6 research outputs found
Weight loss improves biomarkers endothelial function and systemic inflammation in obese postmenopausal Saudi women.
Background: Although postmenopausal associated disorders are important
public health problems worldwide, to date limited studies evaluated the
endothelial function and systemic inflammation response to weight loss
in obese postmenopausal women. Objective: This study was done to
evaluate the endothelial function and systemic inflammation response to
weight loss in obese postmenopausal Saudi women. Material and methods:
Eighty postmenopausal obese Saudi women (mean age 52.64\ub16.13 year)
participated in two groups: Group (A) received aerobic exercise on
treadmill and diet whereas, group (B) received no intervention. Markers
of inflammation and endothelial function were measured before and after
3 months at the end of the study. Results: The values of body mass
index(BMI), interleukin-6 (IL-6), tumor necrosis factor-alpha
(TNF-\u3b1), C-reactive protein (CRP), inter-cellular adhesion
molecule (ICAM-1), vascular cell adhesion molecule (VCAM-1) and
plasminogen activator inhibitor- 1 activity (PAI-1:Ac) were
significantly decreased in group (A), while changes were not
significant in group (B). Also, there were significant differences
between mean levels of the investigated parameters in group (A) and
group (B) after treatment. Conclusion: Weight loss ameliorates
inflammatory cytokines and markers of endothelial function in obese
postmenopausal Saudi women
Impact of weight reduction program on serum alanine aminotransferase activity and immunologic response in obese hepatitis B patients.
Background: Globally, chronic B viral hepatitis (HBV) is a major health
problem. Obesity is a common problem among patients with HBV. Several
studies have reported that obesity is an important risk factor that
alters immune system response in individuals with no underlying cause
of liver disease. However, there is a strong association between BMI
and the human immune system among HBV patients. Objective: This study
was to examine the correlation between body mass index, serum alanine
aminotransferase activity (ALT) and immunologic response in obese
hepatitis B patients. Material and methods: One hundred fifty male
patients with chronic hepatitis B virus, their age ranged from 30 to 45
(38.64 \ub1 7.12) years and their BMI ranged from 30-35 kg/m2. All
Subjects were included in two groups: The first group received weight
reduction program in the form of treadmill aerobic exercises in
addition to diet control whereas the second group received no
therapeutic intervention. Parameters of serum alanine aminotransferase
(ALT), CD3, CD4 and CD8 were quantified; Leukocyte, differential counts
and body mass index (BMI) were measured before and after 3 months at
the end of the study. Results: There was a 24.7%, 36.8%, 30.8%, 40.7%,
28.6%, 25.9%, 33.3% and 14.3 % reduction in mean values of alanine
aminotransferase (ALT), white blood cells, total neutrophil count,
monocytes, CD3, CD4 ,CD8 and BMI respectively in group (A) at the end
of the study. In addition, there were significant differences between
mean levels of the investigated parameters in groups. Conclusion: Based
on our findings, weight loss modulates serum alanine aminotransferase
and immune system parameters of patients with hepatitis B virus
infection
Impact of Mild versus Moderate Intensity Aerobic Walking Exercise Training on Markers of Bone Metabolism and Hand Grip Strength in Moderate Hemophilic A Patients
Background: Patients with hemophilia A have low bone density than healthy controls. It is now widely recognized that physical activity and sports are beneficial for patients with hemophilia. Objective: The aim of this study was to compare the effects of mild and moderate intensity treadmill walking exercises on markers of bone metabolism and hand grip strength in male patients with moderate hemophilia A. Material and Methods: Fifty male patients with moderate hemophilia, their age ranged from 25 to 45 years. The subjects were randomly assigned into 2 equal groups; the first group (A) received moderate intensity aerobic exercise training. The second group (B) received mild intensity aerobic exercise training. Results: There was a 32.1% and 24.8% increase in mean values of Serum Calcium and Hand grip strength respectively and 22.7 % reduction in mean values of parathyroid hormone in moderate exercise training group (A). While, There was a 15.1 % and 15 % increase in mean values of Serum Calcium and Hand grip strength respectively and 10.3 % reduction in mean values of parathyroid hormone in mild exercise training group(B). The mean values of Serum Calcium and Hand grip strength were significantly increased, while the mean values of parathyroid hormone were significantly decreased in both groups .Also, there were significant differences between mean levels of the investigated parameters in group (A) and group (B) after treatment. Conclusion: Moderate intensity aerobic exercise training on treadmill is appropriate to improve markers of bone metabolism and hand grip strength in male patients with hemophilia A.Keywords: Aerobic exercise, Markers of Bone Metabolism, Hand Grip Strength, HemophiliaAfrican Health sciences Vol 14 No. 1 March 201
Aerobic Exercise Training Improves Cardiopulmonary Fitness Among Firefighters
Aim: Firefighters experience short bursts of extreme physical and
psychological stress punctuating long periods of tedium. For short
intervals, the physical demands of firefighting may approach the limits
of human capacity, so there is a need to find the most appropriate type
of exercise training that achieve the best cardiopulmonary fitness in
firefighters that enables them to do their work. The purpose of this
study was to determine changes in cardiopulmonary fitness after aerobic
and anaerobic exercise training in firefighters. Method: Forty
firefighter workers who practiced their job for no less than fifteen
years were enrolled in this study, their age ranged from 32 to 41
years. Participants were included into 2 equal groups; group (A)
received aerobic treadmill walking exercise training for 3 months, at a
frequency of 4 sessions per week. The second group (B) received
anaerobic exercise training for 3 months, at a frequency of 2 sessions
per week. Measurements of systolic blood pressure (SBP), diastolic
blood pressure (DBP), heart rate (HR), minute ventilation (VE) and
Maximum oxygen consumption (VO2max) obtained for both groups before and
after the exercise program. Result: The mean SBP, DBP and HR values
were significantly decreased, where the mean VE and VO2max values were
significantly increased in group (A) after training. The mean SBP, DBP
and HR values were not significant statistically and the mean VE and
VO2max values were significantly increased in group (B) after training.
There were significant differences between mean levels of SBP, DBP ,HR
and VE in group (A) and group (B) after training, where there was no
significant difference between mean levels of VO2max in group (A) and
group (B) after training. Conclusion: Aerobic exercise training is the
most appropriate type of exercise training that achieves the best
cardiopulmonary fitness in firefighters that enables them to do their
work
Impact of Mild versus Moderate Intensity Aerobic Walking Exercise Training on Markers of Bone Metabolism and Hand Grip Strength in Moderate Hemophilic A Patients.
Background: Patients with hemophilia A have low bone density than
healthy controls. It is now widely recognized that physical activity
and sports are beneficial for patients with hemophilia. Objective: To
compare the effects of mild and moderate intensity treadmill walking
exercises on markers of bone metabolism and hand grip strength in male
patients with moderate hemophilia A. Material and Methods: Fifty male
patients with moderate hemophilia, and age range from 25 to 45 years.
The subjects were randomly assigned into 2 equal groups; the first
group (A) received moderate intensity aerobic exercise training. The
second group (B) received mild intensity aerobic exercise training.
Results: There was a 32.1% and 24.8% increase in mean values of serum
calcium and hand grip strength respectively and 22.7 % reduction in
mean values of parathyroid hormone in moderate exercise training group
(A). While there was a 15.1 % and 15 % increase in mean values of Serum
Calcium and Hand grip strength respectively and 10.3 % reduction in
mean values of parathyroid hormone in mild exercise training group(B).
The mean values of serum calcium and hand grip strength were
significantly increased, while the mean values of parathyroid hormone
were significantly decreased in both groups . There were significant
differences between mean levels of the investigated parameters in group
(A) and group (B) after treatment. Conclusion: Moderate intensity
aerobic exercise training on treadmill is appropriate to improve
markers of bone metabolism and hand grip strength in male patients with
hemophilia A