Is Helicobacter Pylori Associated with a Migraine?

Objective: To determine whether Helicobacter pylori (H. pylori) is associated with migraine headache. Design: Case-control study. Settings: Local tertiary Hospitals in Cairo, Egypt and in HaferAlbaten, Saudi Arabia. Participants: A total of 70 patients with migraine who were 7 to 17 years old and who fulfilled the International Headache Society criteria for migraine and a total of 50 controls without migraine who were matched by the country of origin, age, sex, ethnicity, and socioeconomic status to the 70 migraine cases. Main Outcome Measures: Antibody levels to H. pylori (IgG) and H. pylori stool antigens were compared between the two groups. Results: Significant association was found between H. pylori and migraine and of the total of 70 migraineur cases, 55.7% were positive for H. pylori stool antigen testing compared to 20% in control group (P value=0.0002). Joint pain was reported in 44.3% and 18.0% of cases and controls respectively (P value=0.0034). Conclusion: H. pylori is associated with migraine without aura and may be a causative factor. Moreover, H. pylori may induce joint pain in the migraineur patients

Surveying the views of pupils attending supplementary schools in England

This report is the first part of a wider research project intended to evaluate the role of supplementary school in supporting pupils’ educational progress. This study reports on the first phase of this research An attitude survey to find out what young people think about mainstream and supplementary education, about the core subjects of reading and mathematics, about themselves as learners and about their reasons for attending supplementary school.. Pupil questionnaires were sent to all schools who were successful in being awarded grants from the support service. Schools were asked to administer the questionnaires to ten nominated pupils within the school, although they could give the questionnaire to more than 10 pupils if they chose. Questionnaires were returned from a total of 772 pupils attending 63 supplementary schools in four major cities in England. This is the first study to systematically explore the attitudes of pupils attending supplementary school in England and is the largest ever study of supplementary schools and their pupils

Effects of Selected Wound Dressings and Remedies on Planktonic Bacteria and Bacterial Biofilms of Staphylococcus aureus and Pseudomonas aeruginosa

Abstract: The overall aim of this research is to evaluate the effect of some approaches of treating wounds and the use of wound dressings of on the planktonic bacteria and bacterial biofilms of Staphylococcus aureus and Pseudomonas aeruginosa, two major bacterial species found in wounds. The wound treatments were dressings containing either honey or silver, and commercial hand gels with alcohol. Results indicate that dressings that contain Manuka honey were efficacious against planktonic bacteria of S. aureus, whereas, dressings with silver were most effective against planktonic Pseudomonas aeruginosa. Panaderm (antibiotic) showed the strongest activity against both planktonic S. aureus and P. aeruginosa. The effect of wound treatments on non-established and established bacterial biofilms after 24 and 48 hours after application, show that dressings were effective against the biofilm of S. aureus. However, a non-adherent dressing with Activon Manuka Honey was ineffective against Pseudomonas aeruginosa biofilm. Overall, except for hand gels, the wound remedies tested show remarkable activity against the biofilms of S. aureus and P. aeruginosa

Towards more effective supplementary and mother-tongue schools (in England)

SIGLEAvailable from British Library Document Supply Centre-DSC:m01/41373 / BLDSC - British Library Document Supply Centre2. ed.GBUnited Kingdo

Impact of integrated neuromuscular inhibition technique versus electro-acupuncture stimulation of posterior tibial nerve in males with chronic pelvic pain of myofascial origin

The aim of the study was toexamine theimpactof the integrated neuromuscular inhibition technique and electro-acupuncture stimulation of posterior tibial nerve in malesdiagnosed with chronic pelvic pain of myofascial origin.Sixty male patientswithchronic pelvic painparticipated in this randomized, single-blind, active-controlled trial andthey were randomly dividedinto 3 groups of equal size.The groupA(20 patients)received integrated neuromuscular inhibitiontechnique (INIT) and pelvic floor exercise, the groupB(20 patients) received posterior tibial nerve electroacupuncture using TENS acupuncture as a noninvasive pelvic floor muscle neuromodulation technique and pelvic floor exercise, and the controlgroupC(20 patients)received pelvic floor exercise only. Serum cortisol level(SCL) measurementwas done,and the National Institute of Health Chronic Prostatitis Symptom Index (NIH-CPSI) questionnairescore was usedto assess the severity of symptoms of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).The measurementswere doneat baseline and after the next two months.Comparing the threegroups post treatment,our results show that there arestatistically significant differencesinserum cortisol leveland inthe National Institute The aim of the study was toexamine theimpactof the integrated neuromuscular inhibition technique and electro-acupuncture stimulation of posterior tibial nerve in malesdiagnosed with chronic pelvic pain of myofascial origin.Sixty male patientswithchronic pelvic painparticipated in this randomized, single-blind, active-controlled trial andthey were randomly dividedinto 3 groups of equal size.The groupA(20 patients)received integrated neuromuscular inhibitiontechnique (INIT) and pelvic floor exercise, the groupB(20 patients) received posterior tibial nerve electroacupuncture using TENS acupuncture as a noninvasive pelvic floor muscle neuromodulation technique and pelvic floor exercise, and the controlgroupC(20 patients)received pelvic floor exercise only. Serum cortisol level(SCL) measurementwas done,and the National Institute of Health Chronic Prostatitis Symptom Index (NIH-CPSI) questionnairescore was usedto assess the severity of symptoms of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).The measurementswere doneat baseline and after the next two months.Comparing the threegroups post treatment,our results show that there arestatistically significant differencesinserum cortisol leveland inthe National Institute The aim of the study was toexamine theimpactof the integrated neuromuscular inhibition technique and electro-acupuncture stimulation of posterior tibial nerve in malesdiagnosed with chronic pelvic pain of myofascial origin.Sixty male patientswithchronic pelvic painparticipated in this randomized, single-blind, active-controlled trial andthey were randomly dividedinto 3 groups of equal size.The groupA(20 patients)received integrated neuromuscular inhibitiontechnique (INIT) and pelvic floor exercise, the groupB(20 patients) received posterior tibial nerve electroacupuncture using TENS acupuncture as a noninvasive pelvic floor muscle neuromodulation technique and pelvic floor exercise, and the controlgroupC(20 patients)received pelvic floor exercise only. Serum cortisol level(SCL) measurementwas done,and the National Institute of Health Chronic Prostatitis Symptom Index (NIH-CPSI) questionnairescore was usedto assess the severity of symptoms of chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).The measurementswere doneat baseline and after the next two months.Comparing the threegroups post treatment,our results show that there arestatistically significant differencesinserum cortisol leveland inthe National Institute of Health Chronic Prostatitis Symptom Index (NIH-CPSI) questionnairescorein both group A and B(p0.05).The findings of this research showed a significant reduction ofblood cortisol level and improvementofNIH CPSI questionnaire total valuein men with chronic pelvic pain who used an integrated neuromuscular inhibition technique and percutaneous posterior tibial nerve stimulation, and a non-significant difference in the control groupC.The INIT has superiority overelectro-acupuncture stimulation of the posterior tibial nerve inreducing painand improvingquality of lif

Impact of antenatal oxytocin infusion on neonatal respiratory morbidity associated with elective cesarean section

Introduction : This study was designed to estimate respiratory morbidity associated with elective cesarean section (ECS) and to determine the effect of antenatal oxytocin exposure on this morbidity. Material and methods : Nine hundred and sixty-five neonates ≥ 37 weeks’ gestation delivered by cesarean section during 1 year were included in this retrospective study and classified into two groups according to oxytocin exposure before cesarean deliveries. Respiratory morbidity for each group was recorded and statistically analyzed. Results : Transient tachypnea of newborn (TTN) was significantly more frequent in group II (ECS group) than in group I (cesarean section after oxytocin exposure) (8.19% vs. 2.92%; respectively, p = 0.0006). Mechanical ventilation, continuous positive airway pressure (CPAP) and oxygen therapy were significantly more frequent in group II than in group I (1.78%, 2.14% and 4.28% versus 0.44%, 0.58% and 1.46%, respectively; p = 0.039, and p = 0.033 and p = 0.009, respectively). The number of newborns admitted to the neonatal unit and neonatal intensive care unit (NICU) was significantly higher in group II than in group I (6.41% and 2.14% vs. 2.05% and 0.58%, respectively; p = 0.001 and p = 0.033, respectively). Surfactant, fluid therapies and parenteral nutrition were significantly more frequent in group II than in group I (2.14%, 4.28% and 2.49% vs. 0.15%, 1.46% and 0.73%, respectively; p = 0.001, p = 0.009 and p = 0.02, respectively). Conclusions : Neonatal respiratory morbidity associated with ECS significantly decreased after antenatal oxytocin exposure. A significant reduction of neonatal respiratory morbidity would be achieved if ECS were performed after 39 weeks’ gestation

Diacerein provokes apoptosis, improves redox balance, and downregulates PCNA and TNF-α in a rat model of testosterone-induced benign prostatic hyperplasia: A new non-invasive approach.

One of the most prevalent chronic conditions affecting older men is benign prostatic hyperplasia (BPH), causing severe annoyance and embarrassment to patients. The pathogenesis of BPH has been connected to epithelial proliferation, inflammation, deranged redox balance, and apoptosis. Diacerein (DIA), the anthraquinone derivative, is a non-steroidal anti-inflammatory drug. This study intended to investigate the ameliorative effect of DIA on the prostatic histology in testosterone-induced BPH in rats. BPH was experimentally induced by daily subcutaneous injection of testosterone propionate for four weeks. The treated group received DIA daily for a further two weeks after induction of BPH. Rats' body and prostate weights, serum-free testosterone, dihydrotestosterone, and PSA were evaluated. Prostatic tissue was processed for measuring redox balance and histopathological examination. The BPH group had increased body and prostate weights, serum testosterone, dihydrotestosterone, PSA, and oxidative stress. Histologically, there were marked acinar epithelial and stromal hyperplasia, inflammatory infiltrates, and increased collagen deposition. An immunohistochemical study showed an increase in the inflammatory TNF-α and the proliferative PCNA markers. Treatment with DIA markedly decreased the prostate weight and plasma hormones, improved tissue redox balance, repaired the histological changes, and increased the proapoptotic caspase 3 expression besides the substantial reduction in TNF-α and PCNA expression. In conclusion, our study underscored DIA's potential to alleviate the prostatic hyperplastic and inflammatory changes in BPH through its antioxidant, anti-inflammatory, antiproliferative, and apoptosis-inducing effects, rendering it an effective, innovative treatment for BPH