Inflammatory Myofibroblastic Tumor Report of a Rare Case in Kidney

Inflammatory myofibroblastic tumor (IMT) is a rare neoplasm mostly seen in the lungs, but also in extrapulmonary sites. The most common genitourinary site of IMT is the bladder, but it may rarely be seen in the kidneys. We report a case of a 15-year-old girl presented with flank pain and hematuria, in which computed tomography scan revealed a mass in the left kidney. The patient underwent left nephrectomy for a diagnosis of Wilms tumor. Further assessment of the tissue demonstrated a pathologic diagnosis of IMT. Despite improvements in imaging technology, the preoperative diagnosis of IMT remains difficult and surgery is the only way for the diagnosis and treatment. Considering the role of the pathologic examination in making the definite diagnosis of IMT, we should be aware of this entity and it must be considered in the differential diagnoses

Comparison of Growth Parameters of Infants of Ramadan Fasted and Non-Fasted Mothers

Introduction: The many advantages of exclusively breast feeding infants are documented; breast-feeding enhances the growth and development of breast fed infants. The impact of Ramadan fasting by breast-feeding mothers on the growth parameters of exclusively breast-fed infants is still not clear. The aim of this study was to evaluate the impact of maternal fasting during Ramadan on the growth parameters of their exclusively breast-fed infants. Material and methods: This cohort study was performed throughout Ramadan and for five months after, on healthy, exclusive breast-fed infants (n=116), aged between 15 days to 6 months, assigned into two groups, based on their mothers fasting: Control group (n=80) and fasting group (infants with fasting mothers: n=36). All infants underwent periodic physical examinations twice in Ramadan, 3 times in the second month and then twice monthly in next 4 months. The infant’s growth status was evaluated by calculating each growth parameters (weight, height, head circumference) as a percentage of the median value for age, based on appropriate growth charts. Results: The mean age of infants in the case group was 3.43 ± 1.38 and in the control group was 2.31±1.45 months, age being significantly different between the two groups (P<0.05). Fifty-four (46.6%) were boys and this proportion was the same in both groups (P>0.05). According to the repeated measures ANOVA, all growth parameters increased during the study period (P< 0.05) but the rate of increaseing was the same for both groups (P>0.05). Conclusion: Ramadan fasting by breastfeeding mothers did not adversely affect on the growth parameters of exclusively breast-fed infants

Increased Levels of IL-10, IL-12, and IFN-gamma in Patients with Visceral Leishmaniasis

Visceral leishmaniasis remains a serious public health problem in developing countries. Cytokines have a crucial role in the pathogenesis of this disease. We evaluated plasma levels of IL-10, IL-12 and IFN-gamma in 32 patients with active visceral lieshmaniasis, in 29 siblings of the patients and in 23 normal individuals in an endemic area to look for correlations between the clinical outcome of infection and the plasma cytokine levels. An analysis was made with a skin test and a quantitative sandwich enzyme immunoassay. Data were analyzed with the Mann Whitney test and the Kruskal Wallis test. The cytokine levels were significantly higher in the patients than in the control groups. We concluded that normalization of the plasma level of IFN-gamma can serve as a reliable parameter for considering the patient as cured

Increased levels of IL-10, IL-12, and IFN-in patients with visceral leishmaniasis

Visceral leishmaniasis remains a serious public health problem in developing countries. Cytokines have a crucial role in the pathogenesis of this disease. We evaluated plasma levels of IL-10, IL-12 and IFN-γ in 32 patients with active visceral lieshmaniasis, in 29 siblings of the patients and in 23 normal individuals in an endemic area to look for correlations between the clinical outcome of infection and the plasma cytokine levels. An analysis was made with a skin test and a quantitative sandwich enzyme immunoassay. Data were analyzed with the Mann Whitney test and the Kruskal Wallis test. The cytokine levels were significantly higher in the patients than in the control groups. We concluded that normalization of the plasma level of IFN-γ can serve as a reliable parameter for considering the patient as cured

Incidence and bacteriological profile of neonatal conjunctivitis in Hajar Hospital, Shahrekord, Iran

Background and Objective: In Iran, prenatal Chlamydia and gonorrhea screening of pregnant women and neonatal eye prophylaxis are not routine practice. The present research aimed to identify bacterial agents of neonatal conjunctivitis. Materials & Methods: A cross sectional study was conducted on all babies born over a period from April 2007 to April 2008 in Hajar Hospital of Shahrekord University of Medical Sciences. Babies presenting clinical signs of erythema and edema of eyelid and purulent eye discharge were considered as clinical conjunctivitis. Specimens were obtained in all cases with conjunctivitis and were performed gram staining and cultures in specific media. A simple ELISA has been performed for measurement the immunoglobin M antibody to C. trachomatis and positive result rechecked by indirect immunoflurescent test. Results: During the period of one year, 223 neonates have revealed bacterial conjunctivitis. The incidence rate of neonatal conjunctivitis was 2.8. Chlamydia conjunctivitis was identified in 13.6 of cases and gonococcal conjunctivitis was identified in 5.5 of cases. Discussion: The high incidence rate of Chlamydia and gonococcal conjunctivitis, have revealed that the eye prophylaxis from ophthalmia neonatorum is needed promptly

Impact of maternal Ramadan fasting on growth parameters in exclusively breast-fed infants

Introduction: There are many advantages of breast milk for infants. The impact of Ramadan fasting of breast-feeding mothers on their exclusively breast-fed infants’ growth is still not clear. The objective of this study is to determine the impact of maternal Ramadan fasting on growth parameters of exclusively breast-fed infants. Methods: This cohort study was conducted during Ramadan and five months after Ramadan on 116 healthy, exclusively breast-fed infants aged 15 days to 6 months. 36 infants, whose mothers fasted throughout Ramadan (case group) and 80 infants, whose mothers did not fast (control group), were enrolled in the study. All infants underwent periodic physical examinations, twice in Ramadan, 3 times in the second month and twice monthly in the next 4 months. The data analyses were done using a repeated measure analysis of variance. Statistical significance was defined as P<0.05. Analyses were performed using SPSS statistical package and repeated measures ANOVA. Findings: All growth parameters increased during the study period (P< 0.05), rate of increase being the same for both groups (P>0.05). There is obvious increasing trend for all growth parameters; this trend depends on age and is almost similar for both groups. Conclusion: Ramadan fasting by breast-feeding mothers did not adversely affect the growth parameters of exclusively breast-fed infants in short-term

First seroprevalence survey of children with tularemia infection in Chaharmahal va Bakhtiari Province, Iran

Background and Objectives: An increasing number of tularemia was reported in all over the world. This infection is characterized by different clinical syndromes that can be considered in differential diagnosis of infectious disease. Despite effective antibiotics against Francisella tularensis, this infection is still as one of the agent of mortality and disability among infectious disease. The aim of this study was investigation of seroepidemiological of F. tuleransis among children between 2-18 years old in a risky zone in Iran. Methods: This cross-sectional, laboratory-based study in two distinct villages Saragha seyed and Khoye in Chaharmahal va bakhtiari Province involved 183 children, adolescents who had no sign and symptom of disease and were screened for tularemia immunoglobulins G (IgG), using the ELISA-based quantitative assay. Results: In general, from 183 children 11 persons (6) were seropositive, compared with 172 persons (94) were seronegative. Conclusion: According to the high prevalence of antibodies against F. tularensis in this study, this infection must be considered as differential diagnosis of infectious disease in suspect patients

The Effect of Magnesium Sulfate on Renal Colic Pain Relief; a Randomized Clinical Trial

Introduction: Renal colic can be managed by preventing the contraction movements of ureter muscles. By reducing acetylcholine in the nerve terminals, magnesium sulfate could be effective in this regard. The aim of this study is to investigate the effect of magnesium sulfate on acute renal colic pain relief. Method: The present study was a double-blind clinical trial in which the patients suffering from acute renal colic were randomly divided into 2 groups of who either received standard protocol (intravenous infusion of 0.1 mg/Kg morphine sulfate, 30 mg of Ketorolac, and 100 ml normal saline as placebo/15 minutes) or standard protocol plus 15 mg/Kg of intravenous magnesium sulfate 50%/100 ml normal saline/15 minutes. Severity of patients’ pain was measured by visual analogue scale (VAS) at baseline, and 30 and 60 minutes after infusion. The collected data were analyzed using STATA statistical software. Results: 100 cases were randomly allocated to intervention or control group. The two groups were similar in baseline pain score and demographic characteristics. At 30 and 60 minutes, mean pain score was less in the intervention group compared to the control group. Moreover, the difference between the two groups was statistically significant regarding the additional amount of morphine, suggesting that the intervention group needed less additional morphine than the control group. Conclusion: The results of this study showed that Magnesium sulfate can be used as an adjunct drug in treatment of patients suffering from renal colic. It not only alleviates the pain in the patients, but also diminishes the need for pain medications