4,689 research outputs found
GALEX measurements of the Big Blue Bump as a tool to study bolometric corrections in AGNs
Active Galactic Nuclei emit over the entire electromagnetic spectrum with the
peak of the accretion disk emission in the far-UV, a wavelength range
historically difficult to investigate. We use here the GALEX (Galaxy Evolution
Explorer) Near-UV and Far-UV measurements (complemented with optical data from
Sloan Digital Sky Survey (SDSS) and XMM-Newton X-ray spectra) of a sample of 83
X-ray selected type 1 AGN extracted from the XMM-Newton Bright Serendipitous
Survey to study their spectral energy distribution (SED) in the optical, Near
and Far-UV and X-ray energy bands. We have constrained the luminosity of the
accretion disk emission component and calculated the hard X-ray bolometric
corrections for a significant sample of AGN spanning a large range in
properties (z, L(x)).Comment: 2 pages, 2 figures, To appear in refereed Proceedings of "X-ray
Astronomy 2009: Present Status, Multi-Wavelength Approach and Future
Perspectives", Bologna, Italy, September 7-11, 2009, AIP, eds. A. Comastri,
M. Cappi, and L. Angelin
Black-hole masses of type 1 AGN in the XMM-Newton bright serendipitous survey
We derive masses of the central super-massive black hole (SMBH) and accretion
rates for 154 type1 AGN belonging to a well-defined X-ray-selected sample, the
XMM-Newton Serendipitous Sample (XBS). To this end, we use the most recent
"single-epoch" relations, based on Hbeta and MgII2798A emission lines, to
derive the SMBH masses. We then use the bolometric luminosities, computed on
the basis of an SED-fitting procedure, to calculate the accretion rates, both
absolute and normalized to the Eddington luminosity (Eddington ratio). The
selected AGNs cover a range of masses from 10^7 to 10^10 Msun with a peak
around 8x10^8 Msun and a range of accretion rates from 0.01 to ~50 Msun/year
(assuming an efficiency of 0.1), with a peak at ~1 Msun/year. The values of
Eddington ratio range from 0.001 to ~0.5 and peak at 0.1.Comment: 14 pages, 11 figures. Accepted for publication in Astronomy &
Astrophysic
Botulinum toxin therapy: functional silencing of salivary disorders.
Botulinum toxin (BTX) is a neurotoxic protein produced by Clostridium botulinum, an anaerobic bacterium. BTX therapy is a safe and
effective treatment when used for functional silencing of the salivary glands in disorders such as sialoceles and salivary fistulas that may
have a post-traumatic or post-operative origin. BTX injections can be considered in sialoceles and salivary fistulas after the failure of or
together with conservative treatments (e.g. antibiotics, pressure dressings, or serial aspirations). BTX treatment has a promising role in
chronic sialadenitis. BTX therapy is highly successful in the treatment of gustatory sweating (Frey\u2019s syndrome), and could be considered
the gold standard treatment for this neurological disorder
Determinants associated with obesity and physical activity in the public and private schools of the city of palermo
Introduction: Obesity is a medical condition associated with premature death and it is a risk factor for many chronic diseases. In this context, performing a regular physical activity promotes a healthy lifestyle, with significant health benefits. The aim of the study was to investigate behaviors that increase the risk of obesity and the determinants that encourage physical activity among adolescents. Materials and methods: The HBSC (Health Behavior in School-aged Children) questionnaire was administered to students in Palermo's private and public schools. For the sampling of public schools the protocol of the HBSC Surveillance System was followed; for the private ones it was opportunistic. Results: Private school students are more likely to exercise more than 3 days per week (OR 1.58) and are more likely to exercise more than 2 times a week (OR 2.08). Obese students in private schools in Palermo are more likely to perform physical activity for less than 3 days a week (OR 3.52) and a higher risk of not having breakfast (OR 10.11) and a snack between main meals (OR 3.82) every day. For all the schools examined, it emerged that obese subjects are more likely not to consume fruit (OR 3.13), to stay more than 6 hours a day in front of PCs and video games (OR 3.24) and more than 2 hours a day in front of TV (OR 3.79). Male students are more likely to perform physical activity for more than 3 days per week (OR 1.48) and intense physical activity at least 2 times per week (OR 1.76) Conclusions: It is necessary to intervene early with training on school and family in order to promote correct and responsible food choices and increase the level of physical activity among students. Therefore prevention interventions must be an integral part of coherent strategies based on tests of agreed effectiveness in order to minimize the risk linked to the development of diseases
A critical analysis of the hydrino model
Recently, spectroscopic and calorimetric observations of hydrogen plasmas and
chemical reactions with them have been interpreted as evidence for the
existence of electronic states of the hydrogen atom with a binding energy of
more than 13.6 eV. The theoretical basis for such states, that have been dubbed
hydrinos, is investigated. We discuss both, the novel deterministic model of
the hydrogen atom, in which the existence of hydrinos was predicted, and
standard quantum mechanics. Severe inconsistencies in the deterministic model
are pointed out and the incompatibility of hydrino states with quantum
mechanics is reviewed.Comment: 9 page
Low value of detection of KRAS2 mutations in circulating DNA to differentiate chronic pancreatitis to pancreatic cancer
We read with great interest the article by Maire et al (2002), who evaluate the K-Ras mutations in circulating DNA to differentiate pancreatic cancer from chronic pancreatitis. Based on this, we also analysed KRAS2 mutations in the serum of 30 patients with pancreatic cancer and 40 patients with chronic pancreatitis. Pancreatic cancer patients were staged by means of dynamic computed tomography, magnetic resonance imaging, and angiography and/or endoscopic ultrasonography. Diagnosis was histologically confirmed for the patients who underwent surgery. The diagnosis of chronic pancreatitis was based on the radiologic data obtained by means of either endoscopic retrograde cholangiopancreatography or computed tomography. DNA was extracted from 20 ml of the serum by using the QIAmp Blood Kit (Qiagen) and the mutations in codon 12 of the K-ras gene were searched as described previously (Jiang et al, 1989). As positive controls, we used DNA from neoplastic tissues of 10 patients with pancreatic carcinoma by using the DNeasy Tissue Kit (Qiagen). For molecular analysis, DNA was amplified in the codon 12 region introducing a restriction site (GACCT) for digestion with BstNl restriction enzyme (PCR-RFLP). DNA from peripheral blood resulted not mutated in the 40 patients with chronic pancreatitis and in the 30 with pancreatic carcinoma, while DNA from pancreatic neoplastic tissue resulted mutated in 70% of the samples. To verify our results, all the samples were analysed by direct sequencing using Big Dye terminator v 1.1 cycle sequencing Kit and performing runs on ABI Prism 310 genetic analyzer (Applied Biosystem) Despite what was mentioned in Maire's article, we failed to find any mutations in all patients analysed, as well as we failed to correlate K-ras mutations with the levels of tumour markers such as Ca 19.9, CA242, CA50, CEA. The results of the present investigation lead us to these conclusions: (1) the eventual presence of cancer cells in peripheral blood may be a rare event, even if numerous reports support the detection of K-ras abnormalities in the serum, (2) neoplastic cells are supposed to circulate in clusters, and consequently their cognition could be hampered by a single blood sample extraction. (3) Large amounts of nonmutated DNA, coming from leucocytes held in the buffy coat layer, might also mask some vestiges of the mutant type of K-ras gene
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