Event-driven management algorithm of an Engineering documents circulation system

Development methodology of an engineering documents circulation system in the design company is reviewed. Discrete event-driven automatic models using description algorithms of project management is offered. Petri net use for dynamic design of projects is offered

Определение отношения 8-оксо-2'-дезоксигуанозина к 2'-дезоксигуанозину в ДНК с помощью обращенно-фазовой ВЭЖХ в сочетании с амперометрической детекцией

The article presents an optimized method for the determination of the ratio of 8-oxo-2'-deoxyguanosine (formed in DNA due to the action of active forms of oxygen) to 2'-deoxyguanosine. The ratio was determined by reverse phase HPLC combined with amperometric detection. It was shown that the ratio increases upon oxidative stress caused by the action of large doses of ascorbic acid in samples of DNA isolated from the liver of experimental rats.В работе проведена оптимизация метода определения отношения 8-оксо-2'-дезоксигуанозина, образующегося в ДНК в результате действия активных форм кислорода, к 2'-дезоксигуанозину методом обращенно-фазовой ВЭЖХ в сочетании с амперометрической детекцией. Показано увеличение этого отношения при окислительном стрессе, вызванном действием больших доз аскорбиновой кислоты, в образцах ДНК, выделенных из печени экспериментальных крыс

Анализ содержания 8-оксо-2'-дезоксигуанозина в ДНК клеток мозга крыс при изучении защитного действия кортексина

The protective effect of cortexin was investigated with the use of acoustic stress hemorrhagic stroke model. A significant decrease of 8-oxo-2'-deoxyguanosine to 2'-deoxyguanosine ratio in the DNA molecule was shown using brain slices of cortexin treated Krushinsky-Molodkina rats.В работе изучено влияние защитного действия препарата кортексин на мозг крыс линии Крушинского-Молодкиной в условиях экспериментального геморрагического инсульта, вызван-ного акустическим стрессом. Показано значительное уменьшение отношения 8-оксо-2'-дезокси-гуанозина к 2'-дезоксигуанозину в ДНК клеток мозга крыс при применении кортексина

MATHEMATICAL PROGRAMS MODERNIZATION BASED ON RUSSIAN AND INTERNATIONAL STANDARDS

Russian education standards have come a long way from being extremely detailed and regulating the content of education programs at all levels to the current state when there is a great freedom for universities in defining its education programs. The downside of that freedom is too general formulations of these competences and absence of framework requirements for the scope and content of individual parts of educational programs for the various types of training. This raises the problem of preserving the unity of educational space in Russia and the traditionally high level of teaching mathematics in Russian universities. Russian scientific and educational community together with industry and business are currently looking for the ways to solve this problem. In the paper, the experience of the modernization educational programs in the field of information and communication technologies is considered. The methodology of creation of valid assessment tools funds to check formation of competences is presented. The presented results are based on the methodology of international and Russian scientific and methodological projects. Currently obtained results of approbation of the methodology showed that the chosen modernization methods are an effective tool for solving the designated math-related problems in engineering education in Russian universities and, consequently, students will start to correspond more adequately to the labor market needs

The experience of updating the educational standards of higher education in the field of ICT

The article describes the experience of Russian universities in integrating professional and educational standards in the design of higher education educational programs in the field of information and communication technologies. A number of aspects of the current versions of FSES have been identified, which pose a problem for interfacing with professional standards in the development of basic educational programs. Methodical recommendations on the actualization of the FSES and the selection of professional standards developed by the leading Russian universities as a result of the implementation of international and domestic projects are presented. The analysis of the conformity of generalized labor functions and their components from professional standards to general professional and professional competences from FSES under the bachelor's program 02.03.02 Fundamental informatics and information technologies is carred out

8-Oxo-7,8-dihydro-2′-deoxyguanosine values measured in brain DNA of rats upon investigating cortexin protective action

The protective effect of cortexin was investigated with the use of acoustic stress hemorrhagic stroke model. A significant decrease of 8-oxo-2'-deoxyguanosine to 2'-deoxyguanosine ratio in the DNA molecule was shown using brain slices of cortexin treated Krushinsky-Molodkina rats