Fokus 2015: Die Millenniums-Entwicklungsziele – Magna Charta der Globalisierung? Eine Zwischenbilanz – 5 Jahre nach der UN-Millenniumserklärung. Dokumentation der gleichnamigen Konferenz am 25. Januar 2005 in Berlin

The purpose of this paper is to explore how sustainable competitive advantage is generated in two Swedish best practice companies that successfully exploit logistics as a source for competitive advantage. Using a theoretical framework based on the resource-based view of the firm, this research elaborates on the links between operational and dynamic logistics capabilities and sustainable competitive advantage. The findings conclude that a sustainable competitive advantage is based on a combination of efficient and effective logistics operations and well-functioning, adjusted, in-house-developed IT systems. This operational capability is in turn sustained through five dynamic capabilities: managerial knowledge and presence, cross-functional teamwork, control, learning and supply chain relationships.  This is an electronic version of an article published in:Erik Sandberg and Mats Abrahamsson, Logistics capabilities for sustainable competitive advantage, 2011, International Journal of Logistics, (14), 1, 61-75.International Journal of Logistics is available online at informaworldTM: http://dx.doi.org/10.1080/13675567.2010.551110Copyright: Taylor & Francishttp://www.tandf.co.uk/journals/default.as

Vattenapeteorin: Paradigmskifte eller pseudovetenskap?

The Aquatic Ape theory was first formulated by Alister Hardy in year 1960. All from the beginning the theory has been criticized, ridiculed, ignored and a source to strong feelings in the anthropological community. The purpose of this essay is to investigate why the Aquatic Ape theory is so controversial and why it is understood so differently by scientists. After interviews with Swedish scientists and the general community, and after reading of anthropological books, I have tried to show that the aquatic ape-coldness depends on it challenging nature against the anthropological paradigm, which describes human beings as strong, hunting creatures who can live in any environment. The Aquatic Ape theory - on the other hand - picks out one of all these environments and says: "here has our evolution occurred: we have been aquatic apes". Due to this, the theory has become an anomaly; it has been ignored, eliminated and stigmatized. Today, the Aquatic Ape is going through a dramatic change. Its proponents want to change its name to the Seashore Ape theory and they try to adapt the theory to the anthropological paradigm. For example they reduce the aquatic evolution phase to a short period from approximately 5 to 7 million years ago. This weaker version of the original theory is, though, more or less useless and it is quite easy to reject. Consequently: the aquatic ape needs to be an anomaly, otherwise it can?t exist. I can see two possible future scenarios for the Aquatic Ape theory. The first scenario is that the old anthropological paradigm continues to be intact, and then is the aquatic ape doomed to remain anonymous. The other scenario is that someone formulates a completely new paradigm where human beings are seen as environmental specialist rather than environmental generalists. Only here is the aquatic ape going to find an acceptable and essential role in the explanation of human evolution

Opinion Dynamics with Random Actions and a Stubborn Agent

We study opinion dynamics in a social network with stubborn agents who influence their neighbors but who themselves always stick to their initial opinion. We consider first the well-known DeGroot model. While it is known in the literature that this model can lead to consensus even in the presence of a stubborn agent, we show that the same result holds under weaker assumptions than has been previously reported. We then consider a recent extension of the DeGroot model in which the opinion of each agent is a random Bernoulli distributed variable, and by leveraging on the first result we establish that this model also leads to consensus, in the sense of convergence in probability, in the presence of a stubborn agent. Moreover, all agents' opinions converge to that of the stubborn agent.Comment: 5 pages; This work was presented at Asilomar Conference on Signals, Systems, and Computers 201

Gemtuzumab ozogamicin as postconsolidation therapy does not prevent relapse in children with AML: results from NOPHO-AML 2004.

To access publisher full text version of this article. Please click on the hyperlink in Additional Links field.There are no data on the role of postconsolidation therapy with gemtuzumab ozogamicin (GO; Mylotarg) in children with acute myeloid leukemia (AML). The NOPHO-AML 2004 protocol studied postconsolidation randomization to GO or no further therapy. GO was administered at 5 mg/m(2) and repeated after 3 weeks. We randomized 120 patients; 59 to receive GO. Survival was analyzed on an intention-to-treat basis. The median follow-up for patients who were alive was 4.2 years. Children who received GO showed modest elevation of transaminase and bilirubin without signs of veno-occlusive disease. Severe neutropenia followed 95% and febrile neutropenia 40% of the GO courses. Only a moderate decline in platelet count and a minor decrease in hemoglobin occurred. Relapse occurred in 24 and 25 of those randomized to GO or no further therapy. The median time to relapse was 16 months versus 10 months (nonsignificant). The 5-year event-free survival and overall survival was 55% versus 51% and 74% versus 80% in those randomized to receive GO or no further therapy, respectively. Results were similar in all subgroups. In conclusion, GO therapy postconsolidation as given in this trial was well tolerated, showed a nonsignificant delay in time to relapse, but did not change the rate of relapse or survival (clinicaltrials.gov identifier NCT00476541).Swedish Childhood Cancer Foundation Danish Childhood Cancer Foundation Karen Elise Jensen Foundation Wyet

BioVEC: A program for Biomolecule Visualization with Ellipsoidal Coarse-graining

Biomolecule Visualization with Ellipsoidal Coarse-graining (BioVEC) is a tool for visualizing molecular dynamics simulation data while allowing coarse-grained residues to be rendered as ellipsoids. BioVEC reads in configuration files, which may be output from molecular dynamics simulations that include orientation output in either quaternion or ANISOU format, and can render frames of the trajectory in several common image formats for subsequent concatenation into a movie file. The BioVEC program is written in C++, uses the OpenGL API for rendering, and is open source. It is lightweight, allows for user-defined settings for and texture, and runs on either Windows or Linux platforms

Programmable models of growth and mutation of cancer-cell populations

In this paper we propose a systematic approach to construct mathematical models describing populations of cancer-cells at different stages of disease development. The methodology we propose is based on stochastic Concurrent Constraint Programming, a flexible stochastic modelling language. The methodology is tested on (and partially motivated by) the study of prostate cancer. In particular, we prove how our method is suitable to systematically reconstruct different mathematical models of prostate cancer growth - together with interactions with different kinds of hormone therapy - at different levels of refinement.Comment: In Proceedings CompMod 2011, arXiv:1109.104

Generalization of a Real-Analysis Result to a Class of Topological Vector Spaces

In this paper, we generalize an elementary real-analysis result to a class of topological vector spaces. We also give an example of a topological vector space to which the result cannot be generalized.Comment: 6 pages, no figure