The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

AIM: The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery. METHODS: This was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin. RESULTS: Overall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P < 0.001). After adjustment, delay was not associated with a lower rate of complete resection (OR 1.18, 95% CI 0.90-1.55, P = 0.224), which was consistent in elective patients only (OR 0.94, 95% CI 0.69-1.27, P = 0.672). Longer delays were not associated with poorer outcomes. CONCLUSION: One in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease

No limite da precarização? : terceirização e trabalho feminino na industria de confecção

Orientador: Angela Maria Carneiro AraujoDissertação (mestrado) - Universidade Estadual de Campinas, Instituto de Filosofia e Ciencias HumanasResumo: Esta pesquisa discute o papel central que a terceirização assumiu na reestruturação produtiva da indústria de confecção ao longo da década de 1990 e os impactos desse processo sobre as trabalhadoras. Para isso, analisa pequenas, médias e grandes empresas localizadas na macro-região de Campinas e São Paulo e toma como estudo de caso a multinacional Levi Strauss do Brasil, situada em Cotia (Região Metropolitana de São Paulo). O foco da análise é a reestruturação realizada por esta empresa, que consistiu no fechamento da sua unidade produtiva e na extemalização da sua produção para uma cooperativa, implantada exclusivamente para confeccionar os seus artigos e para a qual encaminhou suas ex-funcionárias. Verificamos que a terceirização praticada pela Levi's seguiu um movimento generalizado nesse setor, de revitalização de antigas formas de subcontratação e criação de novas, que tiveram como conseqüência a precarização das condições de trabalho e de vida das trabalhadoras. Nesse sentido, fundamentada em uma análise que contempla as relações de gênero, esta pesquisa procura refletir sobre as implicações desse processo sobre a força de trabalho feminina. Discute como essa experiência cooperativista representou para as trabalhadoras que dela participaram uma forma de assa1ariamento disfarçado, repleta de ações e comportamentos despóticos, totalmente contraditórios com os princípios do cooperativismoAbstract: This research discusses the central role that the outsourcing assumed of the garment industry during the decade of 1990, as well as the jmpact of this process over the female workers. For this discussion, it analyses small, medium and big companies loçated in the macro-region of Campinas and São Paulo and takes as a case study the multinational Levi Strauss of Brazil, located in Cotia (São Paulo's metropolitan area). The dissertation focuses on this company's restructuring process, which had as a consequence the closing of its factory and the subcontracting of a cooperative of women workers, who were it' s ex-employees. This cooperative was established exclusively to produce the Levi' s articles. This kind of outsourcing accomplished by Levi' s followed a general model present in this industry's history, and characterized a revitalization of old forms of putting out and the creation of new ones, provoking as a consequence insecure and precarious work conditions for the female workers. In this sense, grounded in a gendered analysis, this research seeks to explore the jmplications of these changes for the women workers. It discusses how this co-operativist experience represented, for the female workers who took part on it, a kind of disguised wage relations, full of despotic actions and behaviors, totally contradictory to the principIes of cooperativismMestradoSociologiaMestre em Sociologi

Neoliberalism and Social Struggles: the emergence of Piqueteros and anti-globalizationmovements inthe neoliberal context

The introduction of neoliberal policies had impacts on social movements, undermining their organizational capacity and resistance. However, since the mid-1990s a number of instances of mobilization against neoliberalism have emerged, among which we highlight two: the piqueteros (movements of the unemployed in Argentina) and the anti-globalization movement. Based on the research we are developing, this article discusses the emergence and the social composition of each, as well as the elements that distinguish them as movements that were formed as a result of, and in reaction to, neoliberalism

Redes de subcontratação e trabalho a domicílio na indústria de confecção: um estudo na região de Campinas Undercontracting networks and household labor in the clothing industry: a study of the Campinas'region

Este artigo tem como propósito discutir as redes de subcontratação e os novos "usos" do trabalho a domicílio como elementos centrais do processo de reestruturação do setor de confecção nos anos 90, bem como seus impactos sobre as condições de trabalho e saúde das mulheres trabalhadoras. Para isso, partimos de uma pesquisa realizada na região de Campinas/SP, que contemplou o estudo de empresas de confecção de pequeno e médio porte, como também uma extensa rede de subcontratação, que tem na sua ponta inferior o trabalho a domicílio. A pesquisa mostra que as mulheres constituem a força de trabalho tradicionalmente subcontratada pelas empresas confeccionistas e ocupam as posições inferiores e mais vulneráveis na cadeia produtiva. Mostra também que o trabalho a domicílio aparece revitalizado, como instrumento central de aumento da produtividade a baixos custos e como forma alternativa de enfrentar a concorrência com grandes empresas do ramo.This article discusses the undercontracting networks and the new "usages" of household labor as central elements of the restructuring processes of the clothing sector in the nineties, as well as their impact on the labor and health conditions of the working women. This is done through research in the Campinas region, State of São Paulo on small and medium sized clothing industries, including the wide undercontracting network, whose lowest point is household labor. Data show that women are the hands traditionally undercontracted by the clothing industries and that they work on the lowest and most vulnerable positions in the productive chain. They also show that household labor looks renewed, as a central instrument of productivity increase at low cost and as an alternative way of entering the competition with the larger industries

International Nosocomial Infection Control Consortiu (INICC) report, data summary of 43 countries for 2007-2012. Device-associated module

We report the results of an International Nosocomial Infection Control Consortium (INICC) surveillance study from January 2007-December 2012 in 503 intensive care units (ICUs) in Latin America, Asia, Africa, and Europe. During the 6-year study using the Centers for Disease Control and Prevention's (CDC) U.S. National Healthcare Safety Network (NHSN) definitions for device-associated health care–associated infection (DA-HAI), we collected prospective data from 605,310 patients hospitalized in the INICC's ICUs for an aggregate of 3,338,396 days. Although device utilization in the INICC's ICUs was similar to that reported from ICUs in the U.S. in the CDC's NHSN, rates of device-associated nosocomial infection were higher in the ICUs of the INICC hospitals: the pooled rate of central line–associated bloodstream infection in the INICC's ICUs, 4.9 per 1,000 central line days, is nearly 5-fold higher than the 0.9 per 1,000 central line days reported from comparable U.S. ICUs. The overall rate of ventilator-associated pneumonia was also higher (16.8 vs 1.1 per 1,000 ventilator days) as was the rate of catheter-associated urinary tract infection (5.5 vs 1.3 per 1,000 catheter days). Frequencies of resistance of Pseudomonas isolates to amikacin (42.8% vs 10%) and imipenem (42.4% vs 26.1%) and Klebsiella pneumoniae isolates to ceftazidime (71.2% vs 28.8%) and imipenem (19.6% vs 12.8%) were also higher in the INICC's ICUs compared with the ICUs of the CDC's NHSN

NEOTROPICAL ALIEN MAMMALS: a data set of occurrence and abundance of alien mammals in the Neotropics

Biological invasion is one of the main threats to native biodiversity. For a species to become invasive, it must be voluntarily or involuntarily introduced by humans into a nonnative habitat. Mammals were among first taxa to be introduced worldwide for game, meat, and labor, yet the number of species introduced in the Neotropics remains unknown. In this data set, we make available occurrence and abundance data on mammal species that (1) transposed a geographical barrier and (2) were voluntarily or involuntarily introduced by humans into the Neotropics. Our data set is composed of 73,738 historical and current georeferenced records on alien mammal species of which around 96% correspond to occurrence data on 77 species belonging to eight orders and 26 families. Data cover 26 continental countries in the Neotropics, ranging from Mexico and its frontier regions (southern Florida and coastal-central Florida in the southeast United States) to Argentina, Paraguay, Chile, and Uruguay, and the 13 countries of Caribbean islands. Our data set also includes neotropical species (e.g., Callithrix sp., Myocastor coypus, Nasua nasua) considered alien in particular areas of Neotropics. The most numerous species in terms of records are from Bos sp. (n = 37,782), Sus scrofa (n = 6,730), and Canis familiaris (n = 10,084); 17 species were represented by only one record (e.g., Syncerus caffer, Cervus timorensis, Cervus unicolor, Canis latrans). Primates have the highest number of species in the data set (n = 20 species), partly because of uncertainties regarding taxonomic identification of the genera Callithrix, which includes the species Callithrix aurita, Callithrix flaviceps, Callithrix geoffroyi, Callithrix jacchus, Callithrix kuhlii, Callithrix penicillata, and their hybrids. This unique data set will be a valuable source of information on invasion risk assessments, biodiversity redistribution and conservation-related research. There are no copyright restrictions. Please cite this data paper when using the data in publications. We also request that researchers and teachers inform us on how they are using the data