Post-female-circumcision clitoral epidermal inclusion cyst: a case report and a review of literature

Cysts involving the female external genitalia are rare. These cysts are either congenital or acquired. Iatrogenic epidermoid cysts have been reported after female genital mutilation, which is common in some parts of Africa and the Middle East. We report a case of acquired epidermoid inclusion cyst of the clitoris following female circumcision in a 5-year-old girl. The cyst was surgically excised and histopathologic evaluation revealed an epidermal-type inclusion cyst. Keywords: complication, epidermal inclusion cyst, female circumcisio

Synthesis and Characterization of Some New Metals Complexes of [N-(4-Nitrobenzoyl Amino)-Thioxomethyl] Phenylalanine

A new ligand [N-(4-nitrobenzoylamino)-thioxomethyl] phenylalanine is synthesized by reaction of 4-nitrobenzoyl isothiocyanate with phenylalanine (1:1). It is characterized by micro elemental analysis (C.H.N.S.), FT-IR, (UV-Vis) and 1H and 13CNMR spectra. Some metals ions complexes of this ligand were prepared and characterized by FT-IR, UV-Visible spectra, conductivity measurements, magnetic susceptibility and atomic absorption. From results obtained, the following formula [M(NBA)2] where M2+ = Mn, Co, Ni, Cu, Zn, Pd, Cd and Hg, the proposed molecular structure for these complexes as tetrahedral geometry, except copper and palladium complexes are have square planer geometry

Histological and Biochemical Effects of Diazinon on Liver and Kidney of Rabbits.

Abstract: The present study was carried out to investigate the effect of diazinon on histological and biochemical aspect of liver and kidney of rabbit. Diazinon induced blood vessel congestion, leucocytic infiltrations in the liver parenchyma in addition to cytoplasmic vacuolation, fatty degeneration and pyknotic nuclei in the hepatocytes. On the other hand, renal damage was observed in the kidneys of treated rabbits. Renal tissues showed hypertrophied glomeruli, destructive of its lining epithelia. Renal blood vessels were congested and the inter-tubular spaces were filled with red blood cells. Biochemical investigation proved that treatment with diazinon for 4 weeks induced a significant increase in ALT, AST, creatinine and blood urea. Finally, the investigators concluded that diazinon toxicity induced hepatocellular and renal damage

WEB-BASED DUPLICATE RECORDS DETECTION WITH ARABIC LANGUAGE ENHANCEMENT

Sharing data between organizations has growing importance in many data mining projects. Data from various heterogeneous sources often has to be linked and aggregated in order to improve data quality. The importance of data accuracy and quality has increased with the explosion of data size. The first step to ensure the data accuracy is to make sure that each real world object is represented once and only once in a certain dataset which called Duplicate Record Detection (DRD). These data inaccuracy problems exist due to due to several factors including spelling, typographical and pronunciation variation, dialects and special vowel and consonant distinction and other linguistic characteristics especially with non-Latin languages like Arabic. In this paper, an English/Arabic enabled web-based framework is designed and implemented which considers the user interaction to add new rules, enrich the dictionary and evaluate results is an important step to improve system’s behavior. The proposed framework allows the processing on both single language dataset and bi-lingual dataset. The proposed framework is implemented and verified empirically in several case studies. The comparison results showed that the proposed system has substantial improvements compared to known tools

Cephalometric norms for the Saudi children living in the western region of Saudi Arabia: a research report

BACKGROUND: Previous studies have established specific cephalometric norms for children with different ethnic backgrounds, showing different facial features for each group. Up till now, there is a paucity of information about the cephalometric features of Saudi children living in the western region of Saudi Arabia, who have distinct social and climatic characteristics. The aim of the present study was to establish cephalometric norms for children living in the western region of Saudi Arabia. METHODS: A total of 62 lateral cephalometric radiographs of Saudis (33 females and 29 males; aged 9–12 years) having good facial proportions and Class I dental occlusion, were traced and analyzed. Using the t-test, the mean value, standard deviation and the range of 20 angular and linear variables were calculated and compared to norms of adult Saudis living in the Western region of Saudi Arabia using the t-test. Male and female groups were also compared using the t- test. RESULTS: Saudi children tend to have a significantly shorter and lower face height, a larger angle of convexity, and more proclined and protruded incisors when compared with adult Saudis (P < 0.05). There were no statistically significant differences between male and female groups. CONCLUSION: Saudi children have distinct cephalometric features, which should be used as a reference in the orthodontic treatment of young Saudi patients

Coral Research and Nursery Farm Project

In the framework of the Coral Management Plan for the North Field Expansion Project (NFE) and North Field Production Sustainability Project (NFPS), Qatargas has partnered with the Environmental Science Center (ESC) to develop the first land-based coral nursery in Qatar. This nursery plan includes the extraction of 1000 corals' colonies from the NFPS and NFE pipeline corridors, north of Ras Laffan, and hence their transportation to the nursery facility, rehabilitation under controlled husbandry conditions, fragmentation, out-plantation to carefully selected recipient sites and long-term monitoring (up to 48 months). The first two batches of 200 corals were extracted in March and outplanted in April 2021. Results of the first two monitoring events, after 44 and 66 days, were quite encouraging for the seven coral genera tested. Attachment success was very high, with 92% to 97% of the outplanted fragments being detected during monitoring. No bleaching, disease or mortality was recorded so far. The coral propagation methods used in this project (i.e., fragmentation, husbandry and outplanting), although widely used, have been tested with a restricted number of branching coral species and usually in in-situ nurseries. Our project is among the first to apply this type of approach (land-based nursery) to reef restoration in the Arabian Gulf

The mechanisms by which polyamines accelerate tumor spread

Increased polyamine concentrations in the blood and urine of cancer patients reflect the enhanced levels of polyamine synthesis in cancer tissues arising from increased activity of enzymes responsible for polyamine synthesis. In addition to their de novo polyamine synthesis, cells can take up polyamines from extracellular sources, such as cancer tissues, food, and intestinal microbiota. Because polyamines are indispensable for cell growth, increased polyamine availability enhances cell growth. However, the malignant potential of cancer is determined by its capability to invade to surrounding tissues and metastasize to distant organs. The mechanisms by which increased polyamine levels enhance the malignant potential of cancer cells and decrease anti-tumor immunity are reviewed. Cancer cells with a greater capability to synthesize polyamines are associated with increased production of proteinases, such as serine proteinase, matrix metalloproteinases, cathepsins, and plasminogen activator, which can degrade surrounding tissues. Although cancer tissues produce vascular growth factors, their deregulated growth induces hypoxia, which in turn enhances polyamine uptake by cancer cells to further augment cell migration and suppress CD44 expression. Increased polyamine uptake by immune cells also results in reduced cytokine production needed for anti-tumor activities and decreases expression of adhesion molecules involved in anti-tumor immunity, such as CD11a and CD56. Immune cells in an environment with increased polyamine levels lose anti-tumor immune functions, such as lymphokine activated killer activities. Recent investigations revealed that increased polyamine availability enhances the capability of cancer cells to invade and metastasize to new tissues while diminishing immune cells' anti-tumor immune functions

Management and outcomes of gastrointestinal congenital anomalies in low, middle and high income countries: Protocol for a multicentre, international, prospective cohort study

Introduction Congenital anomalies are the fifth leading cause of death in children <5 years of age globally, contributing an estimated half a million deaths per year. Very limited literature exists from low and middle income countries (LMICs) where most of these deaths occur. The Global PaedSurg Research Collaboration aims to undertake the first multicentre, international, prospective cohort study of a selection of common congenital anomalies comparing management and outcomes between low, middle and high income countries (HICs) globally. Methods and analysis The Global PaedSurg Research Collaboration consists of surgeons, paediatricians, anaesthetists and allied healthcare professionals involved in the surgical care of children globally. Collaborators will prospectively collect observational data on consecutive patients presenting for the first time, with one of seven common congenital anomalies (oesophageal atresia, congenital diaphragmatic hernia, intestinal atresia, gastroschisis, exomphalos, anorectal malformation and Hirschsprung''s disease). Patient recruitment will be for a minimum of 1 month from October 2018 to April 2019 with a 30-day post-primary intervention follow-up period. Anonymous data will be collected on patient demographics, clinical status, interventions and outcomes using REDCap. Collaborators will complete a survey regarding the resources and facilities for neonatal and paediatric surgery at their centre. The primary outcome is all-cause in-hospital mortality. Secondary outcomes include the occurrence of postoperative complications. Chi-squared analysis will be used to compare mortality between LMICs and HICs. Multilevel, multivariate logistic regression analysis will be undertaken to identify patient-level and hospital-level factors affecting outcomes with adjustment for confounding factors. Ethics and dissemination At the host centre, this study is classified as an audit not requiring ethical approval. All participating collaborators have gained local approval in accordance with their institutional ethical regulations. Collaborators will be encouraged to present the results locally, nationally and internationally. The results will be submitted for open access publication in a peer reviewed journal