Anemia in Antiretroviral Naïve HIV/AIDS Patients: A Study from Eastern India

Background: Hematological manifestations are common throughout the course of HIV infection. Impact of anemia is the most significant among them. The present study was undertaken to evaluate the etiologies underlying anemia in HIV/AIDS. Methods This was a non randomized cross sectional observational study conducted in a tertiary care hospital of India over a period of 2 years. One hundred and fifty HIV patients were screened. Thorough clinical and laboratory evaluation was done in 50 randomly selected anemic cases. Results: Proper etiological diagnosis could be reached in 46 patients. Among them correlation between Hb% and CD4 count was statistically insignificant (p = 0.074, r = 0.47) whereas it was significant with absolute lymphocyte and CD4 count (p = 0.006, r = 0.41). There was better correlation of bone marrow iron status with percent saturation of transferrin (p = 0.003, r = 0.54) than with serum ferritin (p = 0.055, r = 0.09). Bone marrow iron status did not have any relationship with CD4 count. Anemia of chronic disease was the commonest etiology (37%) followed by HIV related myelodysplastic syndrome (31%), iron deficiency anemia (13%), bone marrow suppression due to direct involvement by some infective process (7%). Aplastic anemia, multiple myeloma, Hodgkin’s disease, pure red cell aplasia, hemophagocytic lymphohistiocytosis and vitamin B12 deficiency were detected in one case (2%) each. Conclusions: Etiologies of anemia in HIV/AIDS are multifactorial with anemia of chronic disease being the commonest. For screening of iron deficiency in this group, percent saturation is a better tool than serum ferritin. Absolute lymphocyte count can sometimes be used as a surrogate marker of immunological status in antiretroviral naïve HIV patients, particularly in resource poor areas

Role Of Electron-Electron Scattering On Spin Transport In Single Layer Graphene

In this work, the effect of electron-electron scattering on spin transport in single layer graphene is studied using semi-classical Monte Carlo simulation. The D'yakonov-P'erel mechanism is considered for spin relaxation. It is found that electron-electron scattering causes spin relaxation length to decrease by 35% at 300 K. The reason for this decrease in spin relaxation length is that the ensemble spin is modified upon an e-e collision and also e-e scattering rate is greater than phonon scattering rate at room temperature, which causes change in spin relaxation profile due to electron-electron scattering. (C) 2014 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution 3.0 Unported License.Microelectronics Research Cente

Three flavour Quark matter in chiral colour dielectric model

We investigate the properties of quark matter at finite density and temperature using the nonlinear chiral extension of Colour Dielectric Model (CCM). Assuming that the square of the meson fields devlop non- zero vacuum expectation value, the thermodynamic potential for interacting three flavour matter has been calculated. It is found that $$and$$ remain zero in the medium whereas $$ changes in the medium. As a result, $u$ and $d$ quark masses decrease monotonically as the temperature and density of the quark matter is increased.In the present model, the deconfinement density and temperature is found to be lower compared to lattice results. We also study the behaviour of pressure and energy density above critical temperature.Comment: Latex file. 5 figures available on request. To appear in Phys. Rev.

Growth of preferential attachment random graphs via continuous-time branching processes

A version of ``preferential attachment'' random graphs, corresponding to linear ``weights'' with random ``edge additions,'' which generalizes some previously considered models, is studied. This graph model is embedded in a continuous-time branching scheme and, using the branching process apparatus, several results on the graph model asymptotics are obtained, some extending previous results, such as growth rates for a typical degree and the maximal degree, behavior of the vertex where the maximal degree is attained, and a law of large numbers for the empirical distribution of degrees which shows certain ``scale-free'' or ``power-law'' behaviors.Comment: 20 page

Yelling Fire and Hacking: Why the First Amendment Does Not Permit Distributing DVD Decryption Technology?

One of the consequences of the black-hole "no-hair" theorem in general relativity (GR) is that gravitational radiation (quasi-normal modes) from a perturbed Kerr black hole is uniquely determined by its mass and spin. Thus, the spectrum of quasi-normal mode frequencies have to be all consistent with the same value of the mass and spin. Similarly, the gravitational radiation from a coalescing binary black hole system is uniquely determined by a small number of parameters (masses and spins of the black holes and orbital parameters). Thus, consistency between different spherical harmonic modes of the radiation is a powerful test that the observed system is a binary black hole predicted by GR. We formulate such a test, develop a Bayesian implementation, demonstrate its performance on simulated data and investigate the possibility of performing such a test using previous and upcoming gravitational wave observations

Probing electronic excitations in molecular conduction

We identify experimental signatures in the current-voltage (I-V) characteristics of weakly contacted molecules directly arising from excitations in their many electron spectrum. The current is calculated using a multielectron master equation in the Fock space of an exact diagonalized model many-body Hamiltonian for a prototypical molecule. Using this approach, we explain several nontrivial features in frequently observed I-Vs in terms of a rich spectrum of excitations that may be hard to describe adequately with standard one-electron self-consistent field (SCF) theories.Comment: Significantly different content -- inadequacy of SCF approach described with simple model, and a whole new class of experiments showing gate modulated current steps discussed in terms of excitations in the molecular many-body spac

Comment on ''Understanding the Area Proposal for Extremal Black Hole Entropy''

A. Ghosh and P. Mitra made the proposal how to explain the area law for the entropy of extreme black holes in some model calculations. I argue that their approach implicitly operates with strongly singular geometries and says nothing about the contribution of regular metrics of extreme black holes into the partition function.Comment: 5 pages, ReVTeX, no figures. Expanded from the journal version to include response to Ghosh and Mitra Reply