2,302 research outputs found

    Using Migration Monitoring Data to Assess Bird Population Status and Behavior in a Changing Environment

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    Across the world, researchers use migration banding stations to document bird migration and study the phenomenon. In this dissertation, I focus on ways of analyzing bird migration banding data and the utility migrating birds as indicators of ecosystem health that make these monitoring efforts more useful to answering ecological questions and managing migratory species. In Chapter 1, we provide background on hierarchical modeling and an overview of our findings. In Chapter 2, we developed and validated new methods to estimate daily changes in migratory population size while controlling for changes in detectability due to environmental conditions. In Chapter 3, this modeling technique was then employed to evaluate the continental-scale and the local-scale determinants of migratory population size for ten species of migrants using a Key Biscayne, FL site for migratory stopover in the fall. Species showed diverse relationships between abundance and local weather conditions. Wet conditions on the breeding grounds consistently increased migratory onset and dry conditions on the non-breeding grounds from the previous winter consistently reduced population size across all species. In Chapter 4, we looked at how daily changes in migrant density influenced the stopover behavior of seven songbirds at the Key Biscayne stopover site. Density-dependence had positive and negative effects on mass gain across species, the chance of that effect being negative increased with the average daily stopover population size of the species. Density-dependence was hypothesized to be a function of overall migrant abundance at the site, with only highly abundance species showing negative effects. Finally, in Chapter 5 migrating birds are used to tell us about contaminant exposure in their breeding and non-breeding environments. We found higher amount of mercury in fall than the spring and there was evidence that fall mercury exposure was altering migratory behavior. These patterns provide the first evidence that Hg exposure alters migratory physiology in songbirds. Overall, this dissertation suggests that migration monitoring is useful for both basic and applied research and provide a tool for understanding the complicated life cycles of migratory animals

    Pan-cancer analysis reveals cooperativity of both strands of microRNA that regulate tumorigenesis and patient survival

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    Recently, both 5p and 3p miRNA strands are being recognized as functional instead of only one, leaving many miRNA strands uninvestigated. To determine whether both miRNA strands, which have different mRNA-targeting sequences, cooperate to regulate pathways/functions across cancer types, we evaluate genomic, epigenetic, and molecular profiles of \u3e5200 patient samples from 14 different cancers, and RNA interference and CRISPR screens in 290 cancer cell lines. We identify concordantly dysregulated miRNA 5p/3p pairs that coordinately modulate oncogenic pathways and/or cell survival/growth across cancers. Down-regulation of both strands of miR-30a and miR-145 recurrently increased cell cycle pathway genes and significantly reduced patient survival in multiple cancers. Forced expression of all four strands show cooperativity, reducing cell cycle pathways and inhibiting lung cancer cell proliferation and migration. Therefore, we identify miRNA whose 5p/3p strands function together to regulate core tumorigenic processes/pathways and reveal a previously unknown pan-cancer miRNA signature with patient prognostic power

    Job-Related Burnout among Juvenile Probation Officers: Implications for Mental Health Stigma and Competency

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    The high demands and responsibilities of probation work, particularly with juvenile clients, may lead to burnout, which can negatively impact how probation officers work with clients, particularly individuals with behavioral health concerns. Yet, research examining burnout and related outcomes among juvenile probation officers (JPOs) is limited. We surveyed 246 JPOs in a Midwestern state to identify the prevalence, predictors, and potential outcomes of burnout. JPOs reported moderate levels of burnout; about 30% of the sample scored in the high range for emotional exhaustion and cynicism. Contrary to study hypotheses, there were no group-level differences in burnout scores across gender, race/ethnicity, age, or education. In regression models, burnout was predicted by being White (vs. minority), serving in an urban (vs. rural) county, dissatisfaction with department guidelines, job dissatisfaction, viewing job role as more treatment-oriented along the enforcement−treatment continuum, and turnover intention. JPOs with burnout were more likely to endorse mental health stigma and lack of mental health competency to address juvenile clients with behavioral health concerns. Findings suggest burnout prevention and intervention programs should be considered for JPOs to increase job satisfaction, limit job turnover, reduce burnout, and possibly increase effective practices for managing juvenile clients with behavioral health needs

    Strangelets: Who is Looking, and How?

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    It has been over 30 years since the first suggestion that the true ground state of cold hadronic matter might be not nuclear matter but rather strange quark matter (SQM). Ever since, searches for stable SQM have been proceeding in various forms and have observed a handful of interesting events but have neither been able to find compelling evidence for stable strangelets nor to rule out their existence. I will survey the current status and near future of such searches with particular emphasis on the idea of SQM from strange star collisions as part of the cosmic ray flux.Comment: Talk given at International Conference on Strangeness in Quark Matter, 2006. 8 pages. 1 figur

    Understanding sources of methylmercury in songbirds with stable mercury isotopes: Challenges and future directions

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    Mercury (Hg) stable isotope analysis is an emerging technique that has contributed to a better understanding of many aspects of the biogeochemical cycling of Hg in the environment. However, no study has yet evaluated its usefulness in elucidating the sources of methylmercury (MeHg) in songbird species, a common organism for biomonitoring of Hg in forested ecosystems. In the present pilot study, we examined stable mercury isotope ratios in blood of 4 species of songbirds and the invertebrates they are likely foraging on in multiple habitats in a small watershed of mixed forest and wetlands in Acadia National Park in Maine (USA). We found distinct isotopic signatures of MeHg in invertebrates (both massâ dependent fractionation [as δ202Hg] and massâ independent fractionation [as Î 199Hg]) among 3 interconnected aquatic habitats. It appears that the Hg isotopic compositions in bird blood cannot be fully accounted for by the isotopic compositions of MeHg in lower trophic levels in each of the habitats examined. Furthermore, the bird blood isotope results cannot be simply explained by an isotopic offset as a result of metabolic fractionation of δ202Hg (e.g., internal demethylation). Our results suggest that many of the birds sampled obtain MeHg from sources outside the habitat they were captured in. Our findings also indicate that massâ independent fractionation is a more reliable and conservative tracer than massâ dependent fractionation for identifying sources of MeHg in bird blood. The results demonstrate the feasibility of Hg isotope studies of songbirds but suggest that larger numbers of samples and an expanded geographic area of study may be required for conclusive interpretation. Environ Toxicol Chem 2018;37:166â 174. © 2017 SETACPeer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/141144/1/etc3941.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/141144/2/etc3941_am.pd
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