30 research outputs found

    Random raman fiber laser based on a twin-core fiber with FBGs inscribed by femtosecond radiation

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    Narrowband Raman lasing in a polarization-maintaining two-core fiber (TCF) is demonstrated. Femtosecond point-by-point inscription of fiber Bragg gratings (FBGs) in individual cores produces a half-open cavity with random distributed feedback. The laser linewidth in the cavity with a single FBG inscribed in one core of the TCF reduced by ∼2 times with respect to the cavity with a fiber loop mirror. It is shown that the inscription of two FBGs in different cores leads to the formation of a Michelson-type interferometer, leading to the modulation of generation spectra near threshold. This technique offers new possibilities for spectral filtering or multi-wavelength generation

    The Effect of Personal Health on the Formation of Human Capital: a Metasystem Approach

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    In article the problem of influence of the personality's health on formation of the human capital is considered. Authors have conducted theoretical researches of the existing knowledge of the human capital and justifications of influence of the personality's health on its formation are given. On the basis of the carried-out analysis it is established that now the personality's health is a significant factor of efficiency of any kind of activity and important quality of the personality, therefore, it can be considered as a factor of formation of the human capital. According to it need of determination of criteria, the indicators of health of the personality influencing formation and development of the human capital was designated

    INNOVATIVE TECHNOLOGIES IN OIL INDUSTRY: INTELLECTUAL EQUIPMENT OF WELLS

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    RETRACTION:The article published in the scientific Journal “Actual Problems of Economics and Law” (2013. No. 2. Pp. 94–100) under the title “Innovative technologies in oil industry: intellectual equipment of wells” under the authorship of R. Sh. Sadykova, L. A. Abdullina, L. I. Gazizullina is withdrawn by an editor with the consent of the publisher and the author.Retraction is due to incorrect borrowing from:1. Aver'yanov D. A. Intellektual'nye sistemy v neftegazovom dele // Neft'. Gaz. Novatsii. 2011. № 11. S. 24–26https://elibrary.ru/item.asp?id=176822652. Eremenko O. V. Effektivnost' razvitiya resursnogo potentsiala neftegazodobyvayushchego predpriyatiya innovatsionnym metodom intellektual'nykh skvazhinnykh sistem // Intellekt. Innovatsii. Investitsii. 2012. № 2. S. 24–27https://www.elibrary.ru/item.asp?id=1864137

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    Polycomplex Carrier for Buccal Mucoadhesion Delivery of Metronidazole

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    Introduction. One of the well-known requirements for buccal drug delivery systems is the demonstration of mucoadhesive properties of the carrier, ensuring retention on the mucosa for a long time with the gradual release of the included drug. It should be noted that one of the advantages of buccal systems compared with oral ones is the absence of the «first pass effect» through the liver.Aim. To carry out a physicochemical and pharmaceutical research of the interpolyelectrolyte complex (IPEC), obtained on the basis of pharmaceutically acceptable polymers – Eudragit® EPO and Noveon® AA-1, in comparison with the physical mixture and individual polymers, as a mucoadhesive delivery system of metronidazole for the treatment of periodontal diseases.Materials and methods. Obtained on the basis of a pair of pharmaceutical polymers (Eudragit® EPO and Noveon® AA-1), two IPEC samples were characterized by elemental analysis, FTIR spectroscopy, and modulated temperature differential scanning calorimetry (mDSC) in comparison with individual polymers and their physical mixtures. The study of swelling ability, bioadhesion and release was carried out in a medium simulating artificial salivary fluid (pH 7.0) at a temperature of 37 ± 0.1 °C. Mucoadhesion of polymer samples and IPEC was studied using a TA.XTplus texture analyzer (Stable Micro Systems, UK). The release of metronidazole (MD) from matrices based on the developed IPEC was studied on a CE 7Smart USP 4 apparatus (Sotax, Switzerland) using the Flow Trough Cell method at a speed a flow of 20 ml/min in an open cycle within 5 hours. The amount of released MD was estimated by UV spectrophotometry on a Lambda 25 instrument (PerkinElmer, USA) at a wavelength of 319 nm.Results and discussion. As a result of studies on the physicochemical and pharmaceutical properties, there was selected the optimal composition of a polycomplex carrier (IPEC 2) based on Eudragit® EPO and Noveon® AA-1, which is characterized by the required bioadhesive properties and the ability of providing controlled release of drug from the tablet matrix (with weight ratio MD/IPEC-2 1:0.5) in conditions mimicking oral cavity environment, which provides the necessary mode of buccal delivery of metronidazole in accordance with Fick's law of diffusion.Conclusion. IPEC 2 is a perspective for use as carrier for buccal controlled delivery of metronidazole

    Raman fiber laser based on dual-core fiber with fiber Bragg grating inscribed by femtosecond radiation

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    Application of femtosecond point-by-point inscription technique make it possible to form fiber Bragg gratings (FBGs) in different cores of multicore fibers as mirrors of laser cavity. In this paper, we present various configurations of Raman laser based on dual-core fiber. Due to the use of the inscribed FBG in the cavity of dual-core fiber, lasing threshold is reduced and the output power stability is increased, comparing to existing schemes
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