第840回千葉医学会整形外科例会 25.

Phylogenetic tree of 47 species. (PDF 15 kb

Heterogeneity of different genome fractions (·10⁻²).

<p>The deviation of the sampled median values is less than 0.0001 in all genomes for each of the three scores.</p><p>*H_c, H_o and H_t – compositional, organizational and total heterogeneity scores. Note that H_c is calculated as median of differences in GC content while H_t and H_o scores are evaluated based on comparison of compositional spectra (see section <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0032076#s2" target="_blank">Methods</a>);</p><p>**only large chromosomes 1–8 were taken into account.</p

Predicted and observed values of human intra- and inter-chromosomal heterogeneity estimates.

<p>Axes X: predicted values, axes Y: observed values. (A) intra-chromosomal H_t; (B) average inter-chromosomal H_t; (C) intra-chromosomal H_o; (D) average inter-chromosomal H_o.</p

List of genomes used for analyses.

<p>*incomplete genome sequences.</p

The distribution histogram of human median inter-chromosomal CS-distances obtained with different permitted maximal levels of GC differences between scored 100 kb segments.

<p>The inter-chromosomal CS-distances obtained without restriction on inter-segmental GC differences contain both compositional and organizational components of inter-chromosomal heterogeneity (thereby coinciding with H_t). The stricter conditions on ΔGC reduce the influence of H_c on the estimate of H_o. All ΔGC thresholds that are ≤0.02 show just slightly different distributions of human inter-chromosomal H_o. Therefore, we believe that ΔGC≤0.02 condition permits us to assess organizational inter-chromosomal heterogeneity without the influence of compositional heterogeneity.</p

The most significant predictors of intra- and inter-chromosomal heterogeneity scores H_t and H_o.

<p>The most significant predictors of intra- and inter-chromosomal heterogeneity scores H_t and H_o.</p

Intragenome heterogeneity and relationships between total and organizational (A), organizational and compositional (B) heterogeneity types, and organizational heterogeneity and genome GC content (C).

<p>Every series corresponds to one species group: ⧫ apes; ▴ other primates; ▪ Rodents; ▴ Ungulates; • other mammals; ⧫ Marsupials; • Birds; ⧫ Fishes; ▴ other vertebrates. The species surrounded by a dashed ellipse appeared to be outliers due to their organizational heterogeneity (see explanation in the text).</p

Whole-genome and inter-chromosomal heterogeneity scores H_t, H_o, and H_c for different groups of analyzed vertebrate genomes: (A) total heterogeneity, (B) organizational heterogeneity, (C) compositional heterogeneity; Legends: P. primates, U. ungulates, R. rodents, B. birds, F. fishes, O. other vertebrates; black bars correspond to standard error.

<p>Whole-genome and inter-chromosomal heterogeneity scores H_t, H_o, and H_c for different groups of analyzed vertebrate genomes: (A) total heterogeneity, (B) organizational heterogeneity, (C) compositional heterogeneity; Legends: P. primates, U. ungulates, R. rodents, B. birds, F. fishes, O. other vertebrates; black bars correspond to standard error.</p

Organizational heterogeneity of natural sequences of different genome fractions and corresponding reshuffled sequences with varied GC content: (A) natural sequences, (B) reshuffled sequences.

<p>Organizational heterogeneity of natural sequences of different genome fractions and corresponding reshuffled sequences with varied GC content: (A) natural sequences, (B) reshuffled sequences.</p

Application of music therapy techniques in cognitive rehabilitation

Table listing the genotype fixed in both control group and desiccation group. (XLSX 2892 kb