795 research outputs found
Ultrasound-guided central venous line placement in critically ill patients: is chest X-ray needed to assess post-insertion pneumothorax?
EFFICIENCY OF CERTAIN INSECTICIDES AGAINST NYMPHS OF Bemisia tabaci (GENNADIUS) INFESTING CUCUMBER CULTIVARS UNDER DIFFERENT CLIMATIC CONDITIONS
Two experiments were carried out at the Central Laboratory for Agricultural Climate (CLAC), Agricultural Research Center and the Experimental Research Station attached to the Faculty of Agriculture, Ain shams Univ., Shalakan, Qalyubyia Governorate. The experiments were conducted for two summer seasons in 2015 and 2016 under unheated multi span plastic house and under open field conditions. Both experiments aimed at investigating the effect of certain weather conditions on the impact of three insecticides used for the control of the cotton whitefly, Bemisia tabaci (Gennadius) nymphs on four cucumber cultivars. The aims of the plastic house experiment and open field experiment were to investigate the impact of certain climatic conditions (Temperature (Co), Relative humidity (%) on different insecticides efficiencies used for whitefly control compared to untreated check (without any insecticide application). Lex (Dinotefuran) insecticide was the more effect on the nymphs of B.tabaci inside the plastic house or in the open field followed by Oshin (Thiamethoxam) insecticide. However Bernastar was the lowest efficiency. Concerning effect of climatic conditions, air temperature and relative humidity affected the performance of the three tested insecticides especially during the days with temperature over 35°C
Effects of Noise on Rabbitâs Blood
Experiments are described in which domestic rabbits were deliberately subjected to a daily 3-4 hours noise regime (65 dB) for 18, 28, 40 and 50 days, to determine its effects on the blood. Noise exposure to rabbits caused a general increase in its biochemical parameters such as urea, uric acid, creatinine, cholesterol, and triglycerides, while glucose level decreased significantly. Our results indicate a general decrease of total protein, albumin and globulin levels. The results indicated that noise exposure at split dose could be harmful. It found that recovery period were able to alleviate some of those harmful changes
Enhancement Reinforcing Concrete Beams Using Polypropylene Cord-Knitted Bars
Currently, technical fabrics play a major role in many industries due to their multiple characteristics. The aim of this research was to utilize composite knitted bars to reinforce concrete beams. Six cord-knitted samples with two different polypropylene yarn counts (outer layer) and three different core materials were manufactured and immersed in a local epoxy material (Kemapoxy 150). Composite knitted bars were prepared in this way. Several tests were conducted for fabrics and knitted bar samples. All data were collected and analysed using two different tools: ANOVA test and radar chart area. Finally, three concrete beams with a varying number of cord-knitted bars (one bar, two bars and three bars) were produced. The results indicated that the differences in outer and core yarns for cord-knitted samples have a significant effect on several fabric and bar characteristics. The knitted bars with PP core yarn can be more beneficial for concrete that do does not require high stress, while the knitted bars using glass fibres and polypropylene (50% and 50% PE) as core materials are not appropriate for applications that require more flexibility and extensibility. Reinforced concrete beams were improved significantly with cord-knitted bars, taking into account the number of bars per area, which may cause the minimizing of flexure force through an increase in that number of bars per area
Effects of space plasma on an oxide coating of spacecraft's surface materials
The aim of this paper is to study the properties of the materials for spacecraft surfaces under the effects of simulated low Earth orbit (LEO) plasma environment to understand the effects of charging and discharging phenomena, which are known to take place when spacecraft is moving through space plasma in LEO. Anodized aluminum Al2O3 samples were prepared using electrochemical techniques with different thicknesses to investigate the role of the Al2O3 coating in the charging and discharging phenomena. Penning plasma source is used to generate plasma using Ar gas flowing through the vacuum chamber. The peak current and the voltage waveform associated with charging and discharging processes, when a negatively biased voltage is applied to the substrate, are discussed. The structural properties before and after plasma exposure are investigated through the morphology and optical analyses of the samples. Morphological analyses confirmed the significant contribution of space plasma in the variation of the crystalline structure, and sample characteristics are dependent on the value of the thickness. In addition, the results confirm the variation of optical properties and the microcrystalline structure over the surface of the anodic oxide film
Changes in the lipids of frozen chickens
A szerzĆk fagyasztott, egyes mintĂĄknĂĄl elĆzetesen hĆkezelt egyiptomi -csirke zsĂr- Ă©s bĆrszövetĂ©nek összes zsĂrtartalmĂĄt, peroxid-szĂĄmĂĄt, thiobarbitursav-szĂĄmĂĄt Ă©s szabad zsĂrsavtartalmĂĄt vizsgĂĄltĂĄk. A fagyasztĂĄst â 20 °C-on vĂ©geztĂ©k, a fagyasztott mintĂĄkat â 4 °C-on tĂĄroltĂĄk. MegĂĄllapĂtottĂĄk, hogy a peroxid-szĂĄm, thiobarbitursav-szĂĄm, a szabad zsĂrsav %-os Ă©rtĂ©ke, valamint a lipidtartalom vĂĄltozĂĄsa a zsĂr oxidĂĄciĂłja Ă©s hidrolĂzise a tĂĄrolĂĄs sorĂĄn jelentĆsebben növekedett a hĆkezeletlen mintĂĄkban, mint a hĆkezeitekben. Les auteurs ont Ă©tudiĂ©, dans des Ă©chantillons de poulets dâEgypte, dont quelques-uns avaient subit un traitement thermique prĂ©alable, la teneur en graisse totale du tissus adipeux et de la peau, les valeurs de pĂ©roxyde et dâacide thiobarbiturique ainsi que la teneur en acides libres. La congĂ©lation sâest effectuĂ©e Ă€ -2 0 ° C et l âentreposage des Ă©chantillons congelĂ©s Ă€ -4 ° ĐĄ. On a Ă©tabli que, lors de Iâentreposage, les valeurs de pĂ©roxyde et dâacide thiobarbiturique, le pourcentage dâacides libres ainsi que les variations de la teneur en lipides, Toxydation et Thydrolyse de la graisse, ont augmentĂ© de tagon plus prononcĂ©c dans les Ă©chantillons non traitĂ©s que dans ceux qui avaient subit un traitement thermique
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Chapter 10 - Industry
This chapter provides an update to developments on mitigation in the industry sector since the IPCC (Intergovernmental Panel on Climate Change) Fourth Assessment Report (AR4) (IPCC, 2007), but has much wider coverage. Industrial activities create all the physical products (e.g., cars, agricultural equipment, fertilizers, textiles, etc.) whose use delivers the final services that satisfy current human needs. Compared to the industry chapter in AR4, this chapter analyzes industrial activities over the whole supply chain, from extraction of primary materials (e.g., ores) or recycling (of waste materials), through product manufacturing, to the demand for the products and their services. It includes a discussion of trends in activity and emissions, options for mitigation (technology, practices, and behavioural aspects), estimates of the mitigation potentials of some of these options and related costs, co-benefits, risks and barriers to their deployment, as well as industry-specific policy instruments. Findings of integrated models (long-term mitigation pathways) are also presented and discussed from the sector perspective. In addition, at the end of the chapter, the hierarchy in waste management and mitigation opportunities are synthesized, covering key waste-related issues that appear across all chapters in the Working Group III contribution to the IPCC Fifth Assessment Report (AR5)
Anti-prostate cancer metabolites from the soil-derived Aspergillus neoniveus
Prostate cancer (PCa) ranks as one of the most commonly diagnosed malignancies worldwide. Toxicity, lack of clinical efficacy, and development of resistance phenotypes are the main challenges in the control of prostate malignancies. Notably, castration-resistance prostate cancer (CRPCa) is a highly aggressive and metastatic phenotype of the disease with a poor prognosis and very limited therapeutic options. Herein, we report the isolation and genotypic identification of a soil-derived fungus Aspergillus neoniveus using the PCR-based internal transcribed spacer (ITS) region amplification approach. HPLC/MS investigation of the metabolic profile of the ethyl acetate extract from the fungal biomass revealed tentative identification of forty-five compounds belonging to various chemical classes including Îł-butyrolactones, alkaloids, phenolics, and quinoids. Furthermore, the chromatographic purification of microbial extract enabled the identification of nervonic acid methyl ester (1) for the first time from endophytic fungi, as well as acetyl aszonalenin (2), and butyrolactone II (3) for the first time from A. neoniveus. The chemical frameworks of the isolated compounds were identified via extensive spectral analysis including 1 and 2D NMR and MS. The X-ray crystal structure and absolute configuration of acetyl aszonalenin (2) were also determined. Additionally, screening of in vitro anticancer activity of the fungal extract revealed its potential antiproliferative and anti-migratory activities against five different prostate cancer cells (PC3, PC-3M, DU-145, CWR-R1ca, and 22Rv1), including different cells with the castration-resistance phenotype. Moreover, the isolated metabolites significantly inhibited the proliferation, migration, and colonization of human prostate cancer cells at low micromolar levels, thus providing credence for future investigation of these metabolites in relevant anti-prostate cancer animal models. Furthermore, computational target prediction tools identified the cannabinoid G-protein coupled receptors type 1 (CB1) as a potential biological target mediating, at least in part, the anticancer effects of acetylaszonalenin (2). Moreover, molecular modeling and docking studies revealed a favorable binding pose at the CB1 receptor orthosteric ligand pocket aided by multiple polar and hydrophobic interactions with critical amino acids. In conclusion, the Aspergillus neoniveus-derived prenylated indole alkaloid acetylaszonalenin has promising anticancer activity and is amenable to further hit-to-lead optimization for the control of prostate malignancies via modulating CB1 receptor
Evaluation of Multiplex Nested Polymerase Chain Reaction for Routine Hepatitis C Virus Genotyping in Egyptian Patients
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