Exploring knowledge exchange: a useful framework for practice and policy

Knowledge translation is underpinned by a dynamic and social knowledge exchange process but there are few descriptions of how this unfolds in practice settings. This has hampered attempts to produce realistic and useful models to help policymakers and researchers understand how knowledge exchange works. This paper reports the results of research which investigated the nature of knowledge exchange. We aimed to understand whether dynamic and fluid definitions of knowledge exchange are valid and to produce a realistic, descriptive framework of knowledge exchange. Our research was informed by a realist approach. We embedded a knowledge broker within three service delivery teams across a large mental health organisation, each of whom was grappling with specific challenges. The knowledge broker participated in the team's problem-solving process and collected observational fieldnotes. We also interviewed the team members. Observational and interview data were analysed quantitatively and qualitatively in order to determine and describe the nature of the knowledge exchange process in more detail. This enabled us to refine our conceptual framework of knowledge exchange. We found that knowledge exchange can be understood as a dynamic and fluid process which incorporates distinct forms of knowledge from multiple sources. Quantitative analysis illustrated that five broadly-defined components of knowledge exchange (problem, context, knowledge, activities, use) can all be in play at any one time and do not occur in a set order. Qualitative analysis revealed a number of distinct themes which better described the nature of knowledge exchange. By shedding light on the nature of knowledge exchange, our findings problematise some of the linear, technicist approaches to knowledge translation. The revised model of knowledge exchange which we propose here could therefore help to reorient thinking about knowledge exchange and act as a starting point for further exploration and evaluation of the knowledge exchange process

Ixodes brunneus (Acari: Ixodidae) from Two Bird Hosts: A New Michigan Tick

The tick Ixodes brunneus Koch (Acari: Ixodidae) is reported for the first time in Michigan from two bird hosts at two locations in the lower peninsula. All stages of this tick exclusively feed on birds, and are primarily known from the southern U.S., although abundant records occur from northern states. The role of this species as a vector of pathogens is discussed

Cold gas in group-dominant elliptical galaxies

We present IRAM 30m telescope observations of the CO(1-0) and (2-1) lines in a sample of 11 group-dominant elliptical galaxies selected from the CLoGS nearby groups sample. Our observations confirm the presence of molecular gas in 4 of the 11 galaxies at >4 sigma significance, and combining these with data from the literature we find a detection rate of 43+-14%, comparable to the detection rate for nearby radio galaxies, suggesting that group-dominant ellipticals may be more likely to contain molecular gas than their non-central counterparts. Those group-dominant galaxies which are detected typically contain ~2x10^8 Msol of molecular gas, and although most have low star formation rates (<1 Msol/yr) they have short depletion times, indicating that the gas must be replenished on timescales ~100 Myr. Almost all of the galaxies contain active nuclei, and we note while the data suggest that CO may be more common in the most radio-loud galaxies, the mass of molecular gas required to power the active nuclei through accretion is small compared to the masses observed. We consider possible origin mechanisms for the gas, through cooling of stellar ejecta within the galaxies, group-scale cooling flows, and gas-rich mergers, and find probable examples of each type within our sample, confirming that a variety of processes act to drive the build up of molecular gas in group-dominant ellipticals.Comment: 9 pages, 5 postscript figures, 4 tables, accepted by A&A. Revised throughout in response to referee's comments, including updates to Table 1 and Figure 4, and addition of Figure

Associations Between Financial Strain and Emotional Well-Being With Physiological Responses to Acute Mental Stress

OBJECTIVE: To investigate associations between financial strain and emotional wellbeing, health, and physiological responses to acute mental stress. METHODS: Participants were 542 healthy men and women aged 53-76y from the Whitehall II study divided into those who reported no (n = 316), some (n =135) or moderate/severe (n = 91) financial strain. Emotional wellbeing and self-reported health were assessed at baseline and 3 years later. Laboratory mental stress testing involved assessment of blood pressure (BP), heart rate, and lipid reactivity and recovery, and plasma interleukin 6 (IL-6) responses to challenging behavioral tasks. Analyses adjusted for objective financial status, age, sex, socioeconomic status (SES) and marital status. RESULTS: Financial strain was positively associated with more depressive symptoms, lower positive affect, greater loneliness, and lower optimism, self-esteem and sense of control, and with poorer self-reported physical health, mental health and sleep (all p <.001). Longitudinally, financial strain predicted poorer outcomes 3 years later, but associations were attenuated after baseline levels were taken into account. Financial strain was associated with reduced systolic and diastolic BP reactivity to acute stress (mean systolic BP increase 32.34 ± 15.2, 28.95 ± 13.1 and 27.26 ± 15.2 mmHg in the none, some, and moderate/severe financial strain groups), but not with heart rate, IL-6 or lipid responses. CONCLUSIONS: Financial strain was correlated with a range of emotional and health-related outcomes independently of objective financial status. The diminished BP reactions to acute mental stress suggest that financial strain may contribute to dynamic chronic allostatic load

Seroprevalence of Hepatitis E among Boston Area Travelers, 2009-2010

We determined the prevalence of IgG antibodies to hepatitis E virus (anti-HEV IgG) among travelers attending Boston-area travel health clinics from 2009 to 2010. Pre-travel samples were available for 1,356 travelers, with paired pre- and post-travel samples for 450 (33%). Eighty of 1,356 (6%) pre-travel samples were positive for anti-HEV IgG. Compared with participants who had never lived in nor traveled to a highly endemic country, the pre-travel prevalence odds ratio (POR) of anti-HEV IgG among participants born in or with a history of previous travel to a highly endemic country was increased (POR = 4.8, 95% CI = 2.3–10.3 and POR = 2.6, 95% CI = 1.4–5.0, respectively). Among participants with previous travel to a highly endemic country, anti-HEV IgG was associated with age > 40 years (POR = 3.7, 95% CI = 1.3–10.2) and travel history to ≥ 3 highly endemic countries (POR = 2.7, 95% CI = 1.2–5.9). Two participants may have contracted HEV infection during their 2009–2010 trip

Series Expansions for the Massive Schwinger Model in Hamiltonian lattice theory

It is shown that detailed and accurate information about the mass spectrum of the massive Schwinger model can be obtained using the technique of strong-coupling series expansions. Extended strong-coupling series for the energy eigenvalues are calculated, and extrapolated to the continuum limit by means of integrated differential approximants, which are matched onto a weak-coupling expansion. The numerical estimates are compared with exact results, and with finite-lattice results calculated for an equivalent lattice spin model with long-range interactions. Both the heavy fermion and the light fermion limits of the model are explored in some detail.Comment: RevTeX, 10 figures, add one more referenc

Hamiltonian Study of Improved U(1U(1 Lattice Gauge Theory in Three Dimensions

A comprehensive analysis of the Symanzik improved anisotropic three-dimensional U(1) lattice gauge theory in the Hamiltonian limit is made. Monte Carlo techniques are used to obtain numerical results for the static potential, ratio of the renormalized and bare anisotropies, the string tension, lowest glueball masses and the mass ratio. Evidence that rotational symmetry is established more accurately for the Symanzik improved anisotropic action is presented. The discretization errors in the static potential and the renormalization of the bare anisotropy are found to be only a few percent compared to errors of about 20-25% for the unimproved gauge action. Evidence of scaling in the string tension, antisymmetric mass gap and the mass ratio is observed in the weak coupling region and the behaviour is tested against analytic and numerical results obtained in various other Hamiltonian studies of the theory. We find that more accurate determination of the scaling coefficients of the string tension and the antisymmetric mass gap has been achieved, and the agreement with various other Hamiltonian studies of the theory is excellent. The improved action is found to give faster convergence to the continuum limit. Very clear evidence is obtained that in the continuum limit the glueball ratio $M_{S}/M_{A}$ approaches exactly 2, as expected in a theory of free, massive bosons.Comment: 13 pages, 15 figures, submitted to Phys. Rev.

Path Integral Monte Carlo Approach to the U(1) Lattice Gauge Theory in (2+1) Dimensions

Path Integral Monte Carlo simulations have been performed for U(1) lattice gauge theory in (2+1) dimensions on anisotropic lattices. We extractthe static quark potential, the string tension and the low-lying "glueball" spectrum.The Euclidean string tension and mass gap decrease exponentially at weakcoupling in excellent agreement with the predictions of Polyakov and G{\" o}pfert and Mack, but their magnitudes are five times bigger than predicted. Extrapolations are made to the extreme anisotropic or Hamiltonian limit, and comparisons are made with previous estimates obtained in the Hamiltonian formulation.Comment: 12 pages, 16 figure

A New Finite-lattice study of the Massive Schwinger Model

A new finite lattice calculation of the low lying bound state energies in the massive Schwinger model is presented, using a Hamiltonian lattice formulation. The results are compared with recent analytic series calculations in the low mass limit, and with a new higher order non-relativistic series which we calculate for the high mass limit. The results are generally in good agreement with these series predictions, and also with recent calculations by light cone and related techniques

Density Matrix Renormalisation Group Approach to the Massive Schwinger Model

The massive Schwinger model is studied, using a density matrix renormalisation group approach to the staggered lattice Hamiltonian version of the model. Lattice sizes up to 256 sites are calculated, and the estimates in the continuum limit are almost two orders of magnitude more accurate than previous calculations. Coleman's picture of `half-asymptotic' particles at background field theta = pi is confirmed. The predicted phase transition at finite fermion mass (m/g) is accurately located, and demonstrated to belong in the 2D Ising universality class.Comment: 38 pages, 18 figures, submitted to PR