Veno-venous extracorporeal membrane oxygenation in pregnancy: does foetal viability matter?

With the increasing use of extracorporeal membrane oxygenation for adults with acute hypoxic respiratory failure, the indications for its use have expanded. We wanted to share the results of a recent case from our institution, of a woman who experienced respiratory failure secondary to hyperemesis gravidarum (HG). HG is a rare complication of pregnancy (0.3% to 2.0% of pregnancies), resulting in uncontrolled or excessive nausea and vomiting with dehydration and weight loss, typically in the first to mid second trimester, and is a diagnosis of exclusion

Supernovae as a probe of particle physics and cosmology

It has very recently been demonstrated by Csaki, Kaloper and Terning (CKT) that the faintness of supernovae at high redshift can be accommodated by mixing of a light axion with the photon in the presence of an intergalactic magnetic field, as opposed to the usual explanation of an accelerating universe by a dark energy component. In this paper we analyze further aspects of the CKT mechanism and its generalizations. The CKT mechanism also passes various cosmological constraints from the fluctuations of the CMB and the formation of structure at large scales, without requiring an accelerating phase in the expansion of the Universe. We investigate the statistical significance of current supernova data for pinning down the different components of the cosmological energy-momentum tensor and for probing physics beyond the standard models.Comment: 17 pages, LaTeX, 4 figures; v2: typos corrected, minor changes, references added; v3: updated figures, details regarding fits include

Quantum Limits of Stochastic Cooling of a Bosonic Gas

The quantum limits of stochastic cooling of trapped atoms are studied. The energy subtraction due to the applied feedback is shown to contain an additional noise term due to atom-number fluctuations in the feedback region. This novel effect is shown to dominate the cooling efficiency near the condensation point. Furthermore, we show first results that indicate that Bose--Einstein condensation could be reached via stochastic cooling.Comment: 5 pages, 3 figures, to appear in Phys. Rev.

Synchronization of Hamiltonian motion and dissipative effects in optical lattices: Evidence for a stochastic resonance

We theoretically study the influence of the noise strength on the excitation of the Brillouin propagation modes in a dissipative optical lattice. We show that the excitation has a resonant behavior for a specific amount of noise corresponding to the precise synchronization of the Hamiltonian motion on the optical potential surfaces and the dissipative effects associated with optical pumping in the lattice. This corresponds to the phenomenon of stochastic resonance. Our results are obtained by numerical simulations and correspond to the analysis of microscopic quantities (atomic spatial distributions) as well as macroscopic quantities (enhancement of spatial diffusion and pump-probe spectra). We also present a simple analytical model in excellent agreement with the simulations

Localization by disorder in the infrared conductivity of (Y,Pr)Ba2Cu3O7 films

The ab-plane reflectivity of (Y{1-x}Prx)Ba2Cu3O7 thin films was measured in the 30-30000 cm-1 range for samples with x = 0 (Tc = 90 K), x = 0.4 (Tc = 35 K) and x = 0.5 (Tc = 19 K) as a function of temperature in the normal state. The effective charge density obtained from the integrated spectral weight decreases with increasing x. The variation is consistent with the higher dc resistivity for x = 0.4, but is one order of magnitude smaller than what would be expected for x = 0.5. In the latter sample, the conductivity is dominated at all temperatures by a large localization peak. Its magnitude increases as the temperature decreases. We relate this peak to the dc resistivity enhancement. A simple localization-by-disorder model accounts for the optical conductivity of the x = 0.5 sample.Comment: 7 pages with (4) figures include

A noninvasive hemoglobin monitor in the pediatric intensive care unit

Background Critically ill pediatric patients frequently require hemoglobin monitoring. Accurate noninvasive Hb (SpHb) would allow practitioners to decrease anemia from repeated blood draws, traumatic blood draws, and a decreased number of laboratory Hb (LabHb) medical tests. The Food and Drug Administration has approved the Masimo Pronto SpHb and associated Rainbow probes; however, its use in the pediatric intensive care unit (PICU) is controversial. In this study, we define the degree of agreement between LabHb and SpHb using the Masimo Pronto SpHb Monitor and identify clinical and demographic conditions associated with decreased accuracy. Materials and methods We performed a prospective, observational study in a large PICU at an academic medical center. Fifty-three pediatric patients (30-d and 18-y-old), weighing >3 kg, admitted to the PICU from January-April 2013 were examined. SpHb levels measured at the time of LabHb blood draw were compared and analyzed. Results Only 83 SpHb readings were obtained in 118 attempts (70.3%) and 35 readings provided a result of "unable to obtain." The mean LabHb and SpHb were 11.1 g/dL and 11.2 g/dL, respectively. Bland-Altman analysis showed a mean difference of 0.07 g/dL with a standard deviation of ±2.59 g/dL. Pearson correlation is 0.55, with a 95% confidence interval between 0.38 and 0.68. Logistic regression showed that extreme LabHb values, increasing skin pigmentation, and increasing body mass index were predictors of poor agreement between SpHb and LabHb (P < 0.05). Separately, increasing body mass index, hypoxia, and hypothermia were predictors for undetectable readings (P < 0.05). Conclusions The Masimo Pronto SpHb Monitor provides adequate agreement for the trending of hemoglobin levels in critically ill pediatric patients. However, the degree of agreement is insufficient to be used as the sole indicator for transfusion decisions and should be used in context of other clinical parameters to determine the need for LabHb in critically ill pediatric patients

Lorentz breaking Effective Field Theory and observational tests

Analogue models of gravity have provided an experimentally realizable test field for our ideas on quantum field theory in curved spacetimes but they have also inspired the investigation of possible departures from exact Lorentz invariance at microscopic scales. In this role they have joined, and sometime anticipated, several quantum gravity models characterized by Lorentz breaking phenomenology. A crucial difference between these speculations and other ones associated to quantum gravity scenarios, is the possibility to carry out observational and experimental tests which have nowadays led to a broad range of constraints on departures from Lorentz invariance. We shall review here the effective field theory approach to Lorentz breaking in the matter sector, present the constraints provided by the available observations and finally discuss the implications of the persisting uncertainty on the composition of the ultra high energy cosmic rays for the constraints on the higher order, analogue gravity inspired, Lorentz violations.Comment: 47 pages, 4 figures. Lecture Notes for the IX SIGRAV School on "Analogue Gravity", Como (Italy), May 2011. V.3. Typo corrected, references adde