129 research outputs found

    Sustainment of High-Beta Mirror Plasma by Neutral Beams

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    The report presents two experiments carried out in Budker Institute for obtaining the maximum plasma beta (ratio of the plasma pressure to magnetic field pressure) in axially symmetric magnetic field. The experiments are based on injection of powerful focused neutral beams with high neutral power density in the plasma. The produced fast ion population significantly increases the plasma pressure. It the axially symmetric GDT experiment (Gas Dynamic Trap) the plasma beta exceeded 0.6 at the fast ion turning points. The CAT experiment (Compact Axisymmetric Toroid) is being prepared for obtaining a plasmoid with extremely high diamagnetism in axially symmetric magnetic field. Reversal of magnetic field in the plasmoid is possible in this experiment

    The investigation of absolute proper motions of the XPM Catalogue

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    The XPM-1.0 is the regular version of the XPM catalogue. In comparison with XPM the astrometric catalogue of about 280 millions stars covering entire sky from -90 to +90 degrees in declination and in the magnitude range 10^m<B<22^m is something improved. The general procedure steps were followed as for XPM, but some of them are now performed on a more sophisticated level. The XPM-1.0 catalogue contains star positions, proper motions, 2MASS and USNO photometry of about 280 millions of the sources. We present some investigations of the absolute proper motions of XPM-1.0 catalogue and also the important information for the users of the catalogue. Unlike previous version, the XPM-1.0 contains the proper motions over the whole sky without gaps. In the fields, which cover the zone of avoidance or which contain less than of 25 galaxies a quasi absolute calibration was performed. The proper motion errors are varying from 3 to 10 mas/yr, depending on a specific field. The zero-point of the absolute proper motion frame (the absolute calibration) was specified with more than 1 million galaxies from 2MASS and USNO-A2.0. The mean formal error of absolute calibration is less than 1 mas/yr.Comment: 11 pages, 9 figures, accepte

    The managerial mechanism of future competitive technical specialists vocational training: The Russian experience

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    Β© 2016, Econjournals. All rights reserved.The relevance of the paper is reasoned by the search for adequate mechanisms to manage vocational training of future competitive technical specialists. Modern economies demand the training of technical specialists’ new generation ready to project and engineering, production and technological, organizational and management, science and research, service and operational professional activities, as well as the fulfillment of skilled work using modern equipment for the developed technological process. One of the variants of the organization of vocational training of future competitive technical specialists is based on the integration of educational curricula of different levels (primary, secondary and high). The purpose of the paper is to develop a managerial mechanism for future competitive technical specialists’ training based on the integration of educational curricula at different levels (primary, secondary and high). The leading method is the method of action research, allowing obtain new knowledge on the managerial mechanism for vocational training of specialists, capable of a certain type of practical activities, self-organization and competitiveness on the labor market through the integration of primary, secondary and high levels of educational curricula. The article defines the essence of integrated educational curricula of primary, secondary and high levels of vocational training; it justifies the organization of control and assessment procedures of students’ vocational training through the integration of educational curricula at different levels; proposes an algorithm of students’ selection to study on integrated educational curricula. Paper Submissions can be useful for research and teaching staff of technical specialists’ vocational training system, experts of training and retraining centers in the training content’s selection and structuring of research universities’ scientific and pedagogical staff development

    Innovative entrepreneurship in education: A new look in the students training content and existing problems

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    Β© 2016, Econjournals. All rights reserved.This article is aimed at scientific and methodological justification of students’ training content to innovative entrepreneurship. The leading method in the study of this problem is the analysis of students’ innovative entrepreneurship learning experience in Russian universities, which reveals the predominance of the traditional approach in the content of students’ training, as well as unwillingness of the teaching staff and students to innovate. The article identified the necessary competences in the field of innovative entrepreneurship (professional, business, functional, social and communicative), as well as entrepreneurial qualities (integrity, credibility, intelligence, presence of imagination, ability to make decision, ability to organize control, to provide justification of decisions); the methodology of students’ gradual of entrepreneurial competences is developed; factors blocking the effectiveness of the students’ entrepreneurial competences’ formation are revealed

    Morphological changes of the gastric mucosa in patients with duodenogasric reflux: relationship with acidity and helicobacter pylori

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    Purpose: to reveal the peculiarities of the duodenogastric reflux (DGR) impact on acidity and morphological features of the gastric mucosa in patients with "primary" reflux gastritis, as well as in cases of reflux gastritis in combination with H. pylori. Methods: 66 patients with chronic reflux gastritis were examined, 15 people formed a control group. All patients had gastric endoscopy with determination of the gastric acidity and concentration of bile acids. Biopsy material for histological examination was obtained from 55 patients, in 12 cases of suspected intestinal metaplasia additional histochemical (PAS and alcian blue) and immunohistochemical (cytokeratin 20, Villin, carcinoembriogenic antigen, MUC2, CD45) assays were performed. Results: the level of acidity in patients with DGR was higher (pH = 3.55 Β± 2.3) compared to the control group (pH = 6.85 Β± 1.34). Cases of DGR differed from the control group regarding the mononuclear infiltration (p=0,001), foveolar hyperplasia (p=0,001) in both antral and fundic parts of the stomach, mucosal edema (p=0,022) and atrophy (p=0,02) at the level of the antrum, and intestinal metaplasia (p=0,022) at the level of the body. In the presence of H. pylori infection, in addition to the abovementioned signs, infiltration by cells of acute inflammation (p = 0.005) was detected, which indicates an increase in the damaging effect of H. pylori infection in DGR. Conclusion: DGR may lead to "oxidation" of gastric contents. The effect of DGR leads to intestinal metaplasia of the body and atrophy of the antral part of stomach, chronic inflammation and foveolar hyperplasia. The presence of H. pylori boosts the morphological changes in the gastric mucosa caused by DGR.ЦСль: Π²Ρ‹ΡΠ²ΠΈΡ‚ΡŒ Ρ…Π°Ρ€Π°ΠΊΡ‚Π΅Ρ€ воздСйствия Π΄ΡƒΠΎΠ΄Π΅Π½ΠΎΠ³Π°ΡΡ‚Ρ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ Ρ€Π΅Ρ„Π»ΡŽΠΊΡΠ° (Π”Π“Π ) Π½Π° морфологичСскиС ΠΏΠΎΠΊΠ°Π·Π°Ρ‚Π΅Π»ΠΈ слизистой ΠΎΠ±ΠΎΠ»ΠΎΡ‡ΠΊΠΈ ΠΆΠ΅Π»ΡƒΠ΄ΠΊΠ° ΠΏΡ€ΠΈ Β«ΠΏΠ΅Ρ€Π²ΠΈΡ‡Π½ΠΎΠΌΒ» Ρ€Π΅Ρ„Π»ΡŽΠΊΡ-гастритС, Π² Ρ‚ΠΎΠΌ числС, Π² сочСтании с H.pylori, ΠΈΡΡΠ»Π΅Π΄ΠΎΠ²Π°Ρ‚ΡŒ связь Π”Π“Π  с ΡƒΡ€ΠΎΠ²Π½Π΅ΠΌ кислотности. ΠœΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Ρ‹ ΠΈ ΠΌΠ΅Ρ‚ΠΎΠ΄Ρ‹: обслСдовано 66 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Ρ€Π΅Ρ„Π»ΡŽΠΊΡ-гастритом, 15 Ρ‡Π΅Π»ΠΎΠ²Π΅ΠΊ составили Π³Ρ€ΡƒΠΏΠΏΡƒ контроля. ВсСм ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½Π° эзофагогастродуодСноскопия с ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ΠΌ кислотности ΠΈ ΠΊΠΎΠ½Ρ†Π΅Π½Ρ‚Ρ€Π°Ρ†ΠΈΠΈ ΠΆΠ΅Π»Ρ‡Π½Ρ‹Ρ… кислот Π² ΠΆΠ΅Π»ΡƒΠ΄ΠΎΡ‡Π½ΠΎΠΌ содСрТимом. 55 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΎ гистологичСскоС обслСдованиС биопсийного ΠΌΠ°Ρ‚Π΅Ρ€ΠΈΠ°Π»Π° слизистой ΠΎΠ±ΠΎΠ»ΠΎΡ‡ΠΊΠΈ ΠΆΠ΅Π»ΡƒΠ΄ΠΊΠ°, ΠΏΡ€ΠΈ Π½Π°Π»ΠΈΡ‡ΠΈΠΈ ΠΏΡ€ΠΈΠ·Π½Π°ΠΊΠΎΠ² ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΎΠΉ ΠΌΠ΅Ρ‚Π°ΠΏΠ»Π°Π·ΠΈΠΈ 12 ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚Π°ΠΌ ΠΏΡ€ΠΎΠ²Π΅Π΄Π΅Π½ΠΎ Π΄ΠΎΠΏΠΎΠ»Π½ΠΈΡ‚Π΅Π»ΡŒΠ½ΠΎΠ΅ гистохимичСскоС (окраска Π¨ΠΈΡ„Ρ„-ΠΉΠΎΠ΄Π½ΠΎΠΉ кислотой ΠΈ Π°Π»ΡŒΡ†ΠΈΠ°Π½ΠΎΠ²Ρ‹ΠΌ синим) ΠΈ иммуногистохимичСскоС (ΠΎΠΏΡ€Π΅Π΄Π΅Π»Π΅Π½ΠΈΠ΅ экспрСссии Ρ†ΠΈΡ‚ΠΎΠΊΠ΅Ρ€Π°Ρ‚ΠΈΠ½Π° 20, Π²ΠΈΠ»Π»ΠΈΠ½Π°, MUC2, Ρ€Π°ΠΊΠΎΠ²ΠΎΠ³ΠΎ ΡΠΌΠ±Ρ€ΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ Π°Π½Ρ‚ΠΈΠ³Π΅Π½Π°, CD45) исслСдованиС. Ρ€Π΅Π·ΡƒΠ»ΡŒΡ‚Π°Ρ‚Ρ‹: Π£Ρ€ΠΎΠ²Π΅Π½ΡŒ кислотности Ρƒ ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² с Π”Π“Π  Π±Ρ‹Π» Π²Ρ‹ΡˆΠ΅ (рН=3,55Β±2,3) ΠΏΠΎ ΡΡ€Π°Π²Π½Π΅Π½ΠΈΡŽ с Π³Ρ€ΡƒΠΏΠΏΠΎΠΉ контроля (рН=6,85Β±1,34). Из морфологичСских ΠΏΡ€ΠΈΠ·Π½Π°ΠΊΠΎΠ² ΠΏΡ€ΠΈ Π΄Π“Ρ€ Π·Π½Π°Ρ‡ΠΈΠΌΠΎ ΠΎΡ‚Π»ΠΈΡ‡Π°Π»ΠΈΡΡŒ ΠΎΡ‚ Π³Ρ€ΡƒΠΏΠΏΡ‹ контроля мононуклСарная ΠΈΠ½Ρ„ΠΈΠ»ΡŒΡ‚Ρ€Π°Ρ†ΠΈΡ (Ρ€=0,001), фовСолярная гипСрплазия (Ρ€=0,001) Π² ΠΎΠ±ΠΎΠΈΡ… ΠΎΡ‚Π΄Π΅Π»Π°Ρ… ΠΆΠ΅Π»ΡƒΠ΄ΠΊΠ°, ΠΎΡ‚Π΅ΠΊ (Ρ€=0,022) ΠΈ атрофия (Ρ€=0,02) Π°Π½Ρ‚Ρ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ ΠΎΡ‚Π΄Π΅Π»Π°, ΠΊΠΈΡˆΠ΅Ρ‡Π½Π°Ρ мСтаплазия (Ρ€=0,022) Π½Π° ΡƒΡ€ΠΎΠ²Π½Π΅ Ρ‚Π΅Π»Π° ΠΆΠ΅Π»ΡƒΠ΄ΠΊΠ°. ΠŸΡ€ΠΈ Π½Π°Π»ΠΈΡ‡ΠΈΠΈ ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ H. pylori, ΠΏΠΎΠΌΠΈΠΌΠΎ ΡƒΠΆΠ΅ выявлСнных ΠΏΡ€ΠΈΠ·Π½Π°ΠΊΠΎΠ², выявляСтся ΠΈΠ½Ρ„ΠΈΠ»ΡŒΡ‚Ρ€Π°Ρ†ΠΈΡ ΠΊΠ»Π΅Ρ‚ΠΊΠ°ΠΌΠΈ острого воспалСния (Ρ€=0,005), Ρ‡Ρ‚ΠΎ ΡΠ²ΠΈΠ΄Π΅Ρ‚Π΅Π»ΡŒΡΡ‚Π²ΡƒΠ΅Ρ‚ ΠΎΠ± усилСнии ΠΏΠΎΠ²Ρ€Π΅ΠΆΠ΄Π°ΡŽΡ‰Π΅Π³ΠΎ дСйствия ΠΈΠ½Ρ„Π΅ΠΊΡ†ΠΈΠΈ H. pylori ΠΏΡ€ΠΈ Π”Π“Π . Π’Ρ‹Π²ΠΎΠ΄Ρ‹: ВоздСйствиС Π”Π“Π  ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΊ «окислСнию» ΠΆΠ΅Π»ΡƒΠ΄ΠΎΡ‡Π½ΠΎΠ³ΠΎ содСрТимого. ВоздСйствиС Π”Π“Π  ΠΏΡ€ΠΈΠ²ΠΎΠ΄ΠΈΡ‚ ΠΊ ΠΊΠΈΡˆΠ΅Ρ‡Π½ΠΎΠΉ ΠΌΠ΅Ρ‚Π°ΠΏΠ»Π°Π·ΠΈΠΈ Ρ‚Π΅Π»Π° ΠΈ Π°Ρ‚Ρ€ΠΎΡ„ΠΈΠΈ Π°Π½Ρ‚Ρ€Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ ΠΎΡ‚Π΄Π΅Π»Π° ΠΆΠ΅Π»ΡƒΠ΄ΠΊΠ° Π½Π° Ρ„ΠΎΠ½Π΅ хроничСского воспалСния ΠΈ фовСолярной Π³ΠΈΠΏΠ΅Ρ€ΠΏΠ»Π°Π·ΠΈΠΈ. ΠŸΡ€ΠΈΡΡƒΡ‚ΡΡ‚Π²ΠΈΠ΅ H. pylori усиливаСт Π²Ρ‹Π·Π²Π°Π½Π½Ρ‹Π΅ Π”Π“Π  морфологичСскиС измСнСния слизистой ΠΎΠ±ΠΎΠ»ΠΎΡ‡ΠΊΠΈ ΠΆΠ΅Π»ΡƒΠ΄ΠΊΠ°

    ИсслСдованиС тСрапСвтичСской эффСктивности Ρ‚Ρ€ΠΎΠ²Π΅Π½Ρ‚ΠΎΠ»Π° Ρƒ Π±ΠΎΠ»ΡŒΠ½Ρ‹Ρ… Π±Ρ€ΠΎΠ½Ρ…ΠΈΠ°Π»ΡŒΠ½ΠΎΠΉ астмой ΠΈ хроничСской обструктивной болСзнью Π»Π΅Π³ΠΊΠΈΡ… ΠΏΡ€ΠΎΡ„Π΅ΡΡΠΈΠΎΠ½Π°Π»ΡŒΠ½ΠΎΠ³ΠΎ Π³Π΅Π½Π΅Π·Π°

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    Respiratory pathology takes 15 to 35 % of occupational diseases and a half of them falls to chronic obstructive pulmonary disease (COPD) and asthma. The aim of this study was to evaluate clinical efficiency and safety of troventol in workers of rubber industry and other hazardous fields and in agriculture workers suffering from asthma or COPD. The study involved 33 workers of hazardous industries of Moscow and 35 agriculture workers. Methods used included questionnaire, physical examination, spirometry, bronchodilating test, methacholine challenge test, peak flowmetry, measurements of NO in the exhaled air (NOexh) and total IgE level before and after treatment with troventol under the continuing hazardous exposure condition. The daily dose of troventol depended on the severity of the disease and ranged 80 to 240 ΞΌg. The therapy with troventol has resulted in improvement of cough from 1.6 to 1.2 score (Ρ€ ≀ 0.05) and dyspnea from 1.12 to 0.8 (Ρ€ ≀ 0.04). Asthma attacks ceased in 39.7 % of the workers. Number of the workers having normal Tiffeneau index increased from 36.4 to 48.5 %. Bronchial hyperreactivity reduced. NOexh became normal in 24% of the patients. The drug was generally well tolerated.Π‘Ρ€Π΅Π΄ΠΈ ΠΏΡ€ΠΎΡ„Π΅ΡΡΠΈΠΎΠ½Π°Π»ΡŒΠ½Ρ‹Ρ… Π·Π°Π±ΠΎΠ»Π΅Π²Π°Π½ΠΈΠΉ патология Π»Π΅Π³ΠΊΠΈΡ… составляСт ΠΎΡ‚ 15 Π΄ΠΎ 35%, ΠΏΡ€ΠΈΡ‡Π΅ΠΌ Π½Π° долю хроничСской обструктивной Π±ΠΎΠ»Π΅Π·Π½ΠΈ Π»Π΅Π³ΠΊΠΈΡ… (Π₯ΠžΠ‘Π›) ΠΈ Π±Ρ€ΠΎΠ½Ρ…ΠΈΠ°Π»ΡŒΠ½ΠΎΠΉ астмы (БА) приходится ΠΏΠΎΠ»ΠΎΠ²ΠΈΠ½Π° случаСв. ЦСлью исслСдования явилась ΠΎΡ†Π΅Π½ΠΊΠ° клиничСской эффСктивности ΠΈ бСзопасности Ρ‚Ρ€ΠΎΠ²Π΅Π½Ρ‚ΠΎΠ»Π° Ρƒ Ρ€Π°Π±ΠΎΡ‚Π½ΠΈΠΊΠΎΠ² ΠΊΠ°ΡƒΡ‡ΡƒΠΊΠΎΠ²ΠΎΠ³ΠΎ ΠΈ Π΄Ρ€ΡƒΠ³ΠΈΡ… Π²Ρ€Π΅Π΄Π½Ρ‹Ρ… производств ΠΈ сСльского хозяйства, ΡΡ‚Ρ€Π°Π΄Π°ΡŽΡ‰ΠΈΡ… БА ΠΈ Π₯ΠžΠ‘Π›. Нами Π±Ρ‹Π»ΠΎ обслСдовано 33 Ρ€Π°Π±ΠΎΡ‡ΠΈΡ… Π²Ρ€Π΅Π΄Π½Ρ‹Ρ… производств ΠœΠΎΡΠΊΠ²Ρ‹ ΠΈ 35 Ρ€Π°Π±ΠΎΡ‚Π½ΠΈΠΊΠΎΠ² сСльского хозяйства. Использовали Π°Π½ΠΊΠ΅Ρ‚Π½Ρ‹ΠΉ скрининг, Π²Ρ€Π°Ρ‡Π΅Π±Π½Ρ‹ΠΉ осмотр, ΡΠΏΠΈΡ€ΠΎΠΌΠ΅Ρ‚Ρ€ΠΈΡŽ с Π±Ρ€ΠΎΠ½Ρ…ΠΎΠ΄ΠΈΠ»Π°Ρ‚Π°Ρ†ΠΈΠΎΠ½Π½Ρ‹ΠΌ тСстом, Π±Ρ€ΠΎΠ½Ρ…ΠΎΠΏΡ€ΠΎΠ²ΠΎΠΊΠ°Ρ†ΠΈΠΎΠ½Π½Ρ‹ΠΉ тСст с ΠΌΠ΅Ρ‚Π°Ρ…ΠΎΠ»ΠΈΠ½ΠΎΠΌ, ΠΏΠΈΠΊΡ„Π»ΠΎΡƒΠΌΠ΅Ρ‚Ρ€ΠΈΡŽ, опрСдСляли оксид Π°Π·ΠΎΡ‚Π° Π²Ρ‹Π΄Ρ‹Ρ…Π°Π΅ΠΌΠΎΠ³ΠΎ Π²ΠΎΠ·Π΄ΡƒΡ…Π° (NOexh) ΠΈ ΠΎΠ±Ρ‰ΠΈΠΉ IgE ΠΊΡ€ΠΎΠ²ΠΈ Π΄ΠΎ ΠΈ послС лСчСния Ρ‚Ρ€ΠΎΠ²Π΅Π½Ρ‚ΠΎΠ»ΠΎΠΌ Π² условиях продолТСния ΠΊΠΎΠ½Ρ‚Π°ΠΊΡ‚Π° с нСблагоприятными Ρ„Π°ΠΊΡ‚ΠΎΡ€Π°ΠΌΠΈ. Буточная Π΄ΠΎΠ·Π° Ρ‚Ρ€ΠΎΠ²Π΅Π½Ρ‚ΠΎΠ»Π° зависСла ΠΎΡ‚ тяТСсти заболСвания ΠΈ составила ΠΎΡ‚ 80 Π΄ΠΎ 240 ΠΌΠΊΠ³. На Ρ„ΠΎΠ½Π΅ Ρ‚Π΅Ρ€Π°ΠΏΠΈΠΈ Ρ‚Ρ€ΠΎΠ²Π΅Π½Ρ‚ΠΎΠ»ΠΎΠΌ ΠΈΠ½Ρ‚Π΅Π½ΡΠΈΠ²Π½ΠΎΡΡ‚ΡŒ кашля ΡƒΠΌΠ΅Π½ΡŒΡˆΠΈΠ»Π°ΡΡŒ Π² срСднСм с 1,6 Π΄ΠΎ 1,2 Π±Π°Π»Π»Π° (Ρ€ ≀ 0,05), ΠΎΠ΄Ρ‹ΡˆΠΊΠΈ β€” с 1,12 Π΄ΠΎ 0,8 Π±Π°Π»Π»Π° (Ρ€ ≀ 0,04), приступы ΡƒΠ΄ΡƒΡˆΡŒΡ ΠΏΡ€Π΅ΠΊΡ€Π°Ρ‚ΠΈΠ»ΠΈΡΡŒ Ρƒ 39,7 % Ρ€Π°Π±ΠΎΡ‡ΠΈΡ…. Число Ρ€Π°Π±ΠΎΡ‡ΠΈΡ… с Π½ΠΎΡ€ΠΌΠ°Π»ΡŒΠ½Ρ‹ΠΌ индСксом Π’ΠΈΡ„Ρ„Π½ΠΎ ΡƒΠ²Π΅Π»ΠΈΡ‡ΠΈΠ»ΠΎΡΡŒ с 36,4 Π΄ΠΎ 48,5 %, ΠΎΡ‚ΠΌΠ΅Ρ‡Π΅Π½ΠΎ ΡƒΠΌΠ΅Π½ΡŒΡˆΠ΅Π½ΠΈΠ΅ гипСррСактивности Π±Ρ€ΠΎΠ½Ρ…ΠΎΠ² Π² тСстС с ΠΌΠ΅Ρ‚Π°Ρ…ΠΎΠ»ΠΈΠ½ΠΎΠΌ. Π£ 24 % ΠΏΠ°Ρ†ΠΈΠ΅Π½Ρ‚ΠΎΠ² нормализовался NOexh. ΠŸΠ΅Ρ€Π΅Π½ΠΎΡΠΈΠΌΠΎΡΡ‚ΡŒ ΠΏΡ€Π΅ΠΏΠ°Ρ€Π°Ρ‚Π° Π² Ρ†Π΅Π»ΠΎΠΌ Π±Ρ‹Π»Π° Ρ…ΠΎΡ€ΠΎΡˆΠ΅ΠΉ
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