3 research outputs found
Role of Stem Cells in Orthopaedic Surgery: Theoretical Survey
This study aims at analyzing the Stem cell application is a burgeoning field of medicine that is likely to influence the future of orthopaedic surgery. Stem cells are associated with great promise and great controversy. For the orthopaedic surgeon, stem cells may change the way that orthopaedic surgery is practiced and the overall approach of the treatment of musculoskeletal disease. Stem cells may change the field of orthopaedics from a field dominated by surgical replacements and reconstructions to a field of regeneration and prevention. This review will introduce the basic concepts of stem cells pertinent to the orthopaedic surgeon and proceed with a more in depth discussion of current developments in the study of stem cells in orthopaedic surgery. Keywords: Stem cell, orthopaedic, surgery
Calculated adiposity and lipid indices in healthy Arab children as influenced by vitamin D status
BACKGROUND: Both childhood obesity and vitamin D deficiency are common
in the Middle East. This study aims to determine whether the
associations of vitamin D status to traditional anthropometric
parameters hold true for nonconventional measures of adiposity, such as
body adiposity index (BAT), a measure of body fat percentage,
waist-to-hip ratio, waist-to-height ratio (WHtR), and lipid indices, in
apparently healthy Arab children.
METHODS: A total of 4183 apparently healthy Saudi school students (1906
boys; 2277 girls) aged 12 to 17 years were recruited in this
cross-sectional study. Anthropometrics were obtained. Fasting blood
glucose and lipids were measured routinely. Serum 25(OH)D was measured
using chemiluminescence.
RESULTS: In all subjects, age, BAT, waist-to-hip ratio, and high-density
lipoprotein cholesterol (HDL-C) accounted for 4% of the variance in
serum 25(OH)D (P < .001). All adiposity indices were inversely
associated with 25(OH)D, with WHtR being the most inferior in terms of
strength of association. Vitamin D deficiency significantly increased
risk for low HDL-C in all subjects (odds ratio [95% confidence
interval]: 1.70 [1.24-2.3]; P < .001).
CONCLUSION: BAT is significantly associated with 25(OH)D levels in Arab
children. WHtR is inferior than other anthropometric measures of obesity
regarding the strength of association with 25(OH)D. Risk for or low
HDL-C is significantly increased with vitamin D deficiency.
Interventional studies may determine the potential cardioprotective
effects of vitamin D correction in this population. (C) 2016 National
Lipid Association. All rights reserved