Alterations of blood indices associated with low-dose administration of methomyl insecticide for short times to albino rats

The study aimed to investigate haematological and biochemical alterations associated with short-term intraperitoneal sublethal (1/10 LD50, 2 mg/kg body weight) methomyl administration to male albino rats over two and five days, and also the effects of a two-week recovery period. Methomyl administration over five but not two days decreased mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration. A number of blood biochemical parameters increased (serum glucose, cholesterol, triglycerides, urea, uric acid, creatinine) or decreased (globulin); a recovery period returned many entirely or nearly to control levels. Enzyme activities (ALP, ALT, AST) and bilirubin levels increased following methomyl treatment, but again returned to control levels following a recovery period. We conclude that short low doses of methomyl can harm the blood, kidney and liver of rats.Keywords: methomyl insecticide; hematology and biochemical alternations; male rats

Alterations of blood indices associated with low-dose administration of methomyl insecticide for short times to albino rats

The study aimed to investigate haematological and biochemical alterations associated with short-term intraperitoneal sublethal (1/10 LD 50, 2 mg/kg body weight) methomyl administration to male albino rats over two and five days, and also the effects of a two-week recovery period. Methomyl administration over five but not two days decreased mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration. A number of blood biochemical parameters increased (serum glucose, cholesterol, triglycerides, urea, uric acid, creatinine) or decreased (globulin); a recovery period returned many entirely or nearly to control levels. Enzyme activities (ALP, ALT, AST) and bilirubin levels increased following methomyl treatment, but again returned to control levels following a recovery period. We conclude that short low doses of methomyl can harm the blood, kidney and liver of rats

Amman’s Facades Lost between Identity and Veracity; Factors Impacting Facades’ Design

Today`s building façades continuously lose connection to their local identities and contextual surroundings, more attention is required when designing façades in order to come up with designs that synergize with  their unique surroundings. This does not imply that building façades should be approached in a typical traditional manner, but rather that their design should be a result of different factors, interacting and overlapping, and in respect to the physical and non-physical context.  Façades should be designed in respect to high performance, aesthetics and efficient constructability for example, and this in return indicates that variations in façade designs are a positive indication that buildings are responding to their built and natural contexts. Architects and designers should respond to side effects of globalization resulting in the spreading of out of context styles, unresponsive and kitschy, in order to save the visual interest in the city and the beyond  physical meaning of architecture. It is advised here that architects and designers articulate the very meaning of modernity within local architecture and environment. This article tries to discuss various factors impacting façade design generally, relating discussions to the current situation Amman, the metropolis, and its buildings are undergoing. Keywords: Façade design, contemporary façade, local identity, Amman

Regional Planning in Jordan, the Status Quo - Regional Planning in the Jordan Rift Valley

This paper is intended to examine and research a new way of planning on the Jordanian ground, regional planning, a planning approach proven to be highly effective globally on multiple levels but unfortunately not widely practiced in the Arab World. This research paper tries to examine how the area of the Jordan Valley is being administered regionally, and attempts to breakdown and discuss the different elements of this process in a critical manner. Outcomes of the reserch indicate mainly that although this planning approach is implicated to a certain degree; still it is seen as being more sectoral in nature. Keywords: Jordan Rift Valley, Regional Planning, Dead Sea, Master Plan, Sustainability

Efficient and Strategic Resource Allocation for Sustainable Development in Jordan

This research addresses a modern-day major topic; sustainability, and although it is in fact a very vast and wide topic and on every tongue at current times, some aspects of it seem to be left with little exploration in comparison to the other aspects, such as resource allocation. Mainly, this research will go into the importance of resource allocation for sustainable development, with emphasis on infrastructure, financial, human and information resources, and it will address topic related questions, questions like: how much effect has resource allocation on sustainable place promotion? And is it possible to allocate resources on the basis of any priority structure? And most of all, what can we do in Jordan to improve allocation of resources to achieve the desired integrated and long term development. The results basically highlight incorporating the public for achieving equitable resource allocation, and its dependence on concepts of having a priority system not hierarchy for the process of allocation, planning with objectives and introducing new adaptable global concepts to alleviate the current resource allocation condition in Jordan.This research basically recommends that resources should be allocated according to the priorities and objectives concept, objectives that are predetermined and integrated with a holistic vision of how development should be in a certain area, facilitated by a proper national agenda. Also, these priorities and objectives should always be determined according to the locals in the concerned area, and in a way that is environmentally considerate, socially integrated and economically strengthening. Keywords: External and Internal Resources, Decentralization, Community Involvement, Resource Allocation According to Priorities, Accountability, Equally Shared benefits

The Impact of Corporate Governance on Agency Costs in Jordanian Service Companies

The objective of this study investigates the impact of corporate governance (CG) on agency costs (AC) in Jordanian service companies. The analysis is conducted using the random-effects model on a sample of (42) service companies listed in the Amman Stock Exchange, during the period (2012-2018). Independent variables are used (Board Size, CEO Duality, Audit Committee, Managerial Compensation, Dividend, & Leverage). AC are measured by Asset Turnover Ratio (AT), Selling, General & Administrative Expense Ratio (SG&A) & Free Cash Flow (FCF). This study also includes three control variables: firm size, firm growth & firm profitability. The results of this study, according to the AT index, leverage increases AC through decreasing AT ratio, and this indicates that management uses the borrowed funds in an ineffective manner. The results, according to the SG&A index, are that AC caused by squandering the companies resources on managerial privileges and discretionary expenses are low in large companies and in companies that have high profits. While the results, according to the FCF index, are that the separating of the positions of chairman of the board and CEO & dividend decrease AC through decreasing FCF available under management control, and we find AC caused by possible misuse of FCF are more existing in large companies and in companies that have high profits. This study recommends the Jordanian service companies pay a dividend to shareholders and recommends the Jordanian legislative bodies oblige companies to apply some CG mechanisms, instead of compliance or explain approach. An example includes separating the positions of chairman of the board and CEO for their effective role in reducing AC through reducing FCF available under management control

Effect of electromagnetic filed on body weight and blood indices in Albino rats and therapeutic …

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6-(4-Bromo­phen­yl)-3-methyl-7H-1,2,4-triazolo[3,4-b][1,3,4]thia­diazine

In the title compound, C11H9BrN4S, the 1,2,4-triazole ring is essentially planar (r.m.s. deviation = 0.020 Å) and makes a dihedral angle of 29.1 (5)° with the bromo­benzene ring. The 3,6-dihydro-1,3,4-thia­diazine ring adopts a twist-boat conformation. In the crystal, mol­ecules are linked by C—H⋯N inter­actions into sheets lying parallel to the (010) plane. The same N atom accepts two such hydrogen bonds

Light-Triggered Electron Transfer between a Conjugated Polymer and Cytochrome C for Optical Modulation of Redox Signaling

Protein reduction/oxidation processes trigger and finely regulate a myriad of physiological and pathological cellular functions. Many biochemical and biophysical stimuli have been recently explored to precisely and effectively modulate intracellular redox signaling, due to the considerable therapeutic potential. Here, we propose a first step toward an approach based on visible light excitation of a thiophene-based semiconducting polymer (P3HT), demonstrating the realization of a hybrid interface with the Cytochrome c protein (CytC), in an extracellular environment. By means of scanning electrochemical microscopy and spectro-electrochemistry measurements, we demonstrate that, upon optical stimulation, a functional interaction between P3HT and CytC is established. Polymer optical excitation locally triggers photoelectrochemical reactions, leading to modulation of CytC redox activity, either through an intermediate step, involving reactive oxygen species formation, or via a direct photoreduction process. Both processes are triggered by light, thus allowing excellent spatiotemporal resolution, paving the way to precise modulation of protein redox signaling

Biochemical Studies on Albino Rats after Administration of Nitrosamine and the Therapeutic Actions of Vitamin C, Honey Bee or Crushed Citrus Seeds

The current investigation was carried out to study the effect of administration of dibutyl nitrosamine (DBNA) precursors namely: dibutylamine (DBA) and sodium nitrite for eight weeks on some biochemical blood indices of albino rats and the therapeutic action of vitamin C (150 mg/L), honey bee (100 mg/L) or crushed citrus seeds (100 g/Kg diet) against toxicity induced by DBNA. Nitrosamine administration elevated the concentrations of serum glucose, triglycerides, total cholesterol and nonprotein nitrogenous constituents. Activities of serum aspartate aminotransferase (AST), alanine aminotransferase (ALT) and alkaline phosphatase (ALP) were increased also significantly following DBNA treatment to rats for eight weeks, but total protein were decreased. However, honey bee, Vitamin C and crushed citrus seeds were able to modulate the affected values of the previous biochemical parameters, approximately, near to the control values. Our findings suggested that honey bee, Vitamin C and crushed citrus seeds suppresses DBNA induced hepato-renalo-carcinogenesis, maybe, by modulating the antioxidant defense status