Improving physical health and reducing substance use in psychosis - randomised control trial (IMPACT RCT): study protocol for a cluster randomised controlled trial

The National Institute for Health Research funds the IMPACT programme at King’s College London and South London and Maudsley NHS Foundation Trust (ref: RP-PG-0606-1049)

A branch-and-bound approach for the single machine maximum lateness stochastic scheduling problem to minimize the value-at-risk

The research in the field of robust scheduling aims at devising schedules which are not sensitive—to a certain extent—to the disruptive effects of unexpected events. Nevertheless, the protection of the schedule from rare events causing heavy losses is still a challenging aim. The paper presents a novel approach for protecting the quality of a schedule by assessing the risk associated to the different scheduling decisions. The approach is applied to a stochastic scheduling problem with a set of jobs to be sequenced on a single machine. The release dates and processing times of the jobs are generally distributed independent random variables, while the due dates are deterministic. A branch-and-bound approach is taken to minimise the value-at-risk of the distribution of the maximum lateness. The viability of the approach is demonstrated through a computational experiment and the application to an industrial problem in the tool making industry