DETERMINATION OF PHENYLEPHRINE HYDROCHLORIDE IN PHARMACEUTICAL PREPARATIONS USING SPECTROPHOTOMETRIC METHOD

Objective: A simple and sensitive spectrophotometric method has been presented for the determination of phenylephrine hydrochloride by coupling reaction with diazotized sulfacetamide sodium. Methods: The method is based on the diazotization reaction of sulfacetamide sodium with sodium nitrite in the presence of hydrochloric acid to form diazonium salt, which is coupled with the drug in alkaline medium to form azo dye, showing absorption maxima at 425 nm. Results: Calibration plot was linear over the concentration range of 2–24 μg/mL and detection limit of 0.278 μg/mL with a correlation coefficient of 0.9929. All different chemical and physical experimental parameters affecting on the development and stability of the colored product were carefully studied. Conclusions: The proposed method was successfully applied to the determination of phenylephrine in nasal drops with good precision and sensitivity

Generalized *⊕Z* Supplemented Modules and Generalized*⊕ Co-finitely Supplemented Modules

Let R be a commutative ring with identity, an R-module M is called G*⊕ Z* supplemented modules, if every sub module containing Z*(M) has generalized* supplement in M that is a direct summand of M . and an R-module M is called generalized*co-finitely supplemented, if every co-finite has sub module of M has a generalized* supplement in M. and M is called ⊕ co- finitely generalized* supplemented , if every co- finite sub module of M has G*S that is direct summand of M

Observation of sub-natural linewidths for cold atoms in a magneto-optic trap

We have studied the absorption of a weak probe beam through cold rubidium atoms in a magneto-optic trap. The absorption spectrum shows two peaks with the smaller peak having linewidth as small as 28% of the natural linewidth. The modification happens because the laser beams used for trapping also drive the atoms coherently between the ground and excited states. This creates ``dressed'' states whose energies are shifted depending on the strength of the drive. Linewidth narrowing occurs due to quantum coherence between the dressed states. The separation of the states increases with laser intensity and detuning, as expected from this model.Comment: 8 pages, 4 figure

Evaluation of the Organic-Pollution Based on the Determination of some Polycyclic Aromatic Hydrocarbons(PAHs) in Tigris River Water in 2012 at Baghdad City , Iraq

This study aims to predict the organic pollution produced from the presence of some polycyclic aromatic hydrocarbons (PAHs) and determination it's concentrations (µg/L , ppb) in Tigris river water by a collection twenty-seven water samples from a selected three stations with nine sampling sites and three depths of water (5 cm , 2 m and 4 m) each site for 4.6 km distance of a geographic studied area which is located between the ( Al-Senak and AL-Sarrafiah bridges ) at Baghdad city – Iraq on May, 2012. The geographic location was determined with a Global Positioning System (GPS) and Geographic Information System (GIS) software program. The concentrations of fourteen components (PAHs) were performed using the reverse phase of high performance liquid chromatography (RP-HPLC) technique. Samples were chemically treated using liquid-liquid extraction method , filtered , extracted , dried , evaporated and pre-concentrated in order to be ready for analysis . The determined concentrations of (PAHs) for the studied area did exceed the criteria values proposed by the International Environmental Organizations like American Environment Protection Agency (U.S-EPA) and British Health Agency (BHA) . The results were showed that the maximum values of the total concentrations (PAHs) were found to be 228 µg/L (5 cm depth , site F, Medicine city station , Al-Resafa bank) , 192.1 µg/L (2 m depth , site D , Medicine city station , Al-Karkh bank) and 80.1 µg/L (4 m depth , site D , Medicine city station , Al-Karkh bank) , while the minimum values were found to be be 51.2 µg/L (5 cm depth , site I, Al-Sarrafia bridge station , Al-Resafa bank) , 33.4 µg/L (2 m depth , site G , Al-Sarrafia bridge station , Al-Karkh bank) and 4.8 µg/L (4 m depth , site G , Al-Sarrafia bridge station , Al-Karkh bank)

Synthesis and Characterization of New Benzothiazole-derived Schiff Bases Metal Complexes

تضمنت الدراسة تحضير معقدات جديده غير متجانسة الحلقة. تشمل هذه المركبات مشتق -2امینو 3, 1 بنزوثایازول المعوض 1 (4-كلورو-6-اوكسيد النتروز-2امینو 3, 1- بنزوثایازول (من 2-كلورو-4-اوكسيد نتروزالانیلین)) كمادة اولية ومفاعلته مع ثلاث الدیھایدات اروماتیة مختلفة بوجود الكحول المثيلي لتحضير قواعد شف ثلاثية السن 4-2. ثم مفاعلة مركبات البنزوثایازول ومشتقاته مع ايونات البوتاسيوم (I)والنيكل (II) والالمنيوم (III) لتكوين المعقدات المخلبيه7-5 (c-a). تم تشخيص تراكيب المعقدات الجديدة المحضرة بواسطة قياس درجه الانصهار، اطياف الاشعة تحت الحمراء والبعض منهم بواسطة الرنين النووي المغناطيسي البروتوني وحيود الأشعة السينية ومن نتائج الاطياف تم اقتراح شكل البنية الأساسية للمعقدات. نتوقع من هذا العمل ان يكون له اهميه في تصنيع وتطوير مواد علاجيه.Nitrogen-comprising heterocyclic compounds and their derivatives have empirically been invaluable as therapeutic agents. Fundamentally, 4-chloro-6-nitro-2-amino-1,3-benzothiazole 1 was synthesized via bromination of 2-chloro-4-nitro aniline with ammonium thiocyanate. This new heterocyclic haloorganoamino-1,3-benzothiazole derivative, was a starting material, which condensed and tethered with three different aromatic aldehyde pendant arm in presence of ethanol and glacial acetic acid isolating an interesting sequence of tridentate Schiff bases 2-4. These compounds were used for complexation reactions in 1:1 (metal: ligand) stoichiometry to obtain heteroleptic Al(III), Ni (II) and K(I) benzothiazole chelates 5-7(a-c) of the type [Al(L)Cl2, Ni(L)Cl, K(L) {L = Schiff base derivatives}]. The newly synthesized complexes were characterized by the melting points, IR and some of them by 1H-NMR spectroscopy and only one by X-ray techniques. The structures of complexes were anticipated from the spectroscopic studies

Field-programmable gate array design of image encryption and decryption using Chua’s chaotic masking

This article presents a simple and efficient masking technique based on Chua chaotic system synchronization. It includes feeding the masked signal back to the master system and using it to drive the slave system for synchronization purposes. The proposed system is implemented in a field programmable gate array (FPGA) device using the Xilinx system generator tool. To achieve synchronization, the Pecora-Carroll identical cascading synchronization approach was used. The transmitted signal should be mixed or masked with a chaotic carrier and can be processed by the receiver without any distortion or loss. For different images, the security analysis is performed using the histogram, correlation coefficient, and entropy. In addition, FPGA hardware co-simulation based Xilinx Artix7 xc7a100t-1csg324 was used to check the reality of the encryption and decryption of the images

Batch and Flow-Injection Spectrophotometric Determination of Procaine HCl in Pharmaceutical Preparations Via Using Diazotization and Coupling Reaction

Simple and sensitive batch and Flow-injection spectrophotometric methods for the determination of Procaine HCl in pure form and in injections were proposed. These methods were based on a diazotization reaction of procaine HCl with sodium nitrite and hydrochloric acid to form diazonium salt, which is coupled with chromatropic acid in alkaline medium to form an intense pink water-soluble dye that is stable and has a maximum absorption at 508 nm. A graphs of absorbance versus concentration show that Beer’s law is obeyed over the concentration range of 1-40 and 5-400 µg.ml-1 of Procaine HCl, with detection limits of 0.874 and 3.75 µg.ml-1 of Procaine HCl for batch and FIA methods respectively. The FIA average sample throughput was 70 h-1. All different chemical and physical experimental parameters that affecting on the development and stability of the colored product were carefully studied and the proposed methods were applied satisfactorily for the determination of Procaine HCl in an injections samples using the standard addition method