Pattern recognition of acoustic emission signal during the mode I fracture mechanisms in carbon- epoxy composite

The aim of the paper is to use Acoustic Emission technique to distinguish the micro/macro failure mechanisms of carbon-epoxy composite laminates during Double Cantilever Beam (DCB) tests. In order to recognize and detect different damage mechanisms, Self-Organizing Map (SOM) method has been used to cluster the AE signals according with the fracture mode that originated them. In addition, most significate Learning vector quantization (LVQ) program has been applied to verify the signals. Five AE features were selected as main parameters: Rise-time, Counts, Energy, Duration and Amplitude. The results highlighted that different signals can be recognized and classified related to their origin. The failure mechanisms detected are Matrix cracking, delamination, and fiber breakage. Scanning Electron Microscopy (SEM) images validate the results. Mathematics data and experimental results confirmed a good converging of AE dat

Cohesive zone modelling of delamination response of a composite laminate with interleaved nylon 6,6 nanofibres

This work simulates numerically Double Cantilever Beam and End Notched Flexure experiments on Carbon Fibre Epoxy Resin specimens that have been performed by some of the authors in a previous work. Specimens have been nanomodified by interleaving plies with a layer of electrospun nanofibres in the delaminated interface. Eight different configurations of nanofibres have been used as interleave, for a total of 9 configurations (8 nanomodified plus the virgin one) to be simulated for both kind of tests to identify the cohesive zone parameters corresponding to the effect of nanofibre diameter, nanolayer thickness and nanofibre orientation on the delamination behaviour of the composite. Results showed that a bilinear damage law is necessary for almost all nanomodified configurations, and presented a clear relationship between nanomat layer parameters and the cohesive energy of the interface

Electrospun nanofibers as reinforcement for composite laminates materials – a review

In the last few decades nanofibers have been developed and introduced in a vast number of industrial and research applications. One of their most effective use is as interleaved reinforcement for composite laminate materials against delamination. Nanofibrous mats have the ideal morphology to be embedded between two plies of a laminate, and a vast and deep research has been carried out investigating their effect on the global behaviour of a composite laminate. This review is the first of its kind to date which presents a detailed state-of-the-art on the effect of nanofibrous interleaves into composite laminates with focus on the mechanical performances and behaviours of nanomodified materials. A detailed description of the working mechanisms of the nanointerleave under different load cases is presented, and a comparative analysis between papers in literature will provide readers with a powerful tool to understand and use nanofibers for reinforcing purposes

Supervised and non-supervised AE data classification of nanomodified CFRP during DCB tests

Aim of the paper is to use acoustic emissions to study the effect of electrospun nylon 6,6 Nanofibrous mat on carbon-epoxy composites during Double Cantilever beam (DCB) tests. In order to recognize the effect of the nanofibres and to detect different damage mechanisms, k-means clustering of acoustic emission signals applied to rise time, count, energy, duration and amplitude of the events is used. Supervised neural network (NN) is then applied to verify clustered signals. Results showed that clustered acoustic emission signals are a reliable tool to detect different damage mechanisms; neural network showed the method has a 99% of accuracy

Fracture mechanics of laser sintered cracked polyamide for a new method to induce cracks by additive manufacturing

This paper presents an experimental investigation on specimens manufactured by Selective Laser Sintering (SLS), with the purposes of giving designers advice when designing 3D printed parts, and laying the basis for a step forward in the field of fracture mechanics of 3D complex parts. The aim is to investigate the effect of building direction in Polyamide (PA) 3D printed samples and to assess whether a crack can be initiated directly from the sintering process for fracture mechanics study purposes. Six different configurations of Mode I Compact Tension (CT) specimens were manufactured and tested; the experiments were monitored by Digital Image Correlation (DIC) and fractured surfaces were analyzed using microscopy. Results showed that samples with better mechanical performance are those in which all the layers contain a portion of the crack. On the other hand, those with layers parallel to the crack plan offer a preferential pathway for the crack to propagate. DIC and fractography investigations showed that, under certain conditions, small-radius geometries, or too-close surfaces may glue depending on printer resolution. Experiments also showed that SLS is capable of printing specimens with internal cracks that can be used to study fracture mechanics of complex parts or parts with internal cracks

Double photoionization of propylene oxide: a coincidence study of the ejection of a pair of valence-shell electrons

Propylene oxide, a favorite target of experimental and theoretical studies of circular dichroism, was recently discovered in interstellar space, further amplifying the attention to its role in the current debate on protobiological homochirality. In the present work, a photoelectron-photoion-photoion coincidence technique, using an ion-imaging detector and tunable synchrotron radiation in the 18.0-37.0 eV energy range, permits us (i) to observe six double ionization fragmentation channels, their relative yields being accounted for about two-thirds by the couple (C2H4+, CH2O+) and one-fifth by (C2H3+, CH3O+); (ii) to measure thresholds for their openings as a function of photon energy; and (iii) to unravel a pronounced bimodality for a kinetic-energy-released distribution, fingerprint of competitive non-adiabatic mechanisms

Focus on the use of resveratrol in bladder cancer

Bladder cancer is the most common tumor of the urinary system, with a high incidence in the male population. Surgery and intravesical instillations can eradicate it, although recurrences are very common, with possible progression. For this reason, adjuvant therapy should be considered in all patients. Resveratrol displays a biphasic dose response both in vitro and in vivo (intravesical application) with an antiproliferative effect at high concentrations and antiangiogenic action in vivo (intraperitoneal application) at a low concentration, suggesting a potential role for it in clinical management as an adjuvant to conventional therapy. In this review, we examine the standard therapeutical approach to bladder cancer and the preclinical studies that have investigated resveratrol in xenotransplantation models of bladder cancer. Molecular signals are also discussed, with a particular focus on the STAT3 pathway and angiogenic growth factor modulation

The Mycobacterium tuberculosis protein tyrosine phosphatase MptpA features a pH dependent activity overlapping the bacterium sensitivity to acidic conditions

The Mycobacterium tuberculosis low-molecular weight protein tyrosine phosphatase (MptpA) is responsible for the inhibition of phagosome-lysosome fusion and is essential for the bacterium patho-genicity. This inhibition implies that M. tuberculosis is not exposed to a strongly acidic environment in vivo, enabling successful propagation in host cells. Remarkably, MptpA has been previously structurally and functionally investigated, with special emphasis devoted to the enzyme properties at pH 8.0. Considering that the virulence of M. tuberculosis is strictly dependent on the avoidance of acidic con-ditions in vivo, we analysed the pH-dependence of the structural and catalytic properties of MptpA. Here we show that this enzyme undergoes pronounced conformational rearrangements when exposed to acidic pH conditions, inducing a severe decrease of the enzymatic catalytic efficiency at the expense of phosphotyrosine (pTyr). In particular, a mild decrease of pH from 6.5 to 6.0 triggers a significant increase of K0.5 of MptpA for phosphotyrosine, the phosphate group of which we determined to feature a pKa2 equal to 5.7. Surface plasmon resonance experiments confirmed that MptpA binds poorly to pTyr at pH values < 6.5. Notably, the effectiveness of the MptpA competitive inhibitor L335-M34 at pH 6 does largely outperform the inhibition exerted at neutral or alkaline pH values. Overall, our observations indicate a pronounced sensitivity of MptpA to acidic pH conditions, and suggest the search for competitive in-hibitors bearing a negatively charged group featuring pKa values lower than that of the substrate phosphate group. (c) 2023 Elsevier B.V. and Societe Francaise de Biochimie et Biologie Moleculaire (SFBBM). All rights reserved

Sailor Perspectives and Recommendations for Communication About Divisive Events and Inclusion within the Fleet

Recent events, such as the death of George Floyd and the resulting Black Lives Matter (BLM) protests, the post elections attack on the U.S. Capitol, and the COVID-19 pandemic, have brought to light the challenges leaders in both private and public/governmental organizations face when communicating with employees about sensitive events. At both the national and global levels these issues are often tied to deep and long-held societal divisions. The U.S. Navy has frequently taken a progressive stance in supporting diversity and inclusion, and the Navy's recent steps to encourage inclusion and engage in necessary conversations are consistent with these actions. However, recent events and efforts to converse about these events have highlighted the challenges inherent in such communication. This study builds upon previous research focused on the tensions between participation and organizational control in online workplace communities (Aten & Salem, 2020). This research explored Sailors' experiences of sensitive conversations on various topics and of necessary conversations directed by Navy leadership following the attacks on the U.S. Capitol. This current research describes Sailors' perceptions of drivers and outcomes of sensitive conversations. It identifies four needed individual and organizational capacities to support successful conversations about sensitive subjects: metacognition, emotional regulation, cultural curiosity, and communication competence. Participants’ responses and related literature highlight two key conclusions. First, Sailors disagree on how the Navy should manage sensitive conversations: majority and minority groups’ perceptions differ on what topics require conversation, and fail to recognize that the inability to engage effectively in sensitive conversations is a military vulnerability. Second, Navy communication often demonstrates an inadequate capacity for managing these conversations: leaders lack self-awareness, emotional regulation is challenging, cultural curiosity is not developed, and the tensions generated by communication hierarchies limit communication effectiveness. These capability gaps constrain Sailors' positive perceptions of sensitive conversations which contribute to continued divisive conversations, reduced perceptions of inclusion, and increased risk from information warfare