W-algebras from symplectomorphisms

It is shown how $W$-algebras emerge from very peculiar canonical transformations with respect to the canonical symplectic structure on a compact Riemann surface. The action of smooth diffeomorphisms of the cotangent bundle on suitable generating functions is written in the BRS framework while a $W$-symmetry is exhibited. Subsequently, the complex structure of the symmetry spaces is studied and the related BRS properties are discussed. The specific example of the so-called $W_3$-algebra is treated in relation to some other different approaches.Comment: LaTex, 25 pages, no figures, to appear in Journ. Math. Phy

Seesaw model in SO(10) with an upper limit on right-handed neutrino masses

In the framework of SO(10) gauge unification and the seesaw mechanism, we show that the upper bound on the mass of the heaviest right-handed neutrino $M_{R_3} < 3 \times 10^{11}$ GeV, given by the Pati-Salam intermediate scale of $B-L$ spontaneous symmetry breaking, constrains the observables related to the left-handed light neutrino mass matrix. We assume such an upper limit on the masses of right-handed neutrinos and, as a first approximation, a Cabibbo form for the matrix $V^L$ that diagonalizes the Dirac neutrino matrix $m_D$. Using the inverse seesaw formula, we show that our hypotheses imply a triangular relation in the complex plane of the light neutrino masses with the Majorana phases. We obtain normal hierarchy with an absolute scale for the light neutrino spectrum. Two regions are allowed for the lightest neutrino mass $m_1$ and for the Majorana phases, implying predictions for the neutrino mass measured in Tritium decay and for the double beta decay effective mass $||$.Comment: 14 pages. Revised version with 3 figure

Symmetries of topological field theories in the BV-framework

Topological field theories of Schwarz-type generally admit symmetries whose algebra does not close off-shell, e.g. the basic symmetries of BF models or vector supersymmetry of the gauge-fixed action for Chern-Simons theory (this symmetry being at the origin of the perturbative finiteness of the theory). We present a detailed discussion of all these symmetries within the algebraic approach to the Batalin-Vilkovisky formalism. Moreover, we discuss the general algebraic construction of topological models of both Schwarz- and Witten-type.Comment: 30 page

Genome-Wide ENU Mutagenesis in Combination with High Density SNP Analysis and Exome Sequencing Provides Rapid Identification of Novel Mouse Models of Developmental Disease

BACKGROUND Mice harbouring gene mutations that cause phenotypic abnormalities during organogenesis are invaluable tools for linking gene function to normal development and human disorders. To generate mouse models harbouring novel alleles that are involved in organogenesis we conducted a phenotype-driven, genome-wide mutagenesis screen in mice using the mutagen N-ethyl-N-nitrosourea (ENU). METHODOLOGY/PRINCIPAL FINDINGS ENU was injected into male C57BL/6 mice and the mutations transmitted through the germ-line. ENU-induced mutations were bred to homozygosity and G3 embryos screened at embryonic day (E) 13.5 and E18.5 for abnormalities in limb and craniofacial structures, skin, blood, vasculature, lungs, gut, kidneys, ureters and gonads. From 52 pedigrees screened 15 were detected with anomalies in one or more of the structures/organs screened. Using single nucleotide polymorphism (SNP)-based linkage analysis in conjunction with candidate gene or next-generation sequencing (NGS) we identified novel recessive alleles for Fras1, Ift140 and Lig1. CONCLUSIONS/SIGNIFICANCE In this study we have generated mouse models in which the anomalies closely mimic those seen in human disorders. The association between novel mutant alleles and phenotypes will lead to a better understanding of gene function in normal development and establish how their dysfunction causes human anomalies and disease.This work was enabled by the Australian Phenomics Network and partly supported by funding from the Australian Government’s National Collaborative Research Infrastructure Strategy, a Strategic Grant from the Faculty of Medicine, Nursing and Health Sciences at Monash University, and the Victorian Government’s Operational Infrastructure Support Program. IS acknowledges support through the NH&MRC R. Douglas Wright and ARC Future Fellowship schemes. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript

Z boson production in Pb+Pb collisions at √Snn = 5.02 TeV measured by the ATLAS experiment

The production yield of Z bosons is measured in the electron and muon decay channels in Pb+Pb collisions at √S = 5.02 TeV with the ATLAS detector. Data from the 2015 LHC run corresponding to an integrated luminosity of 0.49 nb are used for the analysis. The Z boson yield, normalised by the total number of minimum-bias events and the mean nuclear thickness function, is measured as a function of dilepton rapidity and event centrality. The measurements in Pb+Pb collisions are compared with similar measurements made in proton-proton collisions at the same centre-of-mass energy. The nuclear modification factor is found to be consistent with unity for all centrality intervals. The results are compared with theoretical predictions obtained at next-to-leading order using nucleon and nuclear parton distribution functions. The normalised Z boson yields in Pb+Pb collisions lie 1-3σ above the predictions. The nuclear modification factor measured as a function of rapidity agrees with unity and is consistent with a next-to-leading-order QCD calculation including the isospin effect. nn -

Search for flavour-changing neutral currents in processes with one top quark and a photon using 81 fb−1 of pp collisions at s=13TeV with the ATLAS experiment

A search for flavour-changing neutral current (FCNC) events via the coupling of a top quark, a photon, and an up or charm quark is presented using 81 fb−1 of proton–proton collision data taken at a centre-of-mass energy of 13 TeV with the ATLAS detector at the LHC. Events with a photon, an electron or muon, a b-tagged jet, and missing transverse momentum are selected. A neural network based on kinematic variables differentiates between events from signal and background processes. The data are consistent with the background-only hypothesis, and limits are set on the strength of the tqγ coupling in an effective field theory. These are also interpreted as 95% CL upper limits on the cross section for FCNC tγ production via a left-handed (right-handed) tuγ coupling of 36 fb (78 fb) and on the branching ratio for t→γu of 2.8×10−5 (6.1×10−5). In addition, they are interpreted as 95% CL upper limits on the cross section for FCNC tγ production via a left-handed (right-handed) tcγ coupling of 40 fb (33 fb) and on the branching ratio for t→γc of 22×10−5 (18×10−5)