Diversity and genealogy estimates.

<p>The diversity in disease and non-disease genes measured as the A) average intron SNP density, B) the average intron SNP density divided by intron divergence, C) and the mean minor allele frequency (MAF). Error bars represent the 95% confidence intervals.</p

Standardised regression coefficients from multiple regressions.

<p>Note that the replication time data is such that a negative slope indicates an increase in the variable through the cell cycle * p<0.05, ** p<0.01 and *** p<0.001.</p

CDS length.

<p>(A) Mean total CDS length, and (B) Mean average CDS length. Total CDS length is the sum of all constitutive and alternately spliced exons; average CDS length is the average CDS length of each transcript. Error bars represent the 95% confidence intervals.</p

Wellcome Trust data - Dryad

The Wellcome Trust data. Data given are the journal of publication, the score of the first and second assessors, the 2-year and 5-year impact factors and the number of citations as obtained from Google Scholar in 2011. Please cite Allen et al. (2009) PLoS One 4: e5910 and Eyre-Walker and Stoletzki (2013). PLoS Biolog

The distribution of the number of citations in journals with IF<5 and IF>30 in the F1000 dataset.

<p>The distribution of the number of citations in journals with IF<5 and IF>30 in the F1000 dataset.</p

Estimates of the selection index for individual genes under different evolutionary scenarios, assuming that all measurements are without error and can be obtained from an infinite number of individuals.

<p>A. Genes with true SI = −2 (negative selection) in red, genes with true SI = 0 (neutral evolution) in green and genes with true SI = 2 (positive selection) in blue. B. Genes with true SI = −5 in red, true SI = 0 in green and true SI = 5 in blue.</p

The proportion of papers, with between 90 and 110 citations in the F1000 dataset, scored in each category as a function of the IF of the journal in which the paper was published.

<p>The numbers of papers in each category are 131, 194, and 128 for IF<10, 1020, respectively.</p

The correspondence between assessor scores for the WT dataset.

<p>Table gives the number of papers rated 1 to 4 for the WT data. Figures in parentheses are the numbers expected by chance alone. Note the ordering of assessors is of no consequence in the WT data since the assessments were performed simultaneously and independently.</p

The correspondence between assessor scores for the F1000 dataset.

<p>Table gives the number of papers rated recommended, must read, or exceptional for F1000 papers when both assessments were made within 12 months. Figures in parentheses are the numbers expected by chance alone. Note the second assessor scored the paper after the first assessor and may have known the score the first assessor gave.</p

Tree illustrating the time between the most recent common ancestors of each species (<i>t_b</i>), the expected time to coalescence for two randomly chosen lineages within a given species (<i>t_w</i>) and the difference between <i>t_w</i> and the time at which all lineages coalesce (<i>t_c</i>).

<p>Tree illustrating the time between the most recent common ancestors of each species (<i>t_b</i>), the expected time to coalescence for two randomly chosen lineages within a given species (<i>t_w</i>) and the difference between <i>t_w</i> and the time at which all lineages coalesce (<i>t_c</i>).</p