An original gene cluster: Elucidation of genomic organization and gene expression in the 21q24 region-3

in the alignment, above the sequences, and to the length of each sequence, at the end of the line. Dot indicates a common residue with that of the first sequence (bovSERPINA3-1), dash shows a gap, i.e. a position with an insertion-deletion event. Shaded characters indicate selectively conserved residues specific of the sub-group including bovSERPINA3-7 and bovSERPINA3-8. (▼) indicates asparagine (N) residue involved in a potential N-glycosylation site.<p><b>Copyright information:</b></p><p>Taken from "An original gene cluster: Elucidation of genomic organization and gene expression in the 21q24 region"</p><p>http://www.biomedcentral.com/1471-2164/9/151</p><p>BMC Genomics 2008;9():151-151.</p><p>Published online 2 Apr 2008</p><p>PMCID:PMC2373789.</p><p></p

An original gene cluster: Elucidation of genomic organization and gene expression in the 21q24 region-2

characters and the names of loci established for Btau-2.0 genomic sequence assembly are added (when known) below between brackets. The different genes are localized on the four overlapping BAC clones covering approximately 235 Kb. The two question marks indicate the uncertainties of relative location for the genes /and /, respectively. The gene is also shown.<p><b>Copyright information:</b></p><p>Taken from "An original gene cluster: Elucidation of genomic organization and gene expression in the 21q24 region"</p><p>http://www.biomedcentral.com/1471-2164/9/151</p><p>BMC Genomics 2008;9():151-151.</p><p>Published online 2 Apr 2008</p><p>PMCID:PMC2373789.</p><p></p

An original gene cluster: Elucidation of genomic organization and gene expression in the 21q24 region-4

separated on 2D gel electrophoresis and hybridized with specific polyclonal antibodies. Arrows indicate the position of the two first characterized serpins bovSERPINA3-1 and bovSERPINA3-3. Note the linear alignment of spots corresponding to a different extent of phosphorylation of isoforms running with similar Mr on the second dimension. For more detail see the Methods section.<p><b>Copyright information:</b></p><p>Taken from "An original gene cluster: Elucidation of genomic organization and gene expression in the 21q24 region"</p><p>http://www.biomedcentral.com/1471-2164/9/151</p><p>BMC Genomics 2008;9():151-151.</p><p>Published online 2 Apr 2008</p><p>PMCID:PMC2373789.</p><p></p

An original gene cluster: Elucidation of genomic organization and gene expression in the 21q24 region-0

D I. Southern blot analysis of DNA from two overlapping BAC clones bI0123B08 and bI0511D06 digested with the same restriction endonucleases.<p><b>Copyright information:</b></p><p>Taken from "An original gene cluster: Elucidation of genomic organization and gene expression in the 21q24 region"</p><p>http://www.biomedcentral.com/1471-2164/9/151</p><p>BMC Genomics 2008;9():151-151.</p><p>Published online 2 Apr 2008</p><p>PMCID:PMC2373789.</p><p></p

An original gene cluster: Elucidation of genomic organization and gene expression in the 21q24 region-1

Ray boxes, and intron sequences intron 1 to intron 4 by a thin line. The Genbank accession numbers, the size in bases of each gene, mRNAs, exons and introns are listed in the table. The horizontal line in bold type separates the sub-group of the two other genes. The asterisk in intron 2 of and genes indicates the presence of the Bov-B LINE sequence.<p><b>Copyright information:</b></p><p>Taken from "An original gene cluster: Elucidation of genomic organization and gene expression in the 21q24 region"</p><p>http://www.biomedcentral.com/1471-2164/9/151</p><p>BMC Genomics 2008;9():151-151.</p><p>Published online 2 Apr 2008</p><p>PMCID:PMC2373789.</p><p></p

Scatterplot of the first two principal components of DAPC using breeds as prior clusters.

<p>Breeds are labeled inside their 95% inertia ellipses and dots represent individuals. The inset indicates the eigenvalues of the first five principal components.</p

Algerian sheep genotypes (.ped file)

Genotypes obtained with the Illumina OvineSNP50K Genotyping BeadChip (genotype files) for eight Algerian sheep breeds in a Plink format

Algerian sheep genotypes (.map file)

Genotypes obtained with the Illumina OvineSNP50K Genotyping BeadChip (markers files by chromosomes) for eight Algerian sheep breeds in a Plink format

Pair-wise F_ST among Algerian breeds (with confidence intervals at 95%).

<p>Pair-wise F_ST among Algerian breeds (with confidence intervals at 95%).</p

Pair-wise F_ST among Algerian breeds (a) and Italian breeds (b), calculated with a common set of 15 microsatellites^* (with confidence intervals at 95%).

<p>Ba, Bagnolese; Co, Comisana; Ge, Gentile Di Puglia; La, Laticauda; Le, Leccese; Sa, Sarda.</p><p>*the common set of microsatellites was: MAF65, MAF214, OARFCB304, ILST11, OARAE129, OARFCB193, MAF209, OARJMP58, ILST5, OARFCB128, INRA63, BM1824, MAF33, MCM140, BM8125.</p><p>Pair-wise F_ST among Algerian breeds (a) and Italian breeds (b), calculated with a common set of 15 microsatellites^{<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0122667#t003fn002" target="_blank">*</a>} (with confidence intervals at 95%).</p