21 research outputs found
The Piúma lineament, southern Espirito Santo: structural expression and tectonic significance
Enraizamento de estacas de espécies de maracujazeiro (Passiflora spp.) no inverno e no verão
Avaliação do desenvolvimento de maracujá-doce (Passiflora alata Dryander) propagado por estaquia e por semente em condições de pomar comercial
Identificação de espécies de Colletotrichum associados à antracnose em plantas de atemóia e colonização do fungo nos frutos
Relationship between the prevalence of antibodies to hepatitis B core antigen and arbovirus in fishermen from the Ribeira Valley, Brazil
Phytoplankton of two rivers in the eastern Amazon: characterization of biodiversity and new occurrences
Transcriptome analysis of the acoelomate human parasite Schistosoma mansoni
Schistosoma mansoni is the primary causative agent of schistosomiasis, which affects 200 million individuals in 74 countries. We generated 163,000 expressed-sequence tags (ESTs) from normalized cDNA libraries from six selected developmental stages of the parasite, resulting in 31,000 assembled sequences and 92% sampling of an estimated 14,000 gene complement. By analyzing automated Gene Ontology assignments, we provide a detailed view of important S. mansoni biological systems, including characterization of metazoa-specific and eukarya-conserved genes. Phylogenetic analysis suggests an early divergence from other metazoa. The data set provides insights into the molecular mechanisms of tissue organization, development, signaling, sexual dimorphism, host interactions and immune evasion and identifies novel proteins to be investigated as vaccine candidates and potential drug targets