Pathogenesis and pathology of hematogenous infections of the fetus and newborn

Made available in DSpace on 2011-11-01T16:37:06Z (GMT). No. of bitstreams: 2 license.txt: 1648 bytes, checksum: e095249ac7cacefbfe39684dfe45e706 (MD5) 2002 - pathogenesis and pathology of hematogenous infections2.pdf: 7096422 bytes, checksum: 632c0fc7f17d1151e45c67b9e268948e (MD5) Previous issue date: 2002Universidade da Bahia. Departamento de Patologia. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Laboratorio de Patologia. Rio de Janeiro, RJ, Brasil.The earlier infections occur in intrauterine life the more severe are they. When the infection develops during embryogenesis, the lesions are much more serious, sometimes causing disruptions (malformations). At this time the organs are not completely formed and microorganisms may interfere with organogenesis to such an extent that the development of the functions necessary for viability become impaired. Infection acquired in utero may result in resorption of the embryo, abortion, stillbirth, neonatal death, intrauterine growth retardation (IUGR), or prematurity. The infected newborns commonly are apparently normal at birth but they may develop a late onset disease. Otherwise, neonates presenting symptomatology may derelop untoward sequelae

Rhabdomyosarcoma mimicking Wilms' tumor

A case of a 6 year old child, with a pleomorphic rhabdomyosarcoma involving simultaneously the leg muscles and the kidney is reported. The renal tumor distorted the pyelocalycial system and Wilms' tumor was the clinical diagnosis. The authors discuss on the possible primary site of the tumor

The Placenta in hematogenous infections

Made available in DSpace on 2011-11-01T16:37:02Z (GMT). No. of bitstreams: 2 license.txt: 1648 bytes, checksum: e095249ac7cacefbfe39684dfe45e706 (MD5) 2002 - The Placenta in hematogenous infections.pdf: 2026852 bytes, checksum: 747add84a498b00204e41573ff354d1b (MD5) Previous issue date: 2002Universidade da Bahia. Departamento de Patologia. Salvador, BA, Brasil.Fundação Oswaldo Cruz. Instituto Fernandes Figueira. Laboratório de Patologia. Rio de Janeiro, RJ, Brasil.Although congenital infections have been known since ancient times, at present they constitute an evolution due to the broadening of diagnostic methods. Also, the histopathological examination of selected placentas has increased in perinatal pathology. All placentas should be examined grossly by the obstetrician or the neonatologist who must select the specimens to be sent for pathologic examination. The indications for selection at delivery to detect hematogenous infection are listed in Table 1. The placentas that do not meet guidelines for pathologic examination must be kept stored at 40 degrees C for at least 72 h. This routine ensures that the placentas of asymptomatic newborns who might present early manifestations suggestive of infection would be submittedfor pathologic examination