One-pot synthesis of a chitosan-based hydrogel as a potential device for magnetic biomaterial

Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)This describes the cross-linking/co-polymerization reaction of chitosan ( CS), acrylic acid (AAc), and N, N'-methylenebisacrylamide (MBA) in the presence of citrate-covered-gamma-Fe(2)O(3) nanoparticules. A gelling process was verified by means of spectroscopic methods; Fourier transform infrared (FT-IR) and solid-state (13)C-CP/MAS nuclear magnetic resonance (NMR). The corresponding signals of the gelling process, in the (13)C NMR spectra, for the magnetic hydrogel were shifted to lower values due to embedding of the citrate-covered-gamma-Fe(2)O(3) nanoparticules. The X-ray diffraction (XRD) confirmed that the crystallinity of the magnetic hydrogel exhibited a different crystalline structure to that without magnetic properties. The Mossbauer and magnetization analysis revealed that the magnetic hydrogel displays a high lattice strain, due to bonded iron atom covalence and superparamagnetism. From scanning electronic microscope (SEM) micrographs, no separation phase coexists between the magnetic nanoparticules and cross-linked hydrogel, indicating an excellent dispersion throughout the hydrogel. The swelling rate was dependent on the cross-linking degree of the hydrogel and ionic strength of the aqueous solution. (c) 2009 Elsevier B.V. All rights reserved.3211726362642Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)FAPESP [2008/00285-7

Effect of starch type on miscibility in poly(ethylene oxide) (PEO)/starch blends and cytotoxicity assays

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)This study reports results on the miscibility of polymer blends based on PEO and different starches (unmodified, cationic, and hydrophobic) and their respective cytotoxicity. Films of PEO/starch blends at different weight ratios (95/05, 90/10, 80/20, 70/30, 65/35, and 60/40), as well as films of pure PEO as control, were prepared by casting methodology. Several techniques, such as SEM, WAXS, FTIR, and FT-Raman spectroscopy were used in this study for evaluating blend miscibility. The results revealed that the miscibility of such blends is dependent on the type of starch used. Regarding the PEO/unmodified starch blends, it was concluded that the system is miscible in the ratio range from 90/10 to 65/35. Although the PEO/hydrophobic starch blends are miscible in all the studied range, blends of PEO and cationic starch are immiscible, regardless the blend ratio. The different samples presented distinct cytotoxic behaviors. PEO and hydrophobic starch presented no relevant toxicity (CC(50/72)>2.5 mg/mL). Otherwise, the cationic starch was the most harmful for the cells. The blends presented cytotoxicity values between those of PEO and cationic starch. (C) 2010 Elsevier B.V. All rights reserved.312443451Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)CNPq [308611/2006-3

O papel da equipe de enfermagem no centro de atenção psicossocial El papel del equipo de enfermería en el centro de atención psicosocial The nursing team role in the psychosocial attention center

Pesquisa qualitativa, exploratória-descritiva, desenvolvida no ano de 2008, em um Centro de Atenção Psicossocial II e ad de um município da região metropolitana de Curitiba. OBJETIVO: conhecer o papel da equipe de enfermagem junto à equipe multidisciplinar do Centro de Atenção Psicossocial. Os sujeitos foram dois enfermeiros e três auxiliares de enfermagem. Os dados foram coletados por meio de entrevista semiestruturada e organizados em categorias temáticas: As especificidades da assistência no Centro de Atenção Psicossocial e O papel da equipe de enfermagem no Centro de Atenção Psicossocial. Os profissionais de enfermagem reconhecem que o CAPS representa avanço na qualidade da assistência em saúde mental ao considerar o tratamento humanizado e as possibilidades de ressocialização em contraposição ao modelo hospitalocêntrico. Entretanto, é preciso considerar que há uma confusão em relação ao seu papel enquanto membro da equipe multiprofissional desse serviço.<br>Pesquisa cualitativa, exploratoria-descriptiva, desarrollada en el año 2008, en un Centro de Atención Psicosocial II y ad de un municipio de la región metropolitana de Curitiba. OBJETIVO: conocer el papel del equipo de Enfermería junto al equipo multidisciplinar del Centro de Atención Psicosocial. Los sujetos fueron dos enfermeros y tres auxiliares de Enfermería. Los datos fueron colectados por medio de una entrevista semi-estructurada y organizados en categorías temáticas: Las especificaciones de la asistencia en el Centro de Atención Psicosocial y El papel del equipo de Enfermería en el Centro de Atención Psicosocial. Los profesionales de Enfermería reconocen que el CAPS representa el progreso en la cualidad de la asistencia en salud mental al considerar el tratamiento humanizado y las posibilidades de resocialización en contraposición al modelo hospitalocéntrico. Es necesario considerar que hay una confusión con relación a su papel en lo que se refiere a los miembros del equipo multiprofesional de ese servicio.<br>Qualitative Descriptive Exploratory Research developed in 2008 at Psychosocial Attention Center II and ad located in Curitiba metropolitan region. OBJECTIVE: understand the nursing team role along with the Psychosocial Attention Center multidisciplinary team. The participants were two Registered Nurses and three Auxiliary Nurses. The data was collected by a semi-structured interview and organized in thematic categories: The Psychosocial Attention Center Assistance Specificities and The Nursing Team Role at the Psychosocial Attention Center. The Nursing professionals recognize that CAPS represents a quality improvement in mental health assistance considering a humanized treatment and resocialization possibilities, as opposed to the hospital-centric model. However, it is necessary to consider there is some confusion in relation to the professional role as a multiprofessional team for this service