The geoaccumulation index and enrichment factor of mercury in mangrove sediment of Port Klang, Selangor, Malaysia.

Mangrove areas are important to the ecosystem. One of its crucial functions is as a sink of pollutants, especially metal ions. However, the accumulation of metals in mangrove sediment can generate negative impacts on plant growth, microbial activity, and soil fertility. Apart from that, the severity of the impact is highly influenced by the type of metal found in the sediment and the quality of sediment itself. One of the metals that have adverse effects on the environment is mercury. The objectives of this study are to determine the concentration and distribution of mercury and to assess the enrichment of mercury in Port Klang mangrove sediment by using geoaccumulation index and enrichment factor. Sediment samples were collected from 30 sampling points that cover Langat River and Klang River estuaries, Lumut Straits, Pulau Klang, and Pulau Indah. During sampling, water parameters such as pH, salinity, electrical conductivity, and total dissolved solids were measured in situ, whereas the total mercury in sediment samples was determined at the laboratory using inductively coupled plasma mass spectrometry. In this study, mercury was found to be concentrated along Lumut Strait especially in the mixing zone near the confluence of Langat River and at the jetty to Pulau Ketam. The geoaccumulation index and enrichment factor (calculated using logarithmized data of the reference element) found that three stations were enriched with mercury. In addition, geoaccumulation index was also observed to be more objective compared to enrichment factor whose results were influenced by the concentration of reference element used

Global, regional, and national incidence of six major immune-mediated inflammatory diseases: findings from the global burden of disease study 2019

Background The causes for immune-mediated inflammatory diseases (IMIDs) are diverse and the incidence trends of IMIDs from specific causes are rarely studied. The study aims to investigate the pattern and trend of IMIDs from 1990 to 2019. Methods We collected detailed information on six major causes of IMIDs, including asthma, inflammatory bowel disease, multiple sclerosis, rheumatoid arthritis, psoriasis, and atopic dermatitis, between 1990 and 2019, derived from the Global Burden of Disease study in 2019. The average annual percent change (AAPC) in number of incidents and age standardized incidence rate (ASR) on IMIDs, by sex, age, region, and causes, were calculated to quantify the temporal trends. Findings In 2019, rheumatoid arthritis, atopic dermatitis, asthma, multiple sclerosis, psoriasis, inflammatory bowel disease accounted 1.59%, 36.17%, 54.71%, 0.09%, 6.84%, 0.60% of overall new IMIDs cases, respectively. The ASR of IMIDs showed substantial regional and global variation with the highest in High SDI region, High-income North America, and United States of America. Throughout human lifespan, the age distribution of incident cases from six IMIDs was quite different. Globally, incident cases of IMIDs increased with an AAPC of 0.68 and the ASR decreased with an AAPC of −0.34 from 1990 to 2019. The incident cases increased across six IMIDs, the ASR of rheumatoid arthritis increased (0.21, 95% CI 0.18, 0.25), while the ASR of asthma (AAPC = −0.41), inflammatory bowel disease (AAPC = −0.72), multiple sclerosis (AAPC = −0.26), psoriasis (AAPC = −0.77), and atopic dermatitis (AAPC = −0.15) decreased. The ASR of overall and six individual IMID increased with SDI at regional and global level. Countries with higher ASR in 1990 experienced a more rapid decrease in ASR. Interpretation The incidence patterns of IMIDs varied considerably across the world. Innovative prevention and integrative management strategy are urgently needed to mitigate the increasing ASR of rheumatoid arthritis and upsurging new cases of other five IMIDs, respectively. Funding The Global Burden of Disease Study is funded by the Bill and Melinda Gates Foundation. The project funded by Scientific Research Fund of Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital (2022QN38)

Groundwater quality and its implications for domestic and agricultural water supplies in a semi-arid river basin of Niger

In the River Goulbi Maradi Basin (RGMB), groundwater is a vital source of drinking water and plays a central role in the region’s socio-economic development. The quality and suitability of groundwater for irrigation and drinking-water remain inadequately understood. We examine hydrochemical analyses of 35 groundwater samples from the shallow alluvial (17) and underlying Continental Hamadien (CH) sandstone (18) aquifers and evaluate these against standard measures of their suitability for drinking water (World Health Organization (WHO) guideline values) and irrigation (i.e., sodium adsorption ratio, sodium percentage, and the residual sodium carbonate). Hydrochemical facies are principally of Na–HCO3 and Na–Cl types. Bivariate plots combined with saturation indices and electrical conductivity monitoring suggest that the main hydrogeochemical processes influencing groundwater quality are cation exchange in the CH aquifer and solute leaching from soils during focused recharge in the alluvial aquifer. 76% (13/17) of groundwater samples from the alluvial aquifer were suitable for irrigation compared to 38% (6/16) of the samples from the CH. The identification of high fluoride concentrations exceeding the WHO drinking-water guideline value (> 1.5 mg/L) in 33% (6/18) of samples from the CH aquifer and 18% (3/17) in the alluvial aquifer, and their respective attribution to the release of fluoride of geogenic origin through cation exchange and local use of fluorapatite fertilisers, provide valuable insight into efforts to address the on-going challenge of fluorosis in the Maradi region of Niger and more widely across African drylands. The health consequences of the widespread observation of Mn in concentrations exceeding the new WHO guideline value (0.08 mg/L) in the alluvial aquifer (6/9 samples), often alongside elevated Fe concentrations, are unclear

Paleochannel groundwater discharge to the River Niger in the Iullemmeden Basin estimated by near- surface geophysics and piezometry

In drylands, groundwater is often the only perennial source of freshwater to sustain domestic water supplies and irrigation. Knowledge of the pathways and dynamics of groundwater discharge and recharge is, therefore, essential to inform sustainable and rational management of limited water resources. The lower valley of the Dallol Maouri in Niger represents a large fossil tributary (i.e. paleochannel) of the River Niger and drains groundwater regionally from the Iullemmeden Basin through coarse-grained Quaternary sediments. The objective of this paper is to quantify groundwater discharge within this paleochannel using piezometry and near-surface geophysics (TDEM: Time Domain Electromagnetics, MRS: Magnetic Resonance Sounding). TDEM and MRS experiments, conducted at 21 sites along 3 transects, show the thickness of the saturated Quaternary alluvium varies from 7 to 19 m with estimated effective porosities ranging from 18 to 38% and a hydraulic conductivity of 0.6–3 × 10–3 m/s. Dense piezometric surveys along drainage channel reveal hydraulic gradients of 0.2–0.3‰ that generate Darcy fluxes of 1000–2000 m3/day (dry season, i.e. minimum value). Paleochannel discharge, which currently provides baseflow to the River Niger, is the focus of local demand to increase access to water for drinking, livestock watering, and supplementary irrigation

Changes in aquifer properties along a seasonal river channel of the Niger Basin: Identifying groundwater recharge pathways in a dryland environment

In drylands of tropical Africa, groundwater plays a fundamental role in alleviating food insecurity and adapting to the effects of climate change. Substantial uncertainty persists in the renewability of groundwater resources in drylands and recharge pathways through the surface geology. Here we characterize the architecture and hydrogeological properties of alluvium and underlying sandstone and crystalline basement rocks along the ephemeral River Goulbi de Maradi in the Iullemmeden Basin of Niger using Magnetic Resonance Soundings (MRS), Time-Domain Electromagnetic (TDEM) soundings, and borehole lithological data. Considerable variations in lithological facies and hydrophysical properties are found along a series of 5 transects perpendicular to the seasonal/ephemeral river channel and adjacent plateaux of the Continental Hamadien (CH) sandstone. The CH aquifer comprises a pebbly sand facies upstream and sandstone clay facies downstream with Farak-type sandstones located at the base of the two facies. Consistent with these variations in facies, the geophysical parameters decrease from 19%, 390 ms, and 800 Ω m upstream to 3%, 160 ms, and 10 Ω m downstream, respectively for effective porosity, relaxation time, and resistivity. The transmissivity and specific yield estimated from the decline of MRS longitudinally also vary from upstream to downstream. The combined use of surface geophysics constrained by lithological borehole logs provides vital insight into groundwater replenishment in this dryland environment

Management of postoperative pain: experience of the Niamey National Hospital, Niger

Maman Sani Chaibou,1 Samuila Sanoussi,2 Rachid Sani,2 Nouhou A Toudou,1 Hadjara Daddy,1 Moussa Madougou,1 Idrissa Abdou,1 Habibou Abarchi,2 Martin Chobli31Department of Anesthesiology and Intensive Care, 2Department of Surgery, The Niamey National Hospital, Niamey, Republic of Niger; 3Department of Anesthesiology, Hubert K Maga University Teaching Hospital, Cotonou, BeninObjective: The aim of this study was to evaluate the management of postoperative pain at the Niamey National Hospital.Methods: A prospective study was conducted in the Department of Anesthesiology and Intensive Care at the Niamey National Hospital from March to June, 2009. Data collected included age, sex, literacy, American Society of Anesthesiologists (ASA) physical status classification, type of anesthesia, type of surgery, postoperative analgesics used, and the cost of analgesics. Three types of pain assessment scale were used depending on the patient's ability to describe his or her pain: the verbal rating scale (VRS), the numerical rating scale (NRS), or the visual analog scale (VAS). Patients were evaluated during the first 48 hours following surgery.Results: The sample included 553 patients. The VRS was used for the evaluation of 72% of patients, the NRS for 14.4%, and the VAS for 13.6%. Of the VRS group, 33.9%, 8.3%, and 2.1% rated their pain as 3 or 4 out of 4 at 12, 24, and 48 hours postoperatively, respectively. For the NRS group, 33.8%, 8.8%, and 2.5% rated their pain as greater than 7 out of 10 at 12, 24, and 48 hours postoperatively, respectively. For the VAS group, 29.3%, 5.4%, and 0% rated their pain as greater than 7 out of 10 at 12, 24, and 48 hours postoperatively, respectively. Conclusion: Postoperative pain assessment and management in developing countries has not been well described. Poverty, illiteracy, and inadequate training of physicians and other health personnel contribute to the underutilization of postoperative analgesia. Analysis of the results gathered at the Niamey National Hospital gives baseline data that can be the impetus to increase training in pain management and to establish standardized protocols.Keywords: postoperative pain, pain scales, Niamey National Hospita