83 research outputs found
Avalanche amplification of a single exciton in a semiconductor nanowire
Interfacing single photons and electrons is a crucial ingredient for sharing
quantum information between remote solid-state qubits. Semiconductor nanowires
offer the unique possibility to combine optical quantum dots with avalanche
photodiodes, thus enabling the conversion of an incoming single photon into a
macroscopic current for efficient electrical detection. Currently, millions of
excitation events are required to perform electrical read-out of an exciton
qubit state. Here we demonstrate multiplication of carriers from only a single
exciton generated in a quantum dot after tunneling into a nanowire avalanche
photodiode. Due to the large amplification of both electrons and holes (>
10^4), we reduce by four orders of magnitude the number of excitation events
required to electrically detect a single exciton generated in a quantum dot.
This work represents a significant step towards single-shot electrical read-out
and offers a new functionality for on-chip quantum information circuits
Pure cerebellar ataxia due to bi-allelic PRDX3 variants including recurring p.Asp202Asn
Bi-allelic variants in peroxiredoxin 3 (PRDX3) have only recently been associated with autosomal recessive spinocerebellar ataxia characterized by early onset slowly progressive cerebellar ataxia, variably associated with hyperkinetic and hypokinetic features, accompanied by cerebellar atrophy and occasional olivary and brainstem involvement. Herein, we describe a further simplex case carrying a reported PRDX3 variant as well as two additional cases with novel variants. We report the first Brazilian patient with SCAR32, replicating the pathogenic status of a known variant. All presented cases from the Brazilian and Indian populations expand the phenotypic spectrum of the disease by displaying prominent neuroradiological findings. SCAR32, although rare, should be included in the differential diagnosis of sporadic or recessive childhood and adolescent-onset pure and complex cerebellar ataxia
Intellectual property rights related to the genetically modified glyphosate tolerant soybeans in Brazil
Análise de tratamento anti-rábico humano pós-exposição em região da Grande São Paulo, Brasil
Using co-authorship networks to map and analyse global Neglected Tropical Disease research with an affiliation to Germany
Neglected tropical disease research has changed considerably in recent decades, and the German government is committed to addressing its past neglect of NTD research. Our aim was to use an innovative social network analysis of bibliometric data to map neglected tropical disease research networks that are inside of and affiliated with Germany, thereby enabling data-driven health policy decision-making. We created and analysed co-author networks from publications in the SCOPUS database, with a focus on five diseases. We found that Germany's share of global publication output for NTDs is approximately half that of other medical research fields. Furthermore, we identified institutions with prominent NTD research within Germany and strong research collaborations between German institutions and partners abroad, mostly in other high-income countries. This allowed an assessment of strong collaborations for further development, e.g., for research capacity strengthening in low-income-countries, but also for identifying missed opportunities for collaboration within the network. Through co-authorship network analysis of individual researcher networks, we identified strong performers by using classic bibliometric parameters, and we identified academic talent by social network analysis parameters on an individual level
Bony fishes (Teleostei) caught by small-scale fisheries off central to south coast of São Paulo State, Southeastern Brazil
- …