1,757 research outputs found
Validity of MTI (Actigraph) for physical activity measurement in children with cerebral palsy
Theme: Adapted Physical Activity Over Life-SpanINTRODUCTION: Physical activity (PA) measurement among children with cerebral palsy (CP) has not been adequately established. CP involves a wide range of disabilities, and the assessment of PA in this population is of importance to the design and implementation of health, therapy, and physical education programs (Kim, 2009; Pirpiris & Graham, 2004). The purpose of this study is to examine the validity of MTI (Actigraph) as a PA measurement instrument for children with CP. METHODS: Participants included 31 children with CP (17 female and 14 male) aged 6 to14 years (M = 9.71 years, SD = 2.52 years). The participants were classified within Gross Motor Classification System (GMFCS) I to III, and took part in two activity sessions: (1) structured activity protocol with increasing intensities and (2) free play session. MTI was used to measure activity counts, heart rate was measured …postprin
Clinically important differences in the intensity of chronic refractory breathlessness
Context: Clinically important differences in chronic refractory breathlessness are ill defined but important in clinical practice and trial design. Objectives: To estimate the clinical relevance of differences in breathlessness intensity using distribution and patient anchor methods. Methods: This was a retrospective data analysis from 213 datasets from four clinical trials for refractory breathlessness. Linear regression was used to explore the relationship between study effect size and change in breathlessness score (0-100 mm visual analogue scale) and to estimate the change in score equivalent to small, moderate, and large effect sizes. Pooled individual blinded patient preference data from three randomized controlled trials were analyzed. The difference between the mean change in Day 4 minus baseline scores between preferred and non-preferred arms was calculated. Results: There was a strong relationship between change in score and effect size (P = 0.001; R 2 = 0.98). Values for small, moderate, and large effects were -5.5, -11.3, and -18.2 mm. The participant preference change in score was -9 mm (95% CI, -15.8, -2.1) (P = 0.008). Conclusion: This larger dataset supports a clinically important difference of 10 mm. Studies should be powered to detect this difference
Mentoring: A Select Annotated Bibliography
Increasingly, librarians have been engaged in discussions of the disconnect between the content covered in LIS education and the skills required to successfully navigate the first several years of work as a library professional (Andersen, 2002; Westbrock & Fabien, 2010). Mentoring has proven to be an important avenue for newly-degreed professionals to transition into the professional environment and bridge the gap between education and practice (Hallam & Newton-Smith, 2006). While examining the existing literature, a clear divide emerges between discussions of mentoring programs and mentoring relationships. This annotated bibliography seeks to bridge this disconnect by examining literature using narrative analysis as the primary methodology, which provides material covering both the programmatic and relational aspects of mentoring in the Library and Information Science profession. Library leaders and new professionals alike can benefit from this focused review of the literature as it provides an overview of both benefits and drawbacks of mentoring programs and relationships while reducing the information overload found in exploring this significant area of library and information science research
Private irrigation in Sub-Saharan Africa: regional Seminar on Private Sector Participation and Irrigation Expansion in Sub-Saharan Africa, Accra, Ghana, 22-26 October 2001
Irrigation management / Privatization / Irrigated farming / Financing / Irrigation systems / Gender / Women / Government managed irrigation systems / Farmer managed irrigation systems / Rice / Horticulture / Technology transfer / Pumps / Drip irrigation / Filtration / Capacity building / Urban agriculture / Poverty / Water users associations / Agricultural credit
Brain regions concerned with perceptual skills in tennis: An fMRI study
Sporting performance makes special demands on perceptual skills, but the neural mechanisms underlying such performance are little understood. We address this issue, making use of fMRI to identify the brain areas activated in viewing and responding to video sequences of tennis players, filmed from the opponent’s perspective. In a block-design, fMRI study, 9 novice tennis players watched video clips of tennis play. The main stimulus conditions were (1) serve sequences, (2) non-serve behaviour (ball bouncing) and (3) static control sequences. A button response was required indicating the direction of serve (left or right for serve sequences, middle button for non-serve and static sequences). By comparing responses to the three stimulus conditions, it was possible to identify two groups of brain regions responsive to different components of the task. Areas MT/MST and STS in the posterior part of the temporal lobe responded either to serve and to non-serve stimuli, relative to static controls. Serve sequences produced additional regions of activation in parietal lobe (bilateral IPL, right SPL) and in right frontal cortex (IFGd, IFGv), and these areas were not activated by non-serve sequences. These regions of parietal and frontal cortex have been implicated in a “mirror neuron” network in the human brain. It is concluded that the task of judgement of serve direction produces two different patterns of response: activations in MT/MST and STS concerned with primarily with the analysis of motion and body actions, and activations in parietal and frontal cortex associated specifically with the task of identification of direction of serve
Effects of low dose morphine on perceived sleep quality in patients with refractory breathlessness : a hypothesis generating study
© 2015 Asian Pacific Society of Respirology. Background and objective The management of chronic refractory breathlessness is one of the indications for regular low-dose (≤30 mg/24 h) oral sustained release morphine. Morphine may disrupt sleep in some conditions and improve sleep quality in others. This study aimed to determine any signal of regular, low-dose morphine on perceived sleep disruption due to breathlessness and perceived sleep quality. Methods This is a secondary analysis of data from 38 participants with refractory breathlessness (30 male; 33 with COPD) aged 76 ± 0.9 years who completed a double-blind, randomized, placebo-controlled, cross-over study in which they received 20 mg oral sustained release morphine daily and placebo for 4 days each. Participant ratings of sleep disruption due to breathlessness and perceived sleep quality were obtained daily throughout the 8-day trial. Results Perceived sleep disruption due to breathlessness over the 4-day period ranged between 13% and 32% of participants for placebo and 13% and 26% for morphine, decreasing by each day of the study during the morphine arm. Most participants reported 'very good' or 'quite good' sleep throughout the trial and were less likely to perceive poor sleep quality during the morphine arm (odds ratio = 0.55, 95% confidence interval: 0.34-0.88, P = 0.01). Participants who reported decreased breathlessness during the 4 days on morphine were also likely to report improved sleep quality with morphine (P = 0.039). Conclusion Four days of low-dose morphine improved perceived sleep quality in elderly participants with refractory breathlessness. Regular low-dose morphine targeted to reduce refractory breathlessness may yield associated benefits by reducing sleep disruption and improving sleep quality
Blinded patient preference for morphine compared to placebo in the setting of chronic refractory breathlessness – an exploratory study
Context Patients’ preference for morphine therapy has received little attention in the setting of chronic refractory breathlessness. However, this is one important factor in considering longer term therapy. Objectives The aim of this secondary analysis is to explore blinded patient preference of morphine compared to placebo for this indication and to define any predictors of preference. Methods Data were pooled from three randomized, double-blind, crossover, placebo-controlled studies of morphine (four days each) in chronic refractory breathlessness. Blinded patient preferences were chosen at the end of each study. A multivariable regression model was used to establish patient predictors of preference. Results Sixty-five participants provided sufficient data (60 males; median age 74 years; heart failure 55%, chronic obstructive pulmonary disease 45%; median Eastern Cooperative Oncology Group performance status 2). Forty-three percent of participants preferred morphine (32% placebo and 25% no preference). Morphine preference and younger age were strongly associated: odds ratio = 0.85, 95% confidence interval 0.78, 0.93;
Deceptive body movements reverse spatial cueing in soccer
This article has been made available through the Brunel Open Access Publishing Fund.The purpose of the experiments was to analyse the spatial cueing effects of the movements of soccer players executing normal and deceptive (step-over) turns with the ball. Stimuli comprised normal resolution or point-light video clips of soccer players dribbling a football towards the observer then turning right or left with the ball. Clips were curtailed before or on the turn (-160, -80, 0 or +80 ms) to examine the time course of direction prediction and spatial cueing effects. Participants were divided into higher-skilled (HS) and lower-skilled (LS) groups according to soccer experience. In experiment 1, accuracy on full video clips was higher than on point-light but results followed the same overall pattern. Both HS and LS groups correctly identified direction on normal moves at all occlusion levels. For deceptive moves, LS participants were significantly worse than chance and HS participants were somewhat more accurate but nevertheless substantially impaired. In experiment 2, point-light clips were used to cue a lateral target. HS and LS groups showed faster reaction times to targets that were congruent with the direction of normal turns, and to targets incongruent with the direction of deceptive turns. The reversed cueing by deceptive moves coincided with earlier kinematic events than cueing by normal moves. It is concluded that the body kinematics of soccer players generate spatial cueing effects when viewed from an opponent's perspective. This could create a reaction time advantage when anticipating the direction of a normal move. A deceptive move is designed to turn this cueing advantage into a disadvantage. Acting on the basis of advance information, the presence of deceptive moves primes responses in the wrong direction, which may be only partly mitigated by delaying a response until veridical cues emerge
Palliative management of refractory dyspnea in COPD
COPD is a progressive illness with worldwide impact. Patients invariably reach a point at which they require palliative interventions. Dyspnea is the most distressing symptom experienced by these patients; when not relieved by traditional COPD management strategies it is termed “refractory dyspnea” and palliative approaches are required. The focus of care shifts from prolonging survival to reducing symptoms, increasing function, and improving quality of life. Numerous pharmacological and non-pharmacological interventions can achieve these goals, though evidence supporting their use is variable. This review provides a summary of the options for the management of refractory dyspnea in COPD, outlining currently available evidence and highlighting areas for further investigation. Topics include oxygen, opioids, psychotropic drugs, inhaled furosemide, Heliox, rehabilitation, nutrition, psychosocial support, breathing techniques, and breathlessness clinics
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