An Assessment of Sedentary Pastoralists Perception of Climate Change in and around Forest and Grazing Reserves of Semi-arid Areas of Northern, Nigeria

The study was aimed at assessing the Sedentary Pastoralist perception of Climate Change in and around Grazing and Forest Reserves in Semi-Arid Area of Northern, Nigeria: A total of 125 questionnaires were administered in five selected grazing and forest reserves of the study area using an accidental sampling method. The data for this study were generated using questionnaire administration and interview with community leaders (Ardos). The data generated were analyzed using descriptive statistics in formof percentage and narrative form. The study shows that 42.20% of the respondents are of the view that deforestation and overcultivation were the major factors influencing climate change. However 36% of the respondents further confirmed that the increase in the emergence of dry years was the major indicator of climate change, followed by the late onset of rainfall with 27.2%. Furthermore, 44% and 40% of the respondents admitted that climate change has significantly and partially affected water availability while 52% and 41.6% reported having noticed that climate change has significantly and partially affected the availability of pasture resources. This study concluded that human environmental intervention such as deforestation, over-cultivation among others were major factors influencing the rate of climate change in the area. The study further recommended that pastoralist should adopt to develop more resilient practices locallyto cope with the impact of climate change, provision of solar and wind-powered boreholes as alternative waters sources to the sedentary pastoralists as well as the need for the desilting of degraded surface water bodies to make them more productive. Keywords: Sedentary Pastoralist, Climate Change, Forest/Grazing Reserves, Semi-arid

Gaussian beam divergence using paraxial approximation

Gaussian beam intensity follows a normal distribution curve in free space. As it propagates, the divergence and the width increase with distance. Using paraxial approximation, the effect of the distance on the intensity, width, radius of curvature and divergence was investigated. Matlab software was used for characteristics parameters calculation. The divergence angle range (26.67o≤ θ ≤35.85o) was obtained at a distance between 3mm and 4mm, and compared with the divergence angle range (43o≤ θ ≤53o) obtained experimentally for the distance between 3mm and 4.5mm. The result obtained in this work indicates smaller angles of divergence that can produce a better beam quality and intensity. Finally, this will serve as a great importance for application such as pointing, free space optical communication etc.Keyword: Gaussian beam, Paraxial approximation, Beam divergence, Normal distribution curve

The effect of water solubles on Kelvin effects of the Maritime Polluted aerosols

In this work microphysical properties of Maritime Polluted aerosols wereextracted from Optical Properties of Aerosols and Clouds (OPAC) after varying the concentrations of water soluble at five different levels. The analytical expressions for the changes in the equilibrium relative humidity (RH), effective radii, effective hygroscopic growth, their magnitudes and fractional changes on the  effects of surface tension (the Kelvin effect) on the ambient aerosols were numerically  analyzed. The expressions were applied to two - one parameter models. It was  discovered that the increase in water soluble concentration caused decreased in the Kelvin effects which implies decrease in surface tension. The numerical analysis of the data showed that to the lowest order error.   Increase in the overestimation of the effective hygroscopic growth and decrease in the overestimation of the effective radii. On  the two models applied, we discovered that the fractional changes in hygroscopic growth increase in overestimation while there is decrease in  overestimation of fractional changes in effective radii. Finally, decrease in the underestimation of the fractional  changes in the equilibrium pressure it was discovered.Keywords: Kelvin effect, effective radius, effective hygroscopic growth, water soluble, ambient Relative Humidity, overestimation

Economic evaluation of shortened, bedaquiline-containing treatment regimens for rifampicin-resistant tuberculosis (STREAM stage 2): a within-trial analysis of a randomised controlled trial

Background The STREAM stage 2 trial assessed two bedaquiline-containing regimens for rifampicin-resistant tuberculosis: a 9-month all-oral regimen and a 6-month regimen containing an injectable drug for the first 2 months. We did a within-trial economic evaluation of these regimens. Methods STREAM stage 2 was an international, phase 3, non-inferiority randomised trial in which participants with rifampicin-resistant tuberculosis were randomly assigned (1:2:2:2) to the 2011 WHO regimen (terminated early), a 9-month injectable-containing regimen (control regimen), a 9-month all-oral regimen with bedaquiline (oral regimen), or a 6-month regimen with bedaquiline and an injectable for the first 2 months (6-month regimen). We prospectively collected direct and indirect costs and health-related quality of life data from trial participants until week 76 of follow-up. Cost-effectiveness of the oral and 6-month regimens versus control was estimated in four countries (oral regimen) and two countries (6-month regimen), using health-related quality of life for cost-utility analysis and trial efficacy for cost-effectiveness analysis. This trial is registered with ISRCTN, ISRCTN18148631. Findings 300 participants were included in the economic analyses (Ethiopia, 61; India, 142; Moldova, 51; Uganda, 46). In the cost-utility analysis, the oral regimen was not cost-effective in Ethiopia, India, Moldova, and Uganda from either a provider or societal perspective. In Moldova, the oral regimen was dominant from a societal perspective. In the cost-effectiveness analysis, the oral regimen was likely to be cost-effective from a provider perspective at willingness-to-pay thresholds per additional favourable outcome of more than US$4500 in Ethiopia,$1900 in India, $3950 in Moldova, and$7900 in Uganda, and from a societal perspective at thresholds of more than $15 900 in Ethiopia,$3150 in India, and $4350 in Uganda, while in Moldova the oral regimen was dominant. In Ethiopia and India, the 6-month regimen would cost tuberculosis programmes and participants less than the control regimen and was highly likely to be cost-effective in both cost-utility analysis and cost-effectiveness analysis. Reducing the bedaquiline price from$1·81 to $1·00 per tablet made the oral regimen cost-effective in the provider-perspective cost-utility analysis in India and Moldova and dominate over the control regimen in the provider-perspective cost-effectiveness analysis in India. Interpretation At current costs, the oral bedaquiline-containing regimen for rifampicin-resistant tuberculosis is unlikely to be cost-effective in many low-income and middle-income countries. The 6-month regimen represents a cost-effective alternative if injectable use for 2 months is acceptable

Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019

Background: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods: 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate age-specific fertility rates for 5-year age groups between ages 15 and 49 years. With extensions to age groups 10–14 and 50–54 years, the total fertility rate (TFR) was then aggregated using the estimated age-specific fertility between ages 10 and 54 years. 7417 sources were used for under-5 mortality estimation and 7355 for adult mortality. ST-GPR was used to synthesise data sources after correction for known biases. Adult mortality was measured as the probability of death between ages 15 and 60 years based on vital registration, sample registration, and sibling histories, and was also estimated using ST-GPR. HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated using a Bayesian hierarchical cohort component model that analysed estimated age-specific fertility and mortality rates along with 1250 censuses and 747 population registry years. We classified location-years into seven categories on the basis of the natural rate of increase in population (calculated by subtracting the crude death rate from the crude birth rate) and the net migration rate. We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. Uncertainty was propagated throughout the demographic estimation process, including fertility, mortality, and population, with 1000 draw-level estimates produced for each metric. Findings: The global TFR decreased from 2•72 (95% uncertainty interval [UI] 2•66–2•79) in 2000 to 2•31 (2•17–2•46) in 2019. Global annual livebirths increased from 134•5 million (131•5–137•8) in 2000 to a peak of 139•6 million (133•0–146•9) in 2016. Global livebirths then declined to 135•3 million (127•2–144•1) in 2019. Of the 204 countries and territories included in this study, in 2019, 102 had a TFR lower than 2•1, which is considered a good approximation of replacement-level fertility. All countries in sub-Saharan Africa had TFRs above replacement level in 2019 and accounted for 27•1% (95% UI 26•4–27•8) of global livebirths. Global life expectancy at birth increased from 67•2 years (95% UI 66•8–67•6) in 2000 to 73•5 years (72•8–74•3) in 2019. The total number of deaths increased from 50•7 million (49•5–51•9) in 2000 to 56•5 million (53•7–59•2) in 2019. Under-5 deaths declined from 9•6 million (9•1–10•3) in 2000 to 5•0 million (4•3–6•0) in 2019. Global population increased by 25•7%, from 6•2 billion (6•0–6•3) in 2000 to 7•7 billion (7•5–8•0) in 2019. In 2019, 34 countries had negative natural rates of increase; in 17 of these, the population declined because immigration was not sufficient to counteract the negative rate of decline. Globally, HALE increased from 58•6 years (56•1–60•8) in 2000 to 63•5 years (60•8–66•1) in 2019. HALE increased in 202 of 204 countries and territories between 2000 and 2019. Interpretation: Over the past 20 years, fertility rates have been dropping steadily and life expectancy has been increasing, with few exceptions. Much of this change follows historical patterns linking social and economic determinants, such as those captured by the GBD Socio-demographic Index, with demographic outcomes. More recently, several countries have experienced a combination of low fertility and stagnating improvement in mortality rates, pushing more populations into the late stages of the demographic transition. Tracking demographic change and the emergence of new patterns will be essential for global health monitoring. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens

Global burden of 87 risk factors in 204 countries and territories, 1990�2019: a systematic analysis for the Global Burden of Disease Study 2019

Background: Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardised and comprehensive assessment of the magnitude of risk factor exposure, relative risk, and attributable burden of disease. Methods: GBD 2019 estimated attributable mortality, years of life lost (YLLs), years of life lived with disability (YLDs), and disability-adjusted life-years (DALYs) for 87 risk factors and combinations of risk factors, at the global level, regionally, and for 204 countries and territories. GBD uses a hierarchical list of risk factors so that specific risk factors (eg, sodium intake), and related aggregates (eg, diet quality), are both evaluated. This method has six analytical steps. (1) We included 560 risk�outcome pairs that met criteria for convincing or probable evidence on the basis of research studies. 12 risk�outcome pairs included in GBD 2017 no longer met inclusion criteria and 47 risk�outcome pairs for risks already included in GBD 2017 were added based on new evidence. (2) Relative risks were estimated as a function of exposure based on published systematic reviews, 81 systematic reviews done for GBD 2019, and meta-regression. (3) Levels of exposure in each age-sex-location-year included in the study were estimated based on all available data sources using spatiotemporal Gaussian process regression, DisMod-MR 2.1, a Bayesian meta-regression method, or alternative methods. (4) We determined, from published trials or cohort studies, the level of exposure associated with minimum risk, called the theoretical minimum risk exposure level. (5) Attributable deaths, YLLs, YLDs, and DALYs were computed by multiplying population attributable fractions (PAFs) by the relevant outcome quantity for each age-sex-location-year. (6) PAFs and attributable burden for combinations of risk factors were estimated taking into account mediation of different risk factors through other risk factors. Across all six analytical steps, 30 652 distinct data sources were used in the analysis. Uncertainty in each step of the analysis was propagated into the final estimates of attributable burden. Exposure levels for dichotomous, polytomous, and continuous risk factors were summarised with use of the summary exposure value to facilitate comparisons over time, across location, and across risks. Because the entire time series from 1990 to 2019 has been re-estimated with use of consistent data and methods, these results supersede previously published GBD estimates of attributable burden. Findings: The largest declines in risk exposure from 2010 to 2019 were among a set of risks that are strongly linked to social and economic development, including household air pollution; unsafe water, sanitation, and handwashing; and child growth failure. Global declines also occurred for tobacco smoking and lead exposure. The largest increases in risk exposure were for ambient particulate matter pollution, drug use, high fasting plasma glucose, and high body-mass index. In 2019, the leading Level 2 risk factor globally for attributable deaths was high systolic blood pressure, which accounted for 10·8 million (95 uncertainty interval UI 9·51�12·1) deaths (19·2% 16·9�21·3 of all deaths in 2019), followed by tobacco (smoked, second-hand, and chewing), which accounted for 8·71 million (8·12�9·31) deaths (15·4% 14·6�16·2 of all deaths in 2019). The leading Level 2 risk factor for attributable DALYs globally in 2019 was child and maternal malnutrition, which largely affects health in the youngest age groups and accounted for 295 million (253�350) DALYs (11·6% 10·3�13·1 of all global DALYs that year). The risk factor burden varied considerably in 2019 between age groups and locations. Among children aged 0�9 years, the three leading detailed risk factors for attributable DALYs were all related to malnutrition. Iron deficiency was the leading risk factor for those aged 10�24 years, alcohol use for those aged 25�49 years, and high systolic blood pressure for those aged 50�74 years and 75 years and older. Interpretation: Overall, the record for reducing exposure to harmful risks over the past three decades is poor. Success with reducing smoking and lead exposure through regulatory policy might point the way for a stronger role for public policy on other risks in addition to continued efforts to provide information on risk factor harm to the general public. Funding: Bill & Melinda Gates Foundation. © 2020 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 licens

Evaluation of chemical composition of raw and processed tropical sickle pod (Senna obtusifolia) seed meal

Abstract. A laboratory analysis was conducted to evaluate the chemical composition of raw and differently processed Senna obtusifolia seed meal. Senna obtusifolia seeds were processed using boiling, soaking, sprouting and fermentation methods respectively. The processed and raw seed meals were milled and the representative seed meal samples were analysed using standard laboratory methods. The results of the chemical analysis revealed that Senna obtusifolia seed meal possessed good nutritional properties (23.40 – 25.90% crude protein and 2.14 – 2.86 MJ/kg metabolizable energy) and has good amino acid profile as an alternative feed source for livestock. However, the raw seed meal contains 378.5, 247.2, 102.0, 248.6 and 190.0 mg/100.0g of tannins, phytates, oxalate, alkaloids and saponins, respectively. The different processing methods were observed to be effective in reducing the level of the antinutrients with fermentation recording the highest reduction levels of 68.25, 66.32, 43.70, 58.07 and 44.30% for tannins, phytates, oxalate, alkaloids and saponins followed by boiling with reduction levels of 66.27, 46.97, 46.97, 47.89, 58.66 and 45.78% for tannins, phytates, oxalate, alkaloids and saponins, respectively. In conclusion, Senna obtusifolia seed can be effectively process for utilization as feed ingredient using fermentation. Feeding trial should be conducted using Senna obtusifolia seed meal to evaluate the feeding value in livestock especially monogastric animal

Haematological and serum biochemical indices of broiler chickens fed raw sickle pod (Senna obtusifolia) seed meal

Abstract. A feeding trial was conducted for sixty three (63) days (9 weeks) to evaluate the effects of feeding raw Senna obtusifolia seed meal (RSOSM) on haematological indices and serum biochemical parameters of broiler chickens. Six experimental diets were compounded for both the starter (23% crude protein - CP) and finisher (20% CP) phases of growth. The diets were formulated to contain 0, 5, 10, 15, 20 and 25% level of raw Senna obtusifolia seed meal replacing roasted soya bean weight for weight in T , T , T , T , T and T respectively. The 0% replacement level (T1) served as the control diet. The broiler 1 2 3 4 5 6, 2 chickens were managed on deep litter pens of 30 birds/2.22 m , weighed and randomly allotted to the six (6) dietary treatments in a randomized complete block design (RCBD). Each treatment group consisted of thirty (30) broiler chicks replicated three times with ten (10) broiler chicks per replicate. Blood samples were collected from the wing vein at the end of the experiment using standard procedure and were analysed for haematological and biochemical profile. The outcome of this study revealed that the haematological indices were not significantly (P>0.05) affected by the dietary treatments. However, the blood chemistry was significantly (P<0.05) affected by the experimental diets. The total protein, albumin, globulin, and some electrolytes components were observed to be significantly (P<0.05) depressed as the level of RSOSM increased in the experimental diets. For instance, total protein was observed to reduce from 6.24g/dl in T1 to 3.6g/dl in T6. Electrolyte constituents such as calcium were similarly observed to reduce from 6.01 mmol/l in T1 to 1.15 mmol/l in T6. The serum enzymes and bilirubin were elevated as the level of RSOSM increases in the experimental diets. Aspartate amino transferase (AST) for instance increased from 8.27U/l in T1 to 23.18 U/l in T6. It can be concluded that incorporation of RSOSM beyond 5% in the diets of broiler chickens has adverse effects on blood parameters especially the biochemical parameters

A survey of haematophagous flies and cattle trypanosomiasis in Ikara and Kubau Local Government Areas, Kaduna State, Nigeria

A survey of species composition and distribution of haematophagous flies as well as occurrence of Trypanosoma species of cattle was conducted between March and August, 2015, at Ikara and Kubau Local Government Areas, Kaduna State, using Biconical and Nzi traps. Twelve traps were placed for 48hrs along four districts in each of the local government areas and harvested every 24hrs. Blood samples from cattle were analyzed for the presence of Trpanosomes using thick, thin Blood smear and Hematocrit centrifugation method. A total of 232 haematophagous and non-haematophagous flies were caught during the study period. Ikara Local Government had a higher occurrence of flies 127(54.7%) than Kubau Local Government 105(45.3%). The occurrence of the haematophagous flies, Stomoxys calcitrans 107(85.3%) had the highest occurrence than Tabanus 9(7.1%) while Glossina had 0(0.0%). The rainy season had 212 flies trapped compared to the dry season with fewer flies. There was a significant association (p&lt;0.05) between flies occurrence and seasons. The cattle sampled were positive for T. vivax and T. brucei. There was no significant association (p&gt;0.05) between the occurrence of Trypanosoma infection in the study area. It is very important to mention that plans should be put in place for the total eradication of these flies and parasite as they could act as vector for the transmission of pathogens that can cause significant health crises in human and animals.Keywords: Haematophagous; flies; trypanosome; Nzi, biconical; Ikara; Kubau; Kaduna State

Laying performance and cost-benefits of feeding brown laying hens with raw or processed tropical sickle pod (Senna obtusifolia) seed meal based-diets

Abstract. . A feeding trial was conducted for 16 weeks to evaluate the effects and cost-benefits of feeding raw or processed Senna obtusifolia (S. obtusifolia) seed meal based-diets on the laying performance of ISA brown laying hens. Six experimental diets were compounded to contain 0% S. obtusifolia seed meal (T1) and 20% each of the raw, boiled, soaked, sprouted and fermented S. obtusifolia seed meals designated as T2, T3, T4, T5 and T6, respectively. One hundred and eighty (180) ISA brown laying hens aged 36 weeks were housed in battery cages (5 birds/0.95m2) and assigned to the six (6) dietary treatments in groups of thirty (30) birds in a completely randomized design. Each replicate cage contains 10 laying hens. Data were collected on feed intake, hen-day egg production (HDEP), hen-house egg production (HHEP), egg weight, egg mass, feed conversion ratio per egg mass, feed cost per kilogram, feed cost per egg mass and mortality. The results indicated that the group of laying hens fed raw S. obtusifolia seed meal based diet recorded the lowest HDEP (52.42%), egg weight (53.08g) and egg mass (2782.45g). Among the hens fed the processed S. obtusifolia seed meal based diets, the laying hens fed the fermented S. obtusifolia seed meal based diet indicated significantly (p<0.05) better HDEP (64.05%), egg weight (58.45g) and egg mass (3743.72g). On economic grounds, the use of raw S. obtusifolia is not cost effective because feed cost per kilogram egg was relatively high (N317.47 or $0.82) in the group of laying hens fed raw S. obtusifolia seed meal based diet. However, the processed S. obtusifolia seed meal based diets showed some economic advantage. In conclusion, 20% of fermented S. obtusifolia seed meal can be incorporated in the diets of laying hens with little or no depreciation in laying performance and economic-benefits