Penicilliform anthropomorphic manipulator

In the article a description of robot-equippe

Sorption Properties of Polymeric Enterosorbent and Its Specific Modified Analogue in Simulated Cholera Toxin Solutions <I>in vitro</I>

Carried out was comparative study of the sorption properties in polymeric enterosorbent - chitosan, and its specific modified analogue obtained through absorption of anti-toxin immunoglobulins onto the soluble chitosan template. It is determined that soluble chitosan and its specific counterpart express high sorption activity in relation to cholera toxin, thus making lower its initial concentrations. Equilibrium adsorption capacity of the chitosan and its modified variant increase with the raise of initial cholera toxin concentration in the solution. Cholera toxin extraction rate was identified under static conditions. Adsorbate substance recovery rate was registered in the progression. In the course of experiments proved was modified sorbent specific sorption efficiency, occasioned by the presence of the active component in the analogue composition - namely, anti-toxic anticholeraic immunoglobulins. The data obtained are of the importance for further development of specific anticholeraic enterosorbent

Quantum analogue of the spin-flop transition for a spin pair

Quantum (step-like) magnetization curves are studies for a spin pair with antiferromagnetic coupling in the presence of a magnetic field parallel to the easy axis of the magnetic anisotropy. The consideration is done both analytically and numerically for a wide range of the anisotropy constants and spins up to $S \gtrsim 100$. Depending on the origin of the anisotropy (exchange or single-ion), the magnetization curve can demonstrate the jumps more than unity and the concentration of the unit jumps in a narrow range of the field. We also point the region of the problem parameters, where the behavior is quasiclassical for $S = 5$, and where system is substantially quantum in the limit $S \to \infty$.Comment: 5 pages, 5 figure

NEW WAY OF ISOLATION OF ENZYME COMPLEX OF CHOLERA VIBRIO - PROTEOVIBRIN BY MEANS OF ULTRAFILTRATION

The technology of isolation of the cholera vibrio complex of low-molecular enzymes related to pathogenicity factors, from cholera vaccine production wastes by means of concentrating ultrafiltration was developed. This technology allows to obtain standard series of the preparation termed proteovibrin which is free from the basic Vibrio cholerae immunogen - O-antigen, and possesses high activity of protease and. phospholipases A2 and. C. It is shown that proteovibrin is highly soluble in water and 0.14 molar NaCl solution, causes the production of antibodies in rabbits and is toxic for white mice. Its further examination seems to be promising, as well as its possible use as additional source of the cholera vibrio enzymes and. as tripsin-like preparation, applicable for protein raw material hydrolysis in production of microbiological nutrient media

Return Migration From Russia to Kyrgyzstan: Dynamics, Causes, and Structure

Received 9 April 2023. Accepted 25 July 2023. Published online 6 October 2023.The study’s significance lies in the need for comprehensive information on return labor migration from Russia to Kyrgyzstan and the profiles of return migrants, which would allow us to anticipate spatial mobility in the future. This is particularly relevant due to Russia’s interest in new migrants as essential labor force to address the demographic crisis. The Kyrgyzstani government also requires these data to prevent unemployment among return migrants. This paper aims to assess return migration dynamics and its structure, uncover the causes, goals, and reasons for recurrent migration to Russia, and examine the expectations of Russia’s social and migration policy during the special military operation. The empirical analytical base comprises the results of a questionnaire survey of 515 return migrants and focused in-depth interviews with 37 return migrants in Kyrgyzstan in October–November 2022, as well as a questionnaire survey of 425 labor migrants and focused interviews with 52 labor migrants in November–December 2022 in Moscow. The findings indicate that return migration is voluntary and spontaneous. The official estimate of the scope of return migration, as well as the prospects of labor migration to Russia after February 24th, 2022 and the imposition of anti-Russian sanctions, remains unclear. The structure of return migration aligns with the structure of labor migration in Russia in terms of gender, age, and employment sectors. The motivation behind the decision to return has a cumulative effect. However, most respondents cited personal and family issues as the main reasons for return migration. Approximately 30% of respondents, regardless of gender, attributed the special military operation and the worsening economic situation in Russia as reasons for returning to their home country. About 22% of respondents envision recurrent migration to Russia in the near future, while around 30% have not yet decided. Labor migrants seek institutional support from Russia, including assistance in preparing registration documents, social insurance provision, removal of administrative obstacles for employment, and the creation of favorable conditions for adaptation

Prospective Sorption Matrices for Antitoxic Cholera Enterosorbent Constructing

Demonstrated is the possibility of constructing of oral anti-cholera preparations based on sorption matrices with immobilized specific ligand. Various enterosorbents (activated charcoal, polysorb, polyfepan, and chitosan) have been used as sorption matrices, cholera antitoxic immunoglobulins (ATIg) – as specific ligands. Toxin-neutralizing activity of the ATIg immobilized on polysorb has been observed in vivo in 1:64000 dilutions and that of ATIg immobilized on activated charcoal, polyfepan, and chitosan – in 1:32000. Their specific activity in vitro has been defined in dot-blot immunoassay in 1:10000 and 1:5000 dilutions, respectively. High toxin-neutralizing activity, as well as specific one has proved the suitability of all tested matrices for antitoxic cholera enterosorbents constructing. However, polysorb and chitosan are accepted to be the most prospective matrices in view of the studied characteristics and properties. To stabilize the properties of the obtained experimental prototype sorbents, AT/Ig-polysorb and AT/Ig-chitosan, applied has been the method of liophilisation with glycocol stabilizer. Dried samples retain their original biological properties

Properties of Neutral Charmed Mesons in Proton--Nucleus Interactions at 70 GeV

The results of treatment of data obtained in the SERP-E-184experiment "Investigation of mechanisms of the production of charmed particles in proton-nucleus interactions at 70 GeV and their decays" by irradiating the active target of the SVD-2 facility consisting of carbon, silicon, and lead plates, are presented. After separating a signal from the two-particle decay of neutral charmed mesons and estimating the cross section for charm production at a threshold energy {\sigma}(c\v{c})=7.1 \pm 2.4(stat.) \pm 1.4(syst.) \mub/nucleon, some properties of D mesons are investigated. These include the dependence of the cross section on the target mass number (its A dependence); the behavior of the differential cross sections d{\sigma}/dpt2 and d{\sigma}/dxF; and the dependence of the parameter {\alpha} on the kinematical variables xF, pt2, and plab. The experimental results in question are compared with predictions obtained on the basis of the FRITIOF7.02 code.Comment: 9 pages, 9 figures,3 table