57 research outputs found
Friend or foe? The current epidemiologic evidence on selenium and human cancer risk.
Scientific opinion on the relationship between selenium and the risk of cancer has undergone radical change over the years, with selenium first viewed as a possible carcinogen in the 1940s then as a possible cancer preventive agent in the 1960s-2000s. More recently, randomized controlled trials have found no effect on cancer risk but suggest possible low-dose dermatologic and endocrine toxicity, and animal studies indicate both carcinogenic and cancer-preventive effects. A growing body of evidence from human and laboratory studies indicates dramatically different biological effects of the various inorganic and organic chemical forms of selenium, which may explain apparent inconsistencies across studies. These chemical form-specific effects also have important implications for exposure and health risk assessment. Overall, available epidemiologic evidence suggests no cancer preventive effect of increased selenium intake in healthy individuals and possible increased risk of other diseases and disorders
Effect of dietary vitamin e and aging on tissue lipofuscin pigment concentration in mice.
Inhibition by ionol and ?-hydroxybutyric acid of lipid peroxidation when activated in emotional-pain stress
Lipid peroxidation in experimental myocardial infarction: Action of hyperbaric oxygenation
Chemical nature of fluorescent products accumulating in lipids from the lenses of mice with hereditary cataract
Effect of opioid neuropeptides on the prostaglandin system and on lipid peroxidation in the myocardium damaged by stress
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