Investigating the Evidence of Behavioral, Cognitive, and Psychiatric Endophenotypes in Autism: A Systematic Review

Substantial evidence indicates that parents of autistic individuals often display milder forms of autistic traits referred to as the broader autism phenotype (BAP). To determine if discrete endophenotypes of autism can be identified, we reviewed the literature to assess the evidence of behavioral, cognitive, and psychiatric profiles of the BAP. A systematic review was conducted using EMBASE, MEDLINE, PsycINFO, PsycEXTRA, and Global Health. Sixty papers met our inclusion criteria and results are discussed according to the proportion of studies that yield significant deficits per domain. The behavioral, cognitive, and psychiatric endophenotypes in parents of autistic probands are still not clarified; however, evidence suggests mild social/communication deficits, rigid/aloof personality traits, and pragmatic language difficulties as the most useful sociobehavioral candidate endophenotype traits. The existence of deficits in the cognitive domain does suggest familial vulnerability for autism. Furthermore, increased depressed mood and anxiety can also be useful markers; however, findings should be interpreted with caution because of the small number of studies in such heterogeneously broad domains and several methodological limitations

Management of Scabies in Children Orphanage

Scabies is a skin condition caused by mites. This show symptoms such as intense itching at night in the crevices of the fingers, back and genitals. internal and external data in the form of a boy aged 6 years, living in orphanages, light activity, less personal and environmental hygiene, curative treatment patterns, density residence. Complaints of itching, especially at night repeatedly since about three months and experienced by some occupants orphanagesplace where patients live, not been treated previously.Having obtained a holistic intervention clinical decline and increased personal and environmental hygiene. The handling of family medicine effective in treatment of scabies. Where not only clinically but also solve the problem of tackling the risk of internal, external, and the environment

Development of 2.14 M one sheet canoe (SAMPAN) for pond activities

A 2.14 M length overall (LOA) flat bottom modern canoe (Sampan), was designed and constructed using locally available materials. The canoe features include easy construction, portability, least cost, light weight, shallow draft, and easy maneuverability. The light displacement (weight empty) was 25kg, which was less than local canoe of same size. When placed on water a draft of 5.5cm. The capacity of the canoe was 200kg, and the total production cost of N10, 000.00, ($67) which was not beyond the reach of an average fisher folks, or any fish farmer. The canoe was easily maneuvered when propelled by paddling as it floated at a shallow draft; this makes the canoe adequate for use on shallow water bodies such as ponds and reservoirs. The craft, because of its easy maneuverability, can also be used on shallow water bodies for recreational activities such as, sport fishing and canoeing

Pelaksanaan Bimbingan Karir Bagi Siswa SMA sebagai Persiapan Awal Memasuki Dunia Kerja

Bimbingan karir merupakan salah satu bentuk bimbingan yang terpadu pelaksanaannya dalam layanan bimbingan konseling di sekolah. Bimbingan karir merupakan salah satu bidang layanan bimbingan yang setara dengan tiga layanan bimbingan lainnya yaitu bimbingan belajar, bimbingan sosial, dan bimbingan pribadi. Program bimbingan karir di sekolah bertujuan untuk membantu anak dalam merencanakan karir di masa mendatang, agar karir yang dipilih sesuai dengan bakat minat dan nilai-nilai yang dijunjung tinggi. Jika orang memperoleh karir yang tepat maka hidup orang akhirnya akan bahagia. Dan kebahagiaan adalah tujuan hidup semua orang. Oleh sebab itu, bimbingan karir sejak usia dini merupakan bagian yang tak terpisahkan dari tugas pendidikan. Bimbingan karir tidak hanya sekedar memberikan respon kepada masalah-masalah yang muncul, akan tetapi juga membantu memperoleh pengetahuan, sikap, dan keterampilan yang diperlukan dalam pekerjaan

Analysis of activity concentrations due to natural radionuclides in the fish of Kainji Lake

A study was conducted for natural radioactivity of some fish samples from Kainji Lake, situated between latitudes 9~' 50' - 10~' 57' North and longitudes 4~'25'-4~'45' East, New Bussa, Niger state, Nigeria, using gamma spectroscopy method with Nal(TI) detector. Radioactivity a phenomenon that leads to production of radiations, and radiation is known to trigger or induce cancer. The fish are analyzed to estimate the radioactivity (activity) concentrations due to natural radionuclides (Radium 222(226Ra), Thorium 232(232Th) and Potassium 40 (40K). The obtained result shows that the activity concentration for (226Ra), in all the fish samples collected ranges from 16.06 ~c 0.44 Bqkg-1 to 67.39 ~c 12.34 Bqkg-1 with an average value of 37.22 ~c 4.31 Bqkg-1. That of 232Th, ranges from 42.66 ~c 0.81 Bqkg-1 to 200.6 ~c 10.66 Bqkg-1 and the average value stands at 94.82 ~c 3.82 Bqkg-1. The activity concentration for 40K, ranges between 243.3 ~c 1.56 Bqkg-1 to 384.98 ~c 11.97 Bqkg-1 and the average is 618.2 ~c 26.81 Bqkg-1. This indicated that average daily intake due to natural activity from the fish is valued at 0.999 Bq/day, 2.545Bq/day and 10.31 Bq/day for 226Ra, 232Th and 40K respectively. This shows a promising result, since the activity concentration values for most of the fish are within the acceptable limits. However location Upstream02 (9~'51'.285~AN, 4~'35'.533~AE) and Upstream07 (9~'51'.285~AN, 4~'35'.533~AE) fish, became outliers with significant values of 1 13.10~kSvy-1 and 121.68~kSvy-1 effective dose. This could be attributed to variation in geological formations in the lake as well as the feeding habits of these fish. The work shows that consumers of fish from Kainji Lake have no risk of radioactivity ingestion, even though no amount of radiation is assumed to be totally safe

Design and construction of a simple boat trailer for Federal College of Freshwater Fisheries Technology, New Bussa

A simple boat trailer with an overall length of 4.59m, breathes 1.68m, and weight of 87kg was designed and constructed using locally available metals and scrap materials. The boat trailer was used to tow a boat of 250kg weight through a distance of 14km without affecting the safety and speed of the car. The construction resulted to the production of an open cart that is light and easily maneuvered that one person can move it manually without difficulty. The total production cost was N32, 300 which is affordable in relation to the cost of transporting boats through the use of pick up vans. The boat trailer can be easily maneuvered when coupled to any car or van. This makes it adequate for towing and for safer movement of boats from the school boat yard to any water bodies

ANALGESIC EFFECT AND ANTI-INFLAMMATORY ACTIVITY OF AQUEOUS EXTRACT OF BOSWELLIA DALZIELII (BURSERACEAE) STEM BARK

Objective: To evaluate the analgesic effect and anti-inflammatory properties of Boswellia dalzielii (Burseraceae), a medicinal plant commonly used in northern Nigeria as an anti-diarrhoeal, antipyretic, analgesic and anti-inflammatory agent.Methods: Three doses (25 mg/kg, 50 mg/kg and 100 mg/kg) of the crude aqueous extract of Boswellia dalzielii were evaluated for analgesic and anti-inflammatory activities using the acetic acid-induced writhing test, formalin-induced nociception and formalin-induced hind paw oedema in rats. The acute oral toxicity was carried out using the up and down procedure as described by the OECD guidelines.Results: All doses (25, 50 and 100 mg/kg) of the extract tested were effective against acetic acid induced abdominal constrictions producing a percentage inhibition of (55.43, 69.56 and 71.73%) respectively. A percentage inhibition of the formalin-induced nociception of (7.31, 31.70 and 48.78%-early phase) and (12.82, 21.79 and 48.71%-late phase) respectively was also produced. For the acetic acid writhing test, the percentage inhibition obtained at the dose of 50 and 100 mg/kg (69.56 and 71.73%) were higher than that of the standard drug (Piroxicam, 10 mg/kg) (59.78%). For formalin-induced nociception, the test extract at 100 mg/kg showed a higher percentage inhibition compared to Piroxicam, in early (48.78 and 43.90%) and late phase (48.71 and 39.74 %) respectively. The extract, however, did not show a significant activity against formalin-induced paw oedema at all the doses used.Conclusion: The present study demonstrated that Boswellia dalzielii has significant analgesic properties comparable to that of the standard drug (10% Piroxicam), thus validating the traditional claim of its antinociceptive property

Implementasi Fullday School Dalam Meningkatkan Hasil Belajar Siswa

Tujuan penelitian adalah untuk mendeskripsikan implementasi fullday school dalam meningkatkan hasil belajar siswa. Jenis penilitian yang digunakan adalah penelitian kualitatif. dimana akan memberikan gambaran secara kualitatif berdasarkan data dan informasi aktual. Subjek dalam penelitian ini adalah kepala sekolah, guru, dan siswa. Teknik pengumpulan data dilakukan dengan obsevasi, wawancara, dan dokumentasi. Analisis data menggunakan teknik reduksi data, penyajian data, dan penarikan kesimpulan. Untuk menguji keabsahan data menggunakan uji kredibilitas dengan pendekatan trianggulasi yaitu trianggulasi sumber, trianggulasi teknik, dan trianggulasi waktu. Hasil penelitian yaitu a) lingkungan belajar, dilakukan dengan menyediakan sarana prasarana belajar yang memadai, selain ruangan kelas, di sekolah ini juga terdapat ruangan-ruangan belajar tempat praktek lapangan, b) strategi belajar dengan menciptakan suasana pembelajaran 3M (menyenangkan, mengasyikkan dan mencerdaskan,  c) metode belajar, digunakan sesuai kondisi ruangan belajar dan materi belajar yang akan disajikan, metode belajar yang sering digunakan yaitu, ceramah, tanya jawab, diskusi dan demonstrasi, d) tersedianya komputer, dan perlengkapan peralatan listrik yang yang berbasis teknologi. &nbsp

Formation of magnetic minerals at hydrocarbon-generation conditions

In this paper, we report the pyrolysis and formation of magnetic minerals in three source rock samples from the Wessex Basin in Dorset, southern England. The experimental conditions in the laboratory recreated the catagenesis environment of oil source rocks. Magnetic analysis of both the heated and the unheated samples at room temperature and at very low-temperatures (5 K), coupled with transmission electron-microscopy imaging and X-ray analysis, revealed the formation of nanometre-sized (<10 nm), magnetic particles that varied across the rock samples analysed, but more importantly across the pyrolysis temperature range. Magnetic measurements demonstrated the formation of these magnetic minerals peaked at 250 °C for all rock samples and then decreased at 300 °C before rising again at 320 °C. The newly formed magnetic minerals are suggested to be primarily pyrrhotite, though magnetite and greigite are also thought to be present. The sizes of the magnetic minerals formed suggest a propensity to migrate together with oil potentially explaining the magnetic anomalies observed above and within oil fields

Design and construction of 2.14 m. LOA (one sheet) flat bottom canoe (punt) for pond activities

A 2.14M length overall (LOA) flat bottom canoe (punt), was designed and constructed using locally available materials. The features of the canoe are least cost material, light weight, shallow draft and easy maneuverability. The canoe's light displacement (weight empty) was 28kg, which was less.than local canoe of same size. When placed on water a draft of 5.5cm was achieved which is 14.8% of its depth (37cm). The capacity of the canoe was 200kg, and the total production cost of N8, 700.00 which was, not beyond, the reach of an average fisher folks, or any fish farmer. The canoe was easily maneuvered when propelled by paddling as it floated at a shallow draft; this makes the canoe adequate for use on shallow water bodies such as ponds and reservoirs. Such easily maneuvered craft can also be used on pond or reservoirs for recreation which include, sport fishing, canoein