134 research outputs found
Separation of Flip and Non-Flip parst of Charge Exchange np->pn at energies Tn = 0.5 - 2.0 GeV
The new Delta-Sigma experimental data on the ratio allowed
separating the Flip and Non-Flip parts of the differential cross section of
charge exchange process at the zero angle by the Dean formula. The
PSA solutions for the elastic scattering are transformed to the
charge exchange representation using unitary transition, and good
agreement is obtain.Comment: 7 pages, 2 figure
Recommended from our members
DNA dioxygenases Tet2/3 regulate gene promoter accessibility and chromatin topology in lineage-specific loci to control epithelial differentiation
YesExecution of lineage-specific differentiation programs requires tight coordination between many regulators including Ten-eleven translocation (TET) family enzymes, catalyzing 5-methylcytosine oxidation in DNA. Here, by using Keratin 14–Cre–driven ablation of Tet genes in skin epithelial cells, we demonstrate that ablation of Tet2/Tet3 results in marked alterations of hair shape and length followed by hair loss. We show that, through DNA demethylation, Tet2/Tet3 control chromatin accessibility and Dlx3 binding and promoter activity of the Krt25 and Krt28 genes regulating hair shape, as well as regulate interactions between the Krt28 gene promoter and distal enhancer. Moreover, Tet2/Tet3 also control three-dimensional chromatin topology in Keratin type I/II gene loci via DNA methylation–independent mechanisms. These data demonstrate the essential roles for Tet2/3 in establishment of lineage-specific gene expression program and control of Dlx3/Krt25/Krt28 axis in hair follicle epithelial cells and implicate modulation of DNA methylation as a novel approach for hair growth control.This work was supported by the National Institutes of Health grant 5R01 AR075776 (V.A.B. and A.A.S.) and grant 5R01 AR071727 (V.A.B. and A.A.S.) and the National Science Foundation of China (G.-L.X.).Research Development Fund Publication Prize Award winner, Dec 2022
Panspermia, Past and Present: Astrophysical and Biophysical Conditions for the Dissemination of Life in Space
Astronomically, there are viable mechanisms for distributing organic material
throughout the Milky Way. Biologically, the destructive effects of ultraviolet
light and cosmic rays means that the majority of organisms arrive broken and
dead on a new world. The likelihood of conventional forms of panspermia must
therefore be considered low. However, the information content of dam-aged
biological molecules might serve to seed new life (necropanspermia).Comment: Accepted for publication in Space Science Review
The H states studied in the reaction and evidence of extremely correlated character of the H ground state
The extremely neutron-rich system H was studied in the direct
H transfer reaction with a 26
MeV secondary He beam. The measured missing mass spectrum shows a
resonant state in H at MeV relative to the H+ threshold.
The population cross section of the presumably -wave states in the energy
range from 4 to 8 MeV is
b/sr in the angular range . The
obtained missing mass spectrum is free of the H events below 3.5 MeV
( b/sr in the same angular
range). The steep rise of the H missing mass spectrum at 3 MeV allows to
show that MeV is the lower limit for the possible resonant state
energy in H tolerated by our data. According to paring energy estimates,
such a MeV resonance is a realistic candidate for the H ground
state (g.s.). The obtained results confirm that the decay mechanism of the
H g.s.\ (located at 2.2 MeV above the H+ threshold) is the
``true'' (or simultaneous) emission. The resonance energy profiles and the
momentum distributions of the sequential H \,\rightarrow \,
^5H(g.s.)+n\, \rightarrow \, ^3H+ decay fragments were analyzed by the
theoretically-updated direct four-body-decay and sequential-emission
mechanisms. The measured momentum distributions of the H fragments in the
H rest frame indicate very strong ``dineutron-type'' correlations in the
H ground state decay.Comment: 9 pages, 11 figure
- …