Systematic review of antiepileptic drugs’ safety and effectiveness in feline epilepsy

Understanding the efficacy and safety profile of antiepileptic drugs (AEDs) in feline epilepsy is a crucial consideration for managing this important brain disease. However, there is a lack of information about the treatment of feline epilepsy and therefore a systematic review was constructed to assess current evidence for the AEDs’ efficacy and tolerability in cats. The methods and materials of our former systematic reviews in canine epilepsy were mostly mirrored for the current systematic review in cats. Databases of PubMed, CAB Direct and Google scholar were searched to detect peer-reviewed studies reporting efficacy and/or adverse effects of AEDs in cats. The studies were assessed with regards to their quality of evidence, i.e. study design, study population, diagnostic criteria and overall risk of bias and the outcome measures reported, i.e. prevalence and 95% confidence interval of the successful and affected population in each study and in total

International Veterinary Epilepsy Task Force consensus proposal: Medical treatment of canine epilepsy in Europe

In Europe, the number of antiepileptic drugs (AEDs) licensed for dogs has grown considerably over the last years. Nevertheless, the same questions remain, which include, 1) when to start treatment, 2) which drug is best used initially, 3) which adjunctive AED can be advised if treatment with the initial drug is unsatisfactory, and 4) when treatment changes should be considered. In this consensus proposal, an overview is given on the aim of AED treatment, when to start long-term treatment in canine epilepsy and which veterinary AEDs are currently in use for dogs. The consensus proposal for drug treatment protocols, 1) is based on current published evidence-based literature, 2) considers the current legal framework of the cascade regulation for the prescription of veterinary drugs in Europe, and 3) reflects the authors’ experience. With this paper it is aimed to provide a consensus for the management of canine idiopathic epilepsy. Furthermore, for the management of structural epilepsy AEDs are inevitable in addition to treating the underlying cause, if possible

Auswirkungen von verbleitem Ottokraftstoff mit 0,15 g Pb/l ohne Scavenger auf den Betrieb von Ottomotoren. Abschlussbericht

In einer gemeinsamen Untersuchung von Automobil- und Mineraloel-Industrie wurde die Moeglichkeit ueberprueft, ob Otto-Motoren mit einem Benzin mit einem Bleigehalt von 0,15 g Pb/l und ohne Scavenger ohne Schaeden oder Betriebsstoerungen betrieben werden koennen, um somit eine Umweltbelastung durch Scavenger auszuschliessen. Die Untersuchungen haben gezeigt, dass der Verzicht auf Scavenger zum Teil einen negativen Einfluss auf die Ablagerungen im Brennraum und an den Zuendkerzen zur Folge hatte; die Veraenderungen lagen jedoch noch im tolerierbaren Bereich. (HW)In a joint examination by the car and oil industries, the possibility was checked whether petrol engines using petrol with a lead content of 0.15 g Pb/litre and without a scavenger can be used without damage or interruption of operation, in order to exclude environmental pollution by scavengers. The investigations have shown that dispensing with scavengers has an adverse effect on deposits in the combustion space and has consequences to the sparking plugs; however, the changes were in the tolerable range. (HW)SIGLEAvailable from TIB Hannover: RA 1581(463) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Demontage und Verwertung von Kunststoffbauteilen aus Automobilen

A model situation for the waste product utilization of plastics components from automobiles has been compiled, and from this model the expense necessary for the different material recovery steps has been derived. 47% of the overall expense fall to the disassembly and type-oriented separation, 18% fall to transportation and logistics, and only 37% to the real material recovery process. On the basis of this evaluation it is concluded that the average expense for the production of a recycled synthetic material is not higher than the corresponding costs for new materials. In the case of high-quality thermosplastics even a commercial gain is to be expected. (WEN)SIGLEAvailable from TIB Hannover: RN 4481(100) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman

Demontagefreundliche Gestaltung von Automobilen. T. 1

SIGLETIB Hannover: RN 4481(80) / FIZ - Fachinformationszzentrum Karlsruhe / TIB - Technische InformationsbibliothekDEGerman