4,617 research outputs found

    Building the field of health policy and systems research: framing the questions.

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    In the first of a series of articles addressing the current challenges and opportunities for the development of Health Policy & Systems Research (HPSR), Kabir Sheikh and colleagues lay out the main questions vexing the field

    Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection

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    Coinfection with hepatitis B virus (HBV) is a common occurrence in human immunodeficiency virus (HIV)–positive patients and an increasing cause of morbidity and mortality. The CD8+ T cell response is critical for long-term control of HBV in patients resolving acute infection. Here, we examine the effect of HIV on HBV-specific CD8+ T cell responses in patients who have resolved HBV infection. A cross-sectional study showed a reduction in HBV-specific CD8+ T cell responses in HIV-positive, HBV-immune patients, compared with those in HIV-negative, HBV-immune patients. A longitudinal study of a subgroup of patients examined whether this attrition could be reversed by effective antiretroviral therapy. The introduction of highly active antiretroviral therapy (HAART) resulted in reconstitution of some HBV-specific CD4+ and CD8+ T cell responses, in association with restoration of CD4+ T cell counts. These data provide a mechanism to account for the observed impairment of control of HBV infection in the setting of HIV infection and support the ability of HAART to reconstitute functionally active T cell responses

    Quark mass density- and temperature- dependent model for strange quark matter

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    It is found that the radius of a stable strangelet decreases as the temperature increases in a quark mass density-dependent model. To overcome this difficulty, we extend this model to a quark mass density- and temperature- dependent model in which the vacuum energy density at zero baryon density limit B depends on temperature. An ansatz is introduced and the regions for the best choice of the parameters are studied.Comment: 5 pages, 4 figure

    Maximum Confidence Quantum Measurements

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    We consider the problem of discriminating between states of a specified set with maximum confidence. For a set of linearly independent states unambiguous discrimination is possible if we allow for the possibility of an inconclusive result. For linearly dependent sets an analogous measurement is one which allows us to be as confident as possible that when a given state is identified on the basis of the measurement result, it is indeed the correct state.Comment: 4 pages, 2 figure

    Fidelity and the communication of quantum information

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    We compare and contrast the error probability and fidelity as measures of the quality of the receiver's measurement strategy for a quantum communications system. The error probability is a measure of the ability to retrieve classical information and the fidelity measures the retrieval of quantum information. We present the optimal measurement strategies for maximizing the fidelity given a source that encodes information on the symmetric qubit-states

    A history of the Department of Library Science at the University of Northern Iowa, 1948-1968

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    The purpose of this research was to compile a descriptive chronological history of the Department of Library Science at UNI from 1948 through 1968. Faculty, curriculum, facilities, and influencing factors were particularly noted. Information was obtained through personal interviews with faculty members from the period, interview-questionnaires, and a search of university Bulletins, budgets, correspondence, and Faculty Senate minutes. The facts gathered were then presented chronologically within the areas of curriculum, faculty, facilities, and other information. A separate section contained the comparison of the Department of Library Science at UNI with the general pattern of development of education for school librarians. The faculty was found to be small in number throughout the period, and they had a positive influence on the department\u27s growth. The number of courses offered increased little, but the content did change. Facilities grew with the department. Departmental requirements surpassed state certification requirements. The department\u27s development did follow the pattern of development of school librarian education; it moved from a technical to a philosophical approach and then to the master\u27s degree program
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