28 research outputs found
A Generalization of Notion Group as Dynamical Groups
In this paper the concept of groups will be extended by a dynamical system to the dynamical groups and we will investigate some results about them. Also notions coset and qoutient dynamical group are introduced
In vivo effects of allogeneic mesenchymal stem cells in a rat model of acute ischemic kidney injury
Objective(s): Renal ischemia-reperfusion injury (IRI) as a severe condition of acute kidney injury (AKI) is the most common clinical problem with high mortality rates of 35-60% deaths in hospital. Mesenchymal stem cells (MSC) due to unique regenerative characteristics are ideal candidates for the treatment of the ischemic injuries. This work is focused on the administration of MSC to IRI-induced AKI Wistar rats and evaluating their significance in AKI treatment. Material and Methods: Animals underwent surgical procedure and AKI was induced by 40 min bilateral renal pedicle clamping. Immediately after reperfusion, 2Ă106 rat bone marrow derived MSCs were injected via intra-parenchymal or intra-aortic route. Results: Animals subjected to AKI after days 1 and 3 showed significant increase in the serum creatinine and blood urea nitrogen (BUN) concentration along with a declined glomerular filtration rate (GFR) when compared with non-ischemic animals. On the other hand, treated animals showed a significant enhanced regeneration as compared to ischemic animals in both administration route groups. Conclusion: According to the results concluded from the renoprotective effects of MSC in IRI/AKI, MSCs could be considered as promising therapeutic approach for AKI in clinical applications
Doxorubicin-induced renal inflammation in rats: Protective role of Plantago major
Objective: The aim of the present study was to evaluate the possible protective effect of Plantago major (P. major) extract against doxorubicin (DXR)-induced renal inflammation in rats. Materials and Methods: 80 male albino rats were randomly divided into 8 groups as follows: control, DXR, Ext (extract) 600, Ext1200, dexamethasone+DXR, vitamin E+DXR, Ext600+DXR, and Ext1200+DXR. Duration of the study was 35 days and DXR was intravenously injected on the 7th day of the experiment. Tumor necrosis factor-alpha (TNF-α) production and monocyte chemoattractant protein-1 (MCP-1) expression levels were assessed in the left kidney. Serum creatinine concentration and osmolarity were determined on the 1st, 14th, 21st, 28th and 35th days of the experiment. Results: DXR caused a significant increase in renal expression of MCP-1 and TNF-α production compared to control animals. Administration of dexamethasone, vitamin E and P. major extract significantly improved the expression of these inflammatory mediators compared to DXR group. Compared to day 1 in DXR group, serum osmolarity showed a significant increase on days 21, 28 and 35. Also, on these days, serum osmolarity in DXR group was significantly higher than that on the same days in control group. In Vit E+DXR and Ext 1200+DXR groups, there was no significant changes in serum osmolarity among different days of the study. However, in these groups, serum osmolarity on days 21, 28 and 35 showed a significant decrease compared to the same days in DXR group. Conclusion: Present results suggest that hydroethanolic extract of P. major protected renal tissue against DXRâinduced renal inflammation
Logical entropy of quantum dynamical systems
This paper introduces the concepts of logical entropy and conditional logical entropy of hnite partitions on a quantum logic. Some of their ergodic properties are presented. Also logical entropy of a quantum dynamical system is dehned and ergodic properties of dynamical systems on a quantum logic are investigated. Finally, the version of Kolmogorov-Sinai theorem is proved
Logical Divergence, Logical Entropy, and Logical Mutual Information in Product MV-Algebras
In the paper we propose, using the logical entropy function, a new kind of entropy in product MV-algebras, namely the logical entropy and its conditional version. Fundamental characteristics of these quantities have been shown and subsequently, the results regarding the logical entropy have been used to define the logical mutual information of experiments in the studied case. In addition, we define the logical cross entropy and logical divergence for the examined situation and prove basic properties of the suggested quantities. To illustrate the results, we provide several numerical examples
R-Norm Entropy and R-Norm Divergence in Fuzzy Probability Spaces
In the presented article, we define the R-norm entropy and the conditional R-norm entropy of partitions of a given fuzzy probability space and study the properties of the suggested entropy measures. In addition, we introduce the concept of R-norm divergence of fuzzy P-measures and we derive fundamental properties of this quantity. Specifically, it is shown that the Shannon entropy and the conditional Shannon entropy of fuzzy partitions can be derived from the R-norm entropy and conditional R-norm entropy of fuzzy partitions, respectively, as the limiting cases for R going to 1; the KullbackâLeibler divergence of fuzzy P-measures may be inferred from the R-norm divergence of fuzzy P-measures as the limiting case for R going to 1. We also provide numerical examples that illustrate the results
Logical Entropy of Dynamical SystemsâA General Model
In the paper by RieÄan and MarkechovĂĄ (Fuzzy Sets Syst. 96, 1998), some fuzzy modifications of Shannonâs and Kolmogorov-Sinaiâs entropy were studied and the general scheme involving the presented models was introduced. Our aim in this contribution is to provide analogies of these results for the case of the logical entropy. We define the logical entropy and logical mutual information of finite partitions on the appropriate algebraic structure and prove basic properties of these measures. It is shown that, as a special case, we obtain the logical entropy of fuzzy partitions studied by MarkechovĂĄ and RieÄan (Entropy 18, 2016). Finally, using the suggested concept of entropy of partitions we define the logical entropy of a dynamical system and prove that it is the same for two dynamical systems that are isomorphic
Logical entropy of dynamical systems
Abstract The main purpose of the paper is to extend the results of Ellerman (Int. J. Semant. Comput. 7:121â145, 2013) to the case of dynamical systems. We define the logical entropy and conditional logical entropy of finite measurable partitions and derive the basic properties of these measures. Subsequently, the suggested concept of logical entropy of finite measurable partitions is used to define the logical entropy of a dynamical system. It is proved that two metrically isomorphic dynamical systems have the same logical entropy. Finally, we provide a logical version of the KolmogorovâSinai theorem on generators. So it is shown that by replacing the Shannon entropy function by the logical entropy function we obtain the results analogous to the case of classical KolmogorovâSinai entropy theory of dynamical systems
Role of the Nitrergic System of the Cuneiform Nucleus in Cardiovascular Responses in Urethane-Anesthetized Male Rats
Background: The presence of nitric oxide (NO) in the cuneiform nucleus (CnF) has been previously shown. In this study, NG-nitro-L-arginine methyl ester (L-NAME) (an inhibitor of NO synthase), L-arginine (L-Arg) (a precursor of NO), and sodium nitroprusside (SNP) (a donor of NO) were microinjected into the CnF and cardiovascular responses were investigated. Methods: Seventy male rats were divided into 7 groups (n=10 each): 1) saline, 2 and 3) L-NAME (30 and 90 nmol), 4 and 5) L-Arg (20 and 60 nmol), and 6 and 7) SNP (9 and 27 nmol). After anesthesia, the femoral artery was cannulated and cardiovascular parameters were recorded using a PowerLab system. Time course changes in mean arterial pressure (ÎMAP) and heart rate (ÎHR) were calculated and compared with those in the control group (repeated measures ANOVA). Maximum âMAP and âHR were also compared with those in the control group (independent sample t test).
Results: âMAP with both doses of L-NAME (30: P=0.026 and 90: P=0.007) and âHR with the higher dose (P=0.034) were significantly higher than those in the control group. Maximal âMAP with both doses (P<0.01 and P<0.001, n=10) and maximal âHR with the higher dose (P<0.01) were significantly higher than those in the control group. Changes in L-Arg with both doses were not significantly higher than those in the control group (P=0.26, n=8). âMAP and âHR of SNP only with the higher dose were significantly lower than those in the control group (P=0.006 and P=0.035), and maximal responses with the higher dose were lower than those in the control group (âMAP: P<0.01 and âHR: P<0.05, n=7).
Conclusion: Our results showed that the nitrergic system of the CnF had an inhibitory effect on central cardiovascular regulation