4,036 research outputs found
Current-voltage characteristics of NdFeAsO0.85F0.15 and NdFeAsO0.85 superconductors
The vortex phase diagrams of NdFeAsO0.85F0.15 and NdFeAsO0.85 superconductors
are determined from the analysis of resistivity and current-voltage (I-V)
measurements in magnetic fields up to 9 T. A clear vortex glass to liquid
transition is identified only in the oxygen deficient NdFeAsO0.85, in which I-V
curves can be well scaled onto liquid and glass branches consistent with the
vortex glass theory. With increasing magnetic field, the activation energy U0,
deduced from the Arrhenius plots of resistivity based on the thermally
activated flux-flow model (TAFF), decays more quickly for NdFeAsO0.85F0.15 than
for NdFeAsO0.85. Moreover, the irreversibility field Hirr of NdFeAsO0.85
increases more rapidly than that of NdFeAsO0.85F0.15 with decreasing
temperature. These observations evidence the strong vortex pinning effects,
presumably caused by the enhanced defects and disorders in the oxygen deficient
NdFeAsO0.85. It is inferred that the enhanced defects and disorder can be also
responsible for the vortex glass to liquid transition in the NdFeAsO0.85.Comment: 19 pages, 5 figure
Continuous Generation of Spinmotive Force in a Patterned Ferromagnetic Film
We study, both experimentally and theoretically, the generation of a dc
spinmotive force. By exciting a ferromagnetic resonance of a comb-shaped
ferromagnetic thin film, a continuous spinmotive force is generated.
Experimental results are well reproduced by theoretical calculations, offering
a quantitative and microscopic understanding of this spinmotive force.Comment: 4 pages, 4 figures, accepted to Physical Review Letter
Analysis of Sensitivity, Linearity, Hysteresis, Responsiveness, and Fatigue of Textile Knit Stretch Sensors
Wearable technology is widely used for collecting information about the human body and its movement by placing sensors on the body. This paper presents research into electronic textile strain sensors designed specifically for wearable applications which need to be lightweight, robust, and comfortable. In this paper, sixteen stretch sensors, each with different conductive stretch fabrics, are evaluated: EeonTex (Eeonyx Corporation), knitted silver-plated yarn, and knitted spun stainless steel yarn. The sensors’ performance is tested using a tensile tester while monitoring their resistance with a microcontroller. Each sensor was analyzed for its sensitivity, linearity, hysteresis, responsiveness, and fatigue through a series of dynamic and static tests. The findings show that for wearable applications a subset of the silver-plated yarn sensors had better ranked performance in terms of sensitivity, linearity, and steady state. EeonTex was found to be the most responsive, and the stainless steel yarn performed the worst, which may be due to the characteristics of the knit samples under test
Hospital Mental Health Admissions in Women after Unsuccessful Infertility Treatment and In Vitro Fertilization: An Australian Population-Based Cohort Study
Objective - To examine the association between in vitro fertilization (IVF) and later admission to hospital with a mental health diagnosis in women who remained childless after infertility treatment. Methods - This was a population-based cohort study using linked administrative hospital and registry data. The study population included all women commencing hospital treatment for infertility in Western Australia between the years 1982 and 2002 aged 20–44 years at treatment commencement who did not have a recorded birth by the end of follow-up (15 August 2010) and did not have a hospital mental health admission prior to the first infertility admission (n=6,567). Of these, 2,623 women had IVF and 3,944 did not. We used multivariate Cox regression modeling of mental health admissions and compared women undergoing IVF treatment with women having infertility treatment but not IVF. Results - Over an average of 17 years of follow-up, 411 women in the cohort were admitted to hospital with a mental health diagnosis; 93 who had IVF and 318 who did not. The unadjusted hazard ratio (HR) for a hospital mental health admission comparing women who had IVF with those receiving other infertility treatment was 0.50 (95% confidence interval [CI] 0.40–0.63). After adjustment for age, calendar year and socio-economic status the HR was 0.56 (95% CI 0.44–0.71). Conclusions - IVF treatment is associated with a reduced risk of hospital mental health admissions in women after unsuccessful infertility treatment. This may be explained by the healthy cohort effect
The role of extracellular polymers on Staphylococcus epidermidis biofilm biomass and metabolic activity
Staphylococcus epidermidis is now well established as being a major nosocomial
pathogen, associated with indwelling medical devices. Its major virulence factor is related with
the ability to adhere to indwelling medical devices, with consequent biofilm formation.
The present study aimed to evaluate the role of polysaccharides and proteins on
biofilm biomass and metabolic activity of five S. epidermidis clinical isolates. For this purpose,
S. epidermis biofilms, formed on acrylic coupons, were characterized in terms of total biofilm
biomass, determined through crystal violet assay, cell concentration, established by colony
forming units (CFU) enumeration, and biofilm matrix composition, which was assessed for
polysaccharides and proteins content. Biofilm metabolic activity was evaluated by two distinct
methods: glucose uptake and XTT reduction assays. According to the results, S. epidermidis
strains revealed different abilities for biofilm formation. In fact, some strains were able to form
thicker biofilms than others and this is important because biofilm formation is considered one
of the major virulence factors of S. epidermidis species. S. epidermidis 1457 was the strain that
produced the larger amount of biofilm and strain LE7 was the lowest biofilm producer, and
these were also the highest and the lowest polysaccharides producers, respectively. This
suggests a certain degree of correlation between exopolysaccharides production and total
amount of biomass formed. Besides, comparing the results obtained, in terms of
exopolysaccharides production and biofilm cellular activity, it seems clear that a strong
production of exopolysaccharides can lead to a decrease in the metabolic activity of cells,
which was the case of S. epidermidis 1457. The protein concentration also varied among
strains, with the biofilm matrix of S. epidermidis 9142 presenting a higher concentration of
proteins comparing to the remaining strains. This fact indicates the different levels of
importance that matrix proteins can have on biofilm composition among strains albeit overall,
it is suggested that extracellular protein production it is not a determinant factor for biofilm
total biomass, despite its qualitative value.
In conclusion, this work provided a reliable approach for a better understanding of S.
epidermidis biofilms composition and metabolic activity
Interstitial lung fluid balance in healthy lowlanders exposed to high-altitude
We aimed to assess lung fluid balance before and after gradual ascent to 5,150 m. Lung diffusion capacity for carbon monoxide (DLCO), alveolar-capillary membrane conductance (DmCO) and ultrasound lung comets (ULCs) were assessed in 12 healthy lowlanders at sea-level, and on Day 1, Day 5 and Day 9 after arrival at Mount Everest Base Camp (EBC). EBC was reached following an 8-day hike at progressively increasing altitudes starting at 2,860 m. DLCO was unchanged from sea-level to Day 1 at EBC, but increased on Day 5 (11 ± 10%) and Day 9 (10 ± 9%) vs. sea-level (P ≤ 0.047). DmCO increased from sea-level to Day 1 (9 ± 6%), Day 5 (12 ± 8%), and Day 9 (17 ± 11%) (all P ≤ 0.001) at EBC. There was no change in ULCs from sea-level to Day 1, Day 5 and Day 9 at EBC. These data provide evidence that interstitial lung fluid remains stable or may even decrease relative to at sea-level following 8 days of gradual exposure to high-altitude in healthy humans
Small inhibitor of Bcl-2, HA14-1, selectively enhanced the apoptotic effect of cisplatin by modulating Bcl-2 family members in MDA-MB-231 breast cancer cells
Inhibition or downregulation of Bcl-2 represents a new therapeutic approach to by-pass chemoresistance in cancer cells. Therefore, we explored the potential of this approach in breast cancer cells. Cisplatin and paclitaxel induced apoptosis in a dose-dependent manner in MCF-7 (drug-sensitive) and MDA-MB-231 (drug-insensitive) cells. Furthermore, when we transiently silenced Bcl-2, both cisplatin and paclitaxel induced apoptosis more than parental cells. Dose dependent induction of apoptosis by drugs was enhanced by the pre-treatment of these cells with HA14-1, a Bcl-2 inhibitor. Although the effect of cisplatin was significant on both cell lines, the effect of paclitaxel was much less potent only in MDA-MB-231 cells. To further understand the distinct role of drugs in MDA-MB-231 cells pretreated with HA14-1, caspases and Bcl-2 family proteins were studied. The apoptotic effect of cisplatin with or without HA14-1 pre-treatment is shown to be caspase-dependent. Among pro-apoptotic Bcl-2 proteins, Bax and Puma were found to be up-regulated whereas Bcl-2 and Bcl-x(L) were down-regulated when cells were pretreated with HA14-1 followed by paclitaxel or cisplatin. Enforced Bcl-2 expression in MDA-MB-231 cells abrogated the sensitizing effect of HA14-1 in cisplatin induced apoptosis. These results suggest that the potentiating effect of HA14-1 is drug and cell type specific and may not only depend on the inhibition of Bcl-2. Importantly, alteration of other pro-apoptotic or anti-apoptotic Bcl-2 family members may dictate the apoptotic response when HA14-1 is combined with chemotherapeutic drugs
Effect of Peierls transition in armchair carbon nanotube on dynamical behaviour of encapsulated fullerene
The changes of dynamical behaviour of a single fullerene molecule inside an
armchair carbon nanotube caused by the structural Peierls transition in the
nanotube are considered. The structures of the smallest C20 and Fe@C20
fullerenes are computed using the spin-polarized density functional theory.
Significant changes of the barriers for motion along the nanotube axis and
rotation of these fullerenes inside the (8,8) nanotube are found at the Peierls
transition. It is shown that the coefficients of translational and rotational
diffusions of these fullerenes inside the nanotube change by several orders of
magnitude. The possibility of inverse orientational melting, i.e. with a
decrease of temperature, for the systems under consideration is predicted.Comment: 9 pages, 6 figures, 1 tabl
Superconductivity in a layered cobalt oxyhydrate NaCoO1.3HO
We report the electrical, magnetic and thermal measurements on a layered
cobalt oxyhydrate NaCoO1.3HO. Bulk superconductivity
at 4.3 K has been confirmed, however, the measured superconducting fraction is
relatively low probably due to the sample's intrinsic two-dimensional
characteristic. The compound exhibits weak-coupled and extreme type-II
superconductivity with the average energy gap and the
Ginzburg-Landau parameter of 0.50 meV and 140,
respectively. The normalized electronic specific heat data in the
superconducting state well fit the dependence, suggesting point nodes
for the superconducting gap structure.Comment: 4 pages, 3 figure
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