482 research outputs found

    Energia metabolizåvel de raçÔes peletizadas e fareladas contendo diferentes níveis de glicerina para frangos de corte.

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    A glicerina bruta Ă© um coproduto resultante da produção de biodiesel que apresenta a molĂ©cula de glicerol em sua composição. AlĂ©m de sua utilização como fonte de energia na nutrição animal o glicerol pode melhorar a qualidade dos peletes e reduzir o pĂł das dietas. Portanto Objetivou-se avaliar o efeito da inclusĂŁo de nĂ­veis de glicerina em raçÔes com diferentes formas fĂ­sicas para frangos de corte. Foram utilizados 384 pintos de corte, machos da linhagem Cobb 500, distribuĂ­dos em delineamento experimental inteiramente casualizado em arranjo fatorial 4 x 2 (quatro nĂ­veis de glicerina bruta ? 0, 4, 8 e 12% e duas formas fĂ­sicas de raçÔes ? peletizada e farelada ), com 8 repetiçÔes de 6 aves por unidade experimental, durante o perĂ­odo de 14 a 24 dias de idade. Foram avaliadas a energia metabolizĂĄvel aparente (EMA) e a energia metabolizĂĄvel aparente corrigida para o balanço de nitrogĂȘnio (EMAn), utilizando a metodologia da coleta total de excretas. A partir do consumo de ração e da produção de excretas foram calculados os valores de EMA e EMAn por meio de equaçÔes. Foi encontrado efeito significativo para a interação nĂ­veis de glicerina bruta e forma fĂ­sica da ração. A inclusĂŁo de glicerina bruta em dietas fareladas apresentou efeito quadrĂĄtico sobre a EMA e EMAn, e a peletização de dietas sem inclusĂŁo de glicerina melhorou EMA e EMAn. É indicado o uso de atĂ© 5,86% e 5,16% de glicerina bruta como meio de aumentar os valores de energia metabolizĂĄvel em dietas fareladas. The crude glycerin is a byproduct from the production of biodiesel which presents the glycerol molecule in its composition . In addition to its use as an energy source in animal nutrition glycerol can improve the quality of the pellets from the powder and reducing diets. So was aimed to evaluate the effect of adding levels of glycerin in diets with different physical forms for broilers. 384 broiler chicks male Cobb 500 were used , distributed in a completely randomized design in a factorial arrangement of 4 x 2 ( four levels of crude glycerin: 0 , 4 , 8 and 12 %) and two physical forms of diets ( pellet and mash), with 8 replicates of 6 birds per experimental unit during the period 14-24 days of age . Apparent metabolizable energy (AME) and apparent metabolizable energy corrected for the balance of nitrogen (AMEn ) were evaluated using the method of total excreta collection. From the feed consumption and the production of the excreta AME and AME were calculated by equations. Significant effect was found for the interaction levels of crude glycerin and physical form of the diet. The inclusion of crude glycerin on dry diets showed a quadratic effect on the AME and AMEn , and pelleting diets without adding glycerin also improved the energy values. The use up to 5.86 % and 5.16 % crude glycerin, increasing metabolizable energy values in mash diets

    Prebiotic composed of yeast (Saccharomyces cerevisiae) cell wall improves performance in broiler diets.

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    Abstract: This research aimed to evaluate the influence of a commercial prebiotic in different concentrations upon several parameters. To carry out the experiment, 640 male one-day-old broiler chicks were distributed in four treatments (0, 0.5, 1.0, and 1.5 kg/ton of yeast cell wall) with eight replicates of 20 birds per experimental unit, in randomized blocks. Prebiotic effects were assessed on performance, carcass yield and prime cuts, in addition to the litter quality (its content of nitrogen and phosphorus). There were significant improvements for weight gain and feed conversion ratio in experimental growth periods. However, prebiotic level at 1.0 kg/ton is enough to provide improvement in performance and similar yield parameters than the control group. Also, 1.5 kg/ton prebiotic inclusion in the diet promotes environmental benefits by reducing the phosphorus amount in the litter by 51%. Above 1.0 kg/ton prebiotic addition in broiler diets can be safely recommended, because it promotes both performance and environmental benefits

    Multiplicity dependence of jet-like two-particle correlations in p-Pb collisions at sNN\sqrt{s_{NN}} = 5.02 TeV

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    Two-particle angular correlations between unidentified charged trigger and associated particles are measured by the ALICE detector in p-Pb collisions at a nucleon-nucleon centre-of-mass energy of 5.02 TeV. The transverse-momentum range 0.7 <pT,assoc<pT,trig< < p_{\rm{T}, assoc} < p_{\rm{T}, trig} < 5.0 GeV/cc is examined, to include correlations induced by jets originating from low momen\-tum-transfer scatterings (minijets). The correlations expressed as associated yield per trigger particle are obtained in the pseudorapidity range ∣η∣<0.9|\eta|<0.9. The near-side long-range pseudorapidity correlations observed in high-multiplicity p-Pb collisions are subtracted from both near-side short-range and away-side correlations in order to remove the non-jet-like components. The yields in the jet-like peaks are found to be invariant with event multiplicity with the exception of events with low multiplicity. This invariance is consistent with the particles being produced via the incoherent fragmentation of multiple parton--parton scatterings, while the yield related to the previously observed ridge structures is not jet-related. The number of uncorrelated sources of particle production is found to increase linearly with multiplicity, suggesting no saturation of the number of multi-parton interactions even in the highest multiplicity p-Pb collisions. Further, the number scales in the intermediate multiplicity region with the number of binary nucleon-nucleon collisions estimated with a Glauber Monte-Carlo simulation.Comment: 23 pages, 6 captioned figures, 1 table, authors from page 17, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/161

    Multi-particle azimuthal correlations in p-Pb and Pb-Pb collisions at the CERN Large Hadron Collider

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    Measurements of multi-particle azimuthal correlations (cumulants) for charged particles in p-Pb and Pb-Pb collisions are presented. They help address the question of whether there is evidence for global, flow-like, azimuthal correlations in the p-Pb system. Comparisons are made to measurements from the larger Pb-Pb system, where such evidence is established. In particular, the second harmonic two-particle cumulants are found to decrease with multiplicity, characteristic of a dominance of few-particle correlations in p-Pb collisions. However, when a âˆŁÎ”Î·âˆŁ|\Delta \eta| gap is placed to suppress such correlations, the two-particle cumulants begin to rise at high-multiplicity, indicating the presence of global azimuthal correlations. The Pb-Pb values are higher than the p-Pb values at similar multiplicities. In both systems, the second harmonic four-particle cumulants exhibit a transition from positive to negative values when the multiplicity increases. The negative values allow for a measurement of v2{4}v_{2}\{4\} to be made, which is found to be higher in Pb-Pb collisions at similar multiplicities. The second harmonic six-particle cumulants are also found to be higher in Pb-Pb collisions. In Pb-Pb collisions, we generally find v2{4}≃v2{6}≠0v_{2}\{4\} \simeq v_{2}\{6\}\neq 0 which is indicative of a Bessel-Gaussian function for the v2v_{2} distribution. For very high-multiplicity Pb-Pb collisions, we observe that the four- and six-particle cumulants become consistent with 0. Finally, third harmonic two-particle cumulants in p-Pb and Pb-Pb are measured. These are found to be similar for overlapping multiplicities, when a âˆŁÎ”Î·âˆŁ>1.4|\Delta\eta| > 1.4 gap is placed.Comment: 25 pages, 11 captioned figures, 3 tables, authors from page 20, published version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/87

    The Role of Methylation in the Intrinsic Dynamics of B- and Z-DNA

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    Methylation of cytosine at the 5-carbon position (5mC) is observed in both prokaryotes and eukaryotes. In humans, DNA methylation at CpG sites plays an important role in gene regulation and has been implicated in development, gene silencing, and cancer. In addition, the CpG dinucleotide is a known hot spot for pathologic mutations genome-wide. CpG tracts may adopt left-handed Z-DNA conformations, which have also been implicated in gene regulation and genomic instability. Methylation facilitates this B-Z transition but the underlying mechanism remains unclear. Herein, four structural models of the dinucleotide d(GC)5 repeat sequence in B-, methylated B-, Z-, and methylated Z-DNA forms were constructed and an aggregate 100 nanoseconds of molecular dynamics simulations in explicit solvent under physiological conditions was performed for each model. Both unmethylated and methylated B-DNA were found to be more flexible than Z-DNA. However, methylation significantly destabilized the BII, relative to the BI, state through the Gp5mC steps. In addition, methylation decreased the free energy difference between B- and Z-DNA. Comparisons of α/γ backbone torsional angles showed that torsional states changed marginally upon methylation for B-DNA, and Z-DNA. Methylation-induced conformational changes and lower energy differences may contribute to the transition to Z-DNA by methylated, over unmethylated, B-DNA and may be a contributing factor to biological function
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