome (PCOS) represents one of the major causes of infertility in women. Various criteria are set to diagnose PCOS, some over diagnose and some underdiagnose it. The objective of the study was to compare the various criteria used for the diagnosis of PCOS: NIH 1990 criteria, Rotterdam 2003 criteria and AE-PCOS Society 2006 criteria.Methods: This was a cross-sectional study conducted over a period of one year. Patients with suspicion of PCOS were selected. After complete history and examination, blood samples were collected and androgen levels were measured. They were labeled as PCOS based on their fulfillment of the criteria as per Rotterdam, NIH and AE-PCOS Society.Data was analysed and conclusions drawn.Results: Of the participants, 25.7%, 28.5%, and 62.8% were diagnosed with PCOS using NIH, AE-PCOS Society, and Rotterdam criteria, respectively. Phenotypes that included hyperandrogenism and/or hyperandrogenemia as part of their criteria showed increase in values of DHEAS and S. testoterone as compared to the normoandrogenic phenotype included in only the Rotterdam criteria.Conclusions: It is crucial to establish the diagnostic criteria for PCOS and initiate early treatment as this may play a role in the prevention of metabolic and cardiovascular diseases

Unilateral macular branch retinal vein occlusion in a healthy Indian woman following coronavirus disease vaccination: a case report and comprehensive literature review

Background: The coronavirus disease (COVID-19) vaccines exert ocular adverse effects, including episcleritis, scleritis, anterior and recurrent uveitis, acute macular neuroretinopathy, paracentral acute middle maculopathy, ophthalmic vein thrombosis, Graves’ disease, arteritic anterior ischemic optic neuropathy,  non-arteritic anterior ischemic optic neuropathy, central serous chorioretinopathy, Vogt-Koyanagi-Harada disease, multifocal choroiditis, cranial nerve palsies such as facial or abducens nerve palsy, acute zonal occult outer retinopathy, acute zoster ophthalmicus following re-activation of the varicella-zoster virus, acute retinal necrosis, and multiple evanescent white dot syndrome. In this case report, we explored the possibility of macular branch retinal vein occlusion and its association with COVID-19 vaccination. Case Presentation: A 44-year-old healthy woman presented with unilateral nonprogressive blurring of vision in the right eye (OD). Her best-corrected distance visual acuity (BCDVA) in OD was 20 / 40. The anterior-segment evaluation was normal. Fundus evaluation of the OD revealed macular branch vein occlusion. She had a history of COVID-19 vaccination within 1 month. The interleukin-6 level was elevated six folds to 30.5 pg / mL. However, COVID-19 immunoglobulin G (IgG) antibodies were negative. Infective etiologies, such as tuberculosis and dengue, were ruled out. Spectral-domain optical coherence tomography (SD-OCT) of the OD showed hyperreflective dots in the posterior vitreous, inner retinal swelling, and cystoid changes in the macula. The maximum central macular thickness was 486 mm. A single dose of bevacizumab was administered at OD intravitreally. At the final follow-up 2.5 months later, her BCDVA had improved to 20 / 20 OD. Fundus evaluation revealed fewer retinal hemorrhages and cotton wool spots. SD-OCT of the OD showed a normal foveal contour and absence of cystoid spaces. Her maximum central macular thickness was 236 mm. Conclusions: A temporal effect of vein occlusion secondary to COVISHIELD™ vaccination may occur in the absence of systemic risk factors. The interleukin-6 level was elevated, and the remaining blood test results were within normal limits. Since this is a case report, it is limited by the absence of strong evidence to prove this causal relationship between macular branch retinal vein occlusion and the specific brand of COVID-19 vaccination