18 research outputs found

    POLISH TOWNS AND THE CHANGES IN THEIR AREAS AND POPULATION DENSITIES

    Get PDF
    DOI: 10.2478 Available on-line at: http://www.bulletinofgeography.umk.pl http://versita.com/bgssThis article presents the spatial and population density changes in Polish towns in the years 1960–2003. The assumed time frame allowed identifying area changes for a complete set of towns in different socio-economic conditions: the period of intense industrialisation, the economic crisis of the 1980s, the period of economic transition and finally in the years of a market economy. The investigation revealed that the trend shown by changes and the size of a town as measured by the number of its population are distinctly interrelated. It also demonstrated a much stronger dynamics of changes in the first subperiod, i.e. years 1960–1985, followed by a phase of relative stabilization (compared with the previous period) after the year 1980 (mainly of the spatial changes). Moreover, change intensity and change trends observed for the urban areas and population densities vary considerably in terms of space

    Home enteral nutrition in children—2010 nationwide survey of the polish society for clinical nutrition of children

    Get PDF
    Published epidemiologic data on the administration rates of enteral/parenteral home nutrition is very limited. The aim of this first nationwide study was to assess the availability of pediatric home enteral nutrition (HEN) services in Poland. The questionnaire was sent to all regional centers providing pediatric HEN services in Poland (n = 14). The analysis included the number of pediatric patients who received HEN in 2010, their demographic characteristics and geographical distribution. Furthermore, the distributions of indications and methods of enteral nutrition administration were analyzed, along with the reasons of withdrawal from the HEN program. The number and fraction of children receiving HEN increased in 2010, from 433 (11.34 per 1 million inhabitants) on January 1st to 525 (13.75) on December 31st. Marked differences were observed in geographical distribution of this parameter, from zero to up to 30 pediatric patients per 1 million inhabitants. Median age of patients was 6 years (range: 9 months–18 years). In most cases, HEN was prescribed due to neurological disorders (n = 337, 64.2%), and administered by means of gastrostomy (n = 450, 85.71%). This study revealed the dynamic development of pediatric HEN services in Poland but also documented their potential regional shortages

    Potentiation of the anti-tumour effects of Photofrin®-based photodynamic therapy by localized treatment with G-CSF

    Get PDF
    Photofrin®-based photodynamic therapy (PDT) has recently been approved for palliative and curative purposes in cancer patients. It has been demonstrated that neutrophils are indispensable for its anti-tumour effectiveness. We decided to evaluate the extent of the anti-tumour effectiveness of PDT combined with administration of granulocyte colony-stimulating factor (G-CSF) as well as the influence of Photofrin®and G-CSF on the myelopoiesis and functional activity of neutrophils in mice. An intensive treatment with G-CSF significantly potentiated anti-tumour effectiveness of Photofrin®-based PDT resulting in a reduction of tumour growth and prolongation of the survival time of mice bearing two different tumours: colon-26 and Lewis lung carcinoma. Moreover, 33% of C-26-bearing mice were completely cured of their tumours after combined therapy and developed a specific and long-lasting immunity. The tumours treated with both agents contained more infiltrating neutrophils and apoptotic cells then tumours treated with either G-CSF or PDT only. Importantly, simultaneous administration of Photofrin®and G-CSF stimulated bone marrow and spleen myelopoiesis that resulted in an increased number of neutrophils demonstrating functional characteristics of activation. Potentiated anti-tumour effects of Photofrin®-based PDT combined with G-CSF observed in two murine tumour models suggest that clinical trials using this tumour therapy protocol would be worth pursuing. © 2000 Cancer Research Campaig

    <sup>222</sup>Rn release rate from groundwater to the atmosphere

    No full text
    The authors conducted studies on the release rate of 222Rn from groundwater flowing out of a spring, from metamorphic reservoir rocks. This source gives rise to a stream about 205 m long. The activity concentration of Rn in the spring was about 700 Bq/dm33, took place at a distance of about 1 70-180 metres from the spring. With regard to the waterflow path, flowtime and the volume of water flowing through the cross-section of the tested stream, the exhalation coefficient of 222Rn from water to atmospheric air is 3.80 Bq/dm3/m, 1.51 Bq/dm3/s and 1. 25 Bq/dm3/dm3, respctively. According to the authors, further research conducted in other springs occurring in other types of rocks and under different flow conditions (at different times of the year) will allow characterizing the dynamics of the process of 222Rn release from groundwater through surface waters into the atmosphere. Perhaps this process can be described with a universal mathematical function

    Comparative analysis of the Baszkówka and Mt. Tazerzait chondrites: genetic conclusions based on astrophysical data and the mineralogical and petrological data

    No full text
    The L5 chondrites Baszkówka and Mt. Tazerzait are characterised. Their astronomical, mineralogical and petrological characteristics confirm that these meteorites are similar. They could be derived from the same parent body, though from the different depths below its surface. A third meteorite - the Tjerebon - might have arisen from the same swarm of meteoroids. The parent body to these meteorites in the asteroid belt can not be established at present. The porosity, of these chondrites suggests that they formed close to the surface of their parent asteroid. The process of formation of the parent rock of the Baszkówka chondrite is similar in some respects to sedimentation of a weakly compacted terrestrial sandstone. Thus, a two-stage geological history may be envisaged: firstly formation of the component minerals and mineral aggregates of this meteorite. Then, later in a different environment, the accretion of fragments of this parent material, together with a small amount of matrix, into a strongly porous sedimentary rock

    What is at risk? – an environmental health risk assessment related with pharmaceutical substances in drinking water

    No full text
    Constantly increasing rate of drugs’ consumption can be related with environmental abundance of drug substances and their degradation products. Unused and used drugs are often discharged into municipal wastewaters or landfills. Wastewater treatment plants are not able to remove the entire load of drugs. Especially those which occur occasionally or at very low concentrations. Therefore, a variety of pharmaceuticals occur in surface and drinking water sources. A chronic low-level exposure to drugs occurring in a water environment can cause: antibiotic resistance, allergic reactions (eg. Penicillin), cause carcinogenesis (oxytetracycline, furazolidone), nephropathy (gentamicin) and have a negative impact on the natural human intestinal microflora. Therefore, it is not an easy task to assess a common human health effects related with chronic exposure to low doses of active pharmaceutical substances. Nonetheless, such knowledge seems essential in order to undertake preventive actions that would substantially decrease the level of health risk
    corecore